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Journal Article Wanted (J Med Chem)

S

Sphinx (Afterlife)

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If anyone has access to this or knows of a location online where one can purchase it please LMK

Wang ZX, Zhu YC, Jin WQ, et al.
Stereoisomers of N-[1-(2-hydroxy-2-phenylethyl)-3-methyl-4-peperidyl]-N-phenyloropanamide: synthesis, stereochemistry, analgesic activity, and opioid receptor binding characteristics.
J Med Chem 1995; 38:3652-9
 
How about this, can anyone help?

Brine GA, Stark PA, Liu Y, Carroll FI, Singh P, Xu H, Rothman RB
Enantiomers of diastereomeric cis-N-[1-(2-hydroxy-2-phenylethyl)- 3-methyl-4-piperidyl]-N-phenylpropanamides: synthesis, X-ray analysis, and biological activities.
Research Triangle Institute, Research Triangle Park, North Carolina 27709, USA.
J Med Chem. 1995 Apr 28;38 (9):1547-57

Erratum in:
* J Med Chem 1997 May 9;40(10):1560.
 
[edit]

somehow I got confused and posted the wrong article (which had already been posted by C6H6!)

but here is the second article you requested at last (sorry for the mix-up):

"Enantiomers of Diastereomeric cis-N-[1-(2-Hydroxy-2-phenylethyl)-3-methyl-4-piperidylI- N-phenylpropanamides: Synthesis, X-ray Analysis, and Biological Activities"

http://tinyurl.com/d527b

[/edit]
 
Last edited:
^I'll get it the next time I go in the library unless someone posts it before.
 
Here is the erratum:

Enantiomers of Diastereoisomeric cis-N-[1-(2-Hydroxy-2-phenylethyl)-3-methyl-4-piperidyl]-N-phenylpropanamides: Synthesis, X-ray Analysis, and Biological Activities
George A. Brine, Peter A. Stark, Young Liu, F. Ivy Carroll, P. Singh, Heng Xu, and Richard B. Rothman
J. Med. Chem. 40(10), 1560 (1997)
http://tinyurl.com/dlxoc

also I fixed the link I posted above
 
3-MeF is already extremely potent as it is. Since I am not that intelligent on this could somebody write down a list of generalizations to explain the differences? I could probably find out if I put in the effort but it is just a case of not having the motivation. Specifically i'd like to know how much of an effect the added hydroxy group has. Anyway, thanks for posting this article since I can probably answer my own questions if I put in the time to read it.
 
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