• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

JWH solubility in edible vehicles

T

TCStyle

Bluelighter
Joined
Aug 15, 2005
Messages
43
I want to make some JWH-015 cookies. At first I figured it would be just like THC cookies, but then I read that JWH solubility in fatty carriers is NOT similar to THC.

Basically I want to know what substance I could dissolve JWH-015 in (possibly a mg/ml ratio if available) and what temperature would decompose that mixture.
 
JWH-015?

You have the wrong drug or the wrong number. JWH-015 is a selective CB2 agonist, CB1 is the receptor you want to agonize to get high.

JWH-018 is much less selective (with CB1 and CB2 binding afinity fairly similar), and is the most common JWH drug.


JWH-018 is dissolves wonderfully in acetone, which you don't want in your cookies.

It dissolves poorly in ethanol, but that might be your best bet. Dissolve in ethanol, then dump that into the batter and mix it up real quick (so as the JWH-018 precipitates out, it's well distributed). Generally people have had very varied experiences with eating JWH's however - stories of "I took X mg of it and it did nothing, so i took twice as much, and i had a horrible overdose panic attack" are almost ubiquitous, and doses are much higher than vaporized.

I would council against JWH-xxx cookies.
 
to be more accurate than food. make a tincture with a known mg/ml then you will have a better idea of exactly how much you are taking
 
^Yes, in principle this is correct. But as a general note, the oral bioavailability of JWH-015/018 is very low and depends furthermore much on stomach content etc.

I would not try to take those cannabinoids orally. A dose that makes you feel merely stoned one day can shoot you into the orbit the other day. As said before: Bad reproducibility.

- Murphy
 
i was also very disappointed with the effects of oral JWH-073, i go to great lengths to avoid smoking anything for health reasons and i had high hopes for oral JWH but IME the oral experience highlights a lot of negative elements eg all psychedelic ideation was missing and replaced with a gauzy inarticulate styrofoam kind of stondedness, it became highly sedative and more of a zombie-high as opposed to the sharp, stimulating, psychedelic effects that make JWH-073 worth the (occasional) risk.
 
if you just had to make food with it, i would suggest mixing it in with the eggs first. even if its not very soluble, eggs make emulsions very well. just dont beat them so much that you get meringue! or maybe you should...actually i think that meringue would be an optimal way to deliver less soluble compounds.
 
JWH meringue? Nice. I know ethanol isn't the best thing to dissolve JWH's in, but does anyone have the solubility info for various JWH's in ethanol? I've heard 073 can go up to 30mg/mL. I've got 95% ethanol btw. Seems like somewhere I'd read that 018 could be dissolved at 20ish mg/mL, but I kinda doubt that as most people have had a lot of difficulty. Haven't seen a whole lot about solubility of 133, 200, or 250. I'm particularly interested in the latter, as it lacks the napthalene ring which could possibly be carcinogenic if freed during pyrolysis.
 
Last edited:
JWH may not be directly fat soluable, but the presense of fats will greatly assist the body in absoportion of said chemical, try a glass of full fat milk with it for example.

as stated more than once above, JWH is sometimes unpredictable in its strengh, so only a season/daily cannabinoid abuser should risk eating it.

I dont think ive ever eaten a (homemade) hash cookie which ive accidently made weak :) - my reciepe - no pain no gain

Smoking, or more accurately vape off foil (with a good torch lighter), is the best bang for your buck.
 
Last edited:
Works well in cake.
IME, if you use a high volume carrier (eg. you have to eat a relatively large portion for a single dose), and that carrier is fatty, then you minimize the variability. If the carrier is high volume, you reduce the margin of error present by differing consumption of foodstuffs prior to consuming your dose (ie. you ate some Burger King before the dose, vs. you drank a glass of 7-Up).

Overdoses happen when you calibrate your dose on non-fatty foodstuffs, then have the same dose with a fatty foodstuff. The fattiness causes greater uptake, and bang, you are stuck in horrible panic land for ages. Not fun.
 
i have done some experiemting with various jwh's and have found 073 to be good in an everclear shot. to increase solvency i just place the shot in a warm bath.

got bad side effects from 081 & alcohol taken orally on a couple of occassions.

have found that some fats do seem to greatly increase the strength & onset time of a few jwh's.

have not liked taking the jwh's just straight orally as kick in time and strength seems really unpredictable, but in an everclear shot kick in time, and strength seem to be pretty constant. 1 hour.

lately i have been experimenting with 200, and have found that dropping a few drops of grapeseed oil into the gel cap, shaking up a bit and swallowing seems to greatly increase kick in speed, (started feeling it creep up at 15min), and seems to make it kick in much stronger, i took 14mg, and got alot more than i did trying to smoke 12mg.
 
a friend of mine once made butterscotch out of a bunch of pot-butter. it actually worked pretty well.
 
MattPsy said:
Works well in cake.
IME, if you use a high volume carrier (eg. you have to eat a relatively large portion for a single dose), and that carrier is fatty, then you minimize the variability. If the carrier is high volume, you reduce the margin of error present by differing consumption of foodstuffs prior to consuming your dose (ie. you ate some Burger King before the dose, vs. you drank a glass of 7-Up).

Overdoses happen when you calibrate your dose on non-fatty foodstuffs, then have the same dose with a fatty foodstuff. The fattiness causes greater uptake, and bang, you are stuck in horrible panic land for ages. Not fun.
Click to expand...

That is some valuable info. Thanks a lot! - Murphy
 
You must log in or register to reply here.
Top