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Just smoked MDPV before reading about pyrrolidine.

sizzurp

sizzurp

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East Bay Area, California
So a friend and I smoked MDPV and only later did we read about pyrrolidine being a byproduct that is left in MDPV and that's it's harmful to lung tissue.

My question is did this do any long term damage to my lungs. I noticed that it made the pipe nasty and brown. I don't smoke cig's and rarely smoke weed and it would suck to have just done some sort of permanent damage!!!! :(
 
Considering all of the nasty things found in tobacco and how long people live after smoking a couple of them, you should really just relax.
 
I don't think you have much to worry about. I'd strongly suggest not doing it again though. It is extremely addictive in and of itself (damage to lungs notwithstanding).
 
its a joke to be worried about the pyrrolidine impurity which was supposedly found in a concentration of 2-3% in some batches, to make the math easier say 5%, doses around 10mg, so half a milligram on the very outside, it is not worth worrying about that when you have just inhaled 9.5mg of a vapourized research chemical the long term toxicity of which is totally unknown.
 
it is a scary thought. solution - smoke some more PV and think about it some more like a week or so. dont bother sleeping. do rewire the house sound system though.

j/k, one of the safest stims out there. or more dead would walk amongst us...
 
Then you need to smoke more to think about the week you just though about... but you were thinking about sex, so more thinking about sex
 
nanobrain said:
it is a scary thought. solution - smoke some more PV and think about it some more like a week or so. dont bother sleeping. do rewire the house sound system though.

j/k, one of the safest stims out there. or more dead would walk amongst us...
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ridiculously unfounded statement, sorry nanobrain (I love ya but gotta call this one out!)
 
Much less risk than MA especially. I abused mdpv sometime ago and could still feel relatively lucid until night 3, with MA things are horrid after one night ymmv
 
Does pyrrolidine have the same reproductive tox. issues as pyridine?

And MA turns horrid after oh, about a picosecond:P
 
I'm sure the freebase doesn't yield that when smoked. When you smoke the salt I could feel a definate pain on my throat, and around my kidneys/liver aswell as the doapminergenic crackling effect across my scalp.
With freebase it never occurred despite binging for days on it.
Weird.
 
local labrats have been exposed to chronic doses of up to 800mg/d with no ill effects noted, save sexual abberation and an induced severe intolerance for bad sound equipment cables / jacks - unlike the contrlos exposed to MA/ice for similar duration who exhibited a variety of deleterious symptoms. ymmv.
 
>>I'm sure the freebase doesn't yield that when smoked. When you smoke the salt I could feel a definate pain on my throat, and around my kidneys/liver aswell as the doapminergenic crackling effect across my scalp.
With freebase it never occurred despite binging for days on it.
Weird.>>

Do you have any information showing that the freebase doesn't yield harmful breakdown products when vaporized while the salt does, other than the feelings that you get?

ebola
 
Do you have any information showing that the freebase doesn't yield harmful breakdown products when vaporized while the salt does, other than the feelings that you get?

ebola
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I will send a sample off to a chemist friend and get both the freebase impurities and the salt form impurities analysed, then we can look at temperature breakdowns for the relevant structures.

The difference in feeling was one of feeling poisened (head crackling with DA sparkles, noticable pain in throat, lungs, and particularly around the kidneys) or one of feeling absolutely nothing.

Freebase does exist, obviously, even if it degrades insanely fast, procedure used (during binge so can't remember exactly) was bicarb of soda, as small an amount of liquid as possible and a dab of mdpv smeared onto glass and immediately vaped, yielded a far stronger high than a lot larger amount of salt form smoked.

The beautiful "semen" smell was insanely strong, so it would indicate the freebase impurity vapes/decomposes entirely.

That non-aromatic ring is a bastard, time to start sketching.
 
Asked a chemist friend about this, and he said freebase pyrollidine exists as a liquid and smells very strongly of semen. When treated with bicarbonate of soda the MDPV quickly turns yellow (nitrogen, or pyrollidine break down product) and smells incredibly strongly of the aforementioned smell, that, coupled with the subjective effects of the drug, and the heat used to vapourise (and the far smaller amount needed), leads me to conclude that freebase MDPV carries very very little risk of pyrollidine damage in comparison to the snorted, plugged or smoked salt.
 
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It wouldn't 'fit through' the DA transporter. It binds to the transporter and stops it's function. Amphetamine and other 'cascaders' don't even bind to the same receptor- their affinity is for VMAT2, not DAT.

And neurotoxicity does not have to result from toxic metabolites. There are definitely other routes, the parent itself may be neurotoxic, and that seems to be true for just about all stimulants.
 
Umm, I stated it was a pure DNRI (DA:NE, 5:1) and that lowered toxicity. The pyrollidine breakdown product is neurotoxic definately but it isn't present in the freebase when smoked.
 
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Well if you're going to just edit out the comments I'm referring to, you're really not playing fair.

IlostaMadge said:
The compound, being far far too big (and having a double bonded ketone) to fit through a DA transporter should be almost un-neurotoxic due to not actually releasing harmful breakdown products, the idiotic length of that side change must change DAT conformation over time slightly, as many reports have said that is lessens the ability to enjoy amphetamines and other cascaders
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