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Iv thc

S

syndeusys

Bluelighter
Joined
Dec 16, 2009
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So I figured I'd give CD a chance...mistake. So i come back to my favorite forum. I have a friend who has told me he has figured out how to isolate THC crystals from weed as delta-9-THC. I have very limited knowledge about active metabolites of THC. However i was wondering if it was possible to use a fairly easy reaction to convert the delta-9-THC to 11-hydroxy-THC. I know providing synthesis breaks rules of the forum so I'm mostly interested as to if it's easily possible, what pathway in the CYP450 metabolizes 11-hydroxy-THC, if there are any inhibitors of that pathway (i assume it's 2C9), the potential dangers/benefits of IV administration of THC, and whether or not its the most effective compound to isolate for recreations sake. If there are any other active metabolites info would be apprecitated as I'm more of a chem/pharma guy. Please pharmacological input only. Thanks in advance
 
There was a thread on IVing THC somewhere on BL. Maybe in CD. Maybe you already know of it.


Also, way long ago, i remember reading a procedure for somehow magically making THC (well, a mixed extract of cannabinoids from weed) more powerful by isomerizing it, the guy described refluxing it with sulfuric acid using ethyl ether as the solvent. I've got no clue if that would work, it was a long time ago that i read it, and it sounds "too easy", and iirc the procedure was written up in a non-professional manner.
 
That youtube video was really interesting.
It explains a lot of why i was mostly having psychotic and depressed reactions back in my weed smoking days.
Never knew that those 2 cannabinoids could act so differently on the same person.
I did believe that every person behaved differently on marijuana for its ability do push underlying feelings and states of consciousness (from euphoria to anxiety) and probably also cause of different levels of receptors, but never thought that this had a lot to do with the ratio of THC and CBD.
 
Under no circumstances should you IV or IM extract from a plant. Someone died doing so with a mushroom extract. You don't want systemic sepsis. ;)

ebola
 
ebola? said:
Under no circumstances should you IV or IM extract from a plant. Someone died doing so with a mushroom extract. You don't want systemic sepsis. ;)

ebola
Click to expand...


That kinda depends on how well it is extracted and purified. Personally, I wouldn't trust anything (for IV) that hasn't gone through column chromatography at least...
 
CBD content has an antispychotic effect of moderating high thc/thcv levels

thus why has is easier high to handele if you have a psychotic disorder (bipolar)
 
That kinda depends on how well it is extracted and purified. Personally, I wouldn't trust anything (for IV) that hasn't gone through column chromatography at least...
Click to expand...

Aye. I just worry for the amateurs, ample with gusto, short on knowledge and experience. . .

ebola
 
flacky said:
http://en.wikipedia.org/wiki/Intravenous_Marijuana_Syndrome
^ Never, ever, ever, ever inject anything except for PURE, LAB SYNTHESIZED, PROPERLY DISSOLVED, PREFERABLY A WATER-SOLUBLE DERIVATIVE cannabinoid.
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You are correct of course, but that link is one of the dumbest wiki pages Ive seen.

The page describes the illness as though there is something unique about marijuana that would cause sever illness if a crude extract were administered via IV. And then they go on to say, "Contamination, perhaps from the cotton used to strain the liquid, was suggested as a cause for the illnesses".

Yea....the cotton strainer was likely the cause of the illness. Im sure it had nothing to do with the fact that people were injecting a crude plant extract. Immune systems don't like random plant proteins being injected directly into the bloodstream-they tend to interpret it as an attack on the system.
 
^ People didn't have the same problems with injection of crude opium extract. That's why it is specific to marijuana.
 
flacky said:
^ People didn't have the same problems with injection of crude opium extract. That's why it is specific to marijuana.
Click to expand...

Because you are referring to a crude extract of the latex ONLY.
If someone were to make an opium extract by soaking the whole pod in water, and then injecting that, they would experience they exact same symptoms as those of the people who injected marijuana extracts (or any other plant extract for that matter).
 
daddysgone said:
Because you are referring to a crude extract of the latex ONLY.
If someone were to make an opium extract by soaking the whole pod in water, and then injecting that, they would experience they exact same symptoms as those of the people who injected marijuana extracts (or any other plant extract for that matter).
Click to expand...

The latex still contains all kinds of shit that your body doesn't want in it. That's irrelevant.
 
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