Kava kava and wormwood interactions

[George1012]

Looking for info about interactions between these two herbs as I've heard both kava and wormwood are tricky and you need to be careful. I'm not interested in anything about absinthe. I have used wormwood and other herbs like passionflower and damiana to intensify effects of cannabis. From personal experience both passionflower and wormwood intensify effects of cannabis tremendously, like the mango before blazing trick times ten. I'm wondering if I can combine both kava and wormwood without there being any interactions. Again I ask because I've heard that combining kava with the wrong herbs or medicines can wreak havoc on your liver.

 

[d1nach]

Whats the reasoning behind the wormwood i thought it was toxic?

 

[Limpet_Chicken]

It is, and it tastes foul also (bitter as wormwood is an old aphorism in fact). Primary bioactives are thujones. These are GABA antagonists. Thujone is also hepatotoxic. CERTAIN preparations of kava are also so, those including the stem peelings or stems in extracts, rather than the root, these should be avoided utterly. The root preparations appear to lack the toxic kavalactones present in the above-ground portions of the plant

These two would just counteract each other. No point.

 

[d1nach]

I read identical things about wormwood.

Id skip the wormwood all together atless you have more info because kava does have what seems to be evidence it does something perhaps making the risk worth it.

 

[Limpet_Chicken]

I see SO little point of combining an antagonist/inverse agonist (cant remember which thujone is) with an agonist (PAM) at the same receptor. Its pulling in the same direction as you push, reductio ad absurdum.

And wormwood REALLY tastes like a million tons of arsehole covered in shit. Its one of the vilest things I've ever tasted (used to have plants), worse even than ayahuasca brews featuring P.harmala, or poppy pod tea. Sure, I've smelled/tasted worse (like the experience with a biogenically generated thiol of some sort or som ething like one, that was potent enough to make people cross the road, from quite some distance and which came out even INSIDE ,
nasal fluid.) still, Artemesia spp. are up there. Not the kind of gross that'll befoul a room or evacuate a neighborhood or city, but still, its up there in terms of nasty when it comes to taste.