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jwh danger?

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cmiddy

cmiddy

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Jan 10, 2011
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I've recently been researching the jwh chemical and its permanent effects on the body and brain. I have expirmented with many kinds on jwh such as -018, -122, and -250 but decided to research it when i started hearing rumors (not sure if true or not) about it putting holes in your brain as well as having effects on future children. I can't seem to find any information to tell me what the danger factor (other than obvious side-effects) of jwh is. If you know anything about it, please enlighten me, thanks.
 
cmiddy said:
I've recently been researching the jwh chemical and its permanent effects on the body and brain. I have expirmented with many kinds on jwh such as -018, -122, and -250 but decided to research it when i started hearing rumors (not sure if true or not) about it putting holes in your brain as well as having effects on future children. I can't seem to find any information to tell me what the danger factor (other than obvious side-effects) of jwh is. If you know anything about it, please enlighten me, thanks.
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I can tell you straight away that it most likely doesn't cause 'holes in the brain'. Who the hell told you that? That sounds like some BS drug propaganda horror story someone has fed you.

I think that at the moment we don't really know what long term effects the drug will have. They might be a ticking time bomb, yet they might not. I would say that with infrequent, moderate use you're unlikely to suffer extreme long term issues, especially it causing an inability to have children. If I were you I would check out the jwh ruined my life thread for more info.

I personally would avoid these RCs, if they can still be called that with their popularity.
 
The "holes in brain" is a rumor. The scare-tactic people throw that one out there for every damned drug.

They're pretty likely to be carcinogenic - any of the ones with the napthyl moiety (with the possible exception of 081, which has an ether linkage on the napthyl - that often makes compounds with the napthyl moiety on them non-carcinogenic). The carcinogenicity would be via the same mechanism that napthalene is carcinogenic - the body doesn't know what to do with this big napthyl group, and resorts to oxidizing it to the carcinogenic epoxide. However, you can calculate out how much of the active component you're getting into your body (not that much) and how much napthalene that would be equivilent to (assuming it's equally carcinogenic as napthalene itself, which of course is not certain - it's unlikely to be worse, though), then compare that to the amount of carcinogenic material inhaled when you smoke burning plant material.
It's not worth worrying about the carcinogenicity if one is smoking in moderation.
Now, the people who smoke 50-100mg bowls of pure JWH-018 several times a day, they should be worrying about it (among the many other side-effects of such ridiculously heavy use).

One definite risk of the JWH's are that they are much less forgiving than cannabis is. Smoking too much pot is rarely a big deal, especially not for an experienced smoker. Smoking too much JWH is much more unpleasant. Some blends have "hotspots", and eyeballing doses of the pure chemicals is obviously imprecise.
The anxiety-filled cannabinoid overdose, while not physically dangerous, can lead to lasting anxiety when using any cannabinoid (check out the threads in cannabis discussion, there are a few people complaining that after a bad experience with a JWH-containing blend, they can no longer enjoy weed). Of course to be fair, there are also people who get bad anxiety on weed, and found that synthetics (at least some of them) do not cause anxiety. Certainly the anxiogenic effects of synthetics vary - JWH-018 is particularly bad.
 
Thanks everyone, and yeah i've overdosed on -018 and it was scary to say the least. I wasnt extremely worried about the carcinogens involved, but much obliged for the information given. I just wanted to know if there was any serious consequence for a recreational smoker...and apparently there isn't much to worry about
 
I think it may reduce lung capacity....only side effect i've found so far through months of usage. tread carefully.
 
TheAzo said:
The "holes in brain" is a rumor. The scare-tactic people throw that one out there for every damned drug.

They're pretty likely to be carcinogenic - any of the ones with the napthyl moiety (with the possible exception of 081, which has an ether linkage on the napthyl - that often makes compounds with the napthyl moiety on them non-carcinogenic). The carcinogenicity would be via the same mechanism that napthalene is carcinogenic - the body doesn't know what to do with this big napthyl group, and resorts to oxidizing it to the carcinogenic epoxide. However, you can calculate out how much of the active component you're getting into your body (not that much) and how much napthalene that would be equivilent to (assuming it's equally carcinogenic as napthalene itself, which of course is not certain - it's unlikely to be worse, though), then compare that to the amount of carcinogenic material inhaled when you smoke burning plant material.
It's not worth worrying about the carcinogenicity if one is smoking in moderation.
Now, the people who smoke 50-100mg bowls of pure JWH-018 several times a day, they should be worrying about it (among the many other side-effects of such ridiculously heavy use).

One definite risk of the JWH's are that they are much less forgiving than cannabis is. Smoking too much pot is rarely a big deal, especially not for an experienced smoker. Smoking too much JWH is much more unpleasant. Some blends have "hotspots", and eyeballing doses of the pure chemicals is obviously imprecise.
The anxiety-filled cannabinoid overdose, while not physically dangerous, can lead to lasting anxiety when using any cannabinoid (check out the threads in cannabis discussion, there are a few people complaining that after a bad experience with a JWH-containing blend, they can no longer enjoy weed). Of course to be fair, there are also people who get bad anxiety on weed, and found that synthetics (at least some of them) do not cause anxiety. Certainly the anxiogenic effects of synthetics vary - JWH-018 is particularly bad.
Click to expand...

Doesn't Jwh-250 also count as an exception, as it is lacking a nathyl group entirely?
 
TheAzo -

Thanks for your post, it sums up my understanding will and adds information to what I knew.

One addition: even if you carefully weigh your JWH-xxx on a milligram scale, there is some residue left in the smoking apparatus. After smoking for several weeks, for example, you can easily get high more than once just by lighting your empty bowl. Therefore, it is possible to get too much by smoking a "regular" bowl but having the residue also vaporized in the same hit.
 
Mholtb said:
Doesn't Jwh-250 also count as an exception, as it is lacking a nathyl group entirely?
Click to expand...

Yes, along with JWH-203, AM-694, RCS-4/8 (Which pharma company is "RCS"?). Note the WIN-48,211 does contain the napthoyl moiety, as does AM-2201.
 
It certainly will not put physical holes in your brain, however there are legitimate concerns regarding the metabolites of the JWH family of compounds. More research is needed.

Also the quality of the JWH material itself has been on a steady decline since roughly late 2007. So unknown impurities are also a factor.
 
We need to really IP ban all the dipshits saying that the naphthoylindole JWHs will kill you with the naphthalene ring. There are numerous (can't recall any now, but there are)medicines that have the naphthalene ring and if any of this hysteria turned out to be cause for concern those medicines wouldn't exist...
In fact I'm 99% sure if anything these fuckups were saying was true, aleve would kill you via cancer.
 
I took jwh 018 for the first time last week. I took 7mg sprinkled in a joint and got pleasantly stoned. Next time I weighed 14mg intending to half it into 2 doses and forgot and put the lot in. For about 15-20mins I felt nervous and then had the most incredidible euphoric experience for an hour or so which then tapered off during the following 2 hours. Next time I weighed 10mg and had the most terrifying experience of my entire like. I`m over 50. I thought I was going to die and was hallucinating visuals like smoke drifting in front of me. I was so convinnced I was going to die I typed a goodbye message to my partner on my mobile and it took 20 mins to type one short sentence. I looked at pictures of this stuff and everywhere I looked it was white but mine was an orangy yellow coulour. What exactly is the reccomended dose? I am sure 7-10mg was well within the safe dose?
 
^ Open a new thread, don't hijack threads that have nothing to do with your question.
 
it's an RC, of course the danger is truly an unknown. proceed with that lack of knowledge.

there are many threads with more information then you ever wanted to know here already, use the search engine
 
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