N&PD Moderators: Skorpio
IV melatonin
LucidShroomDmtier
Bluelighter
since melatonin cross BBB,it would probably have some psychoactive properties if iv'ied (f.e instant sleepines) and the delivery of antioxidant activity would be very fast delivered and it would be more economic since no expensive melatonin would be broken down during digestion .. the question is if its possible to do so and if its dangerous
Lightning-Nl
Bluelighter
I can see why someone like this would put this in the "Drug Studies" category.
Jesusgreen
Bluelight Crew
Drug Studies -> ADD
I'm not sure if this is really advanced enough for ADD, so do as you will ADD mods.
On the subject I found this: http://bja.oxfordjournals.org/content/90/4/504.long
My question is why would you choose melatonin for this? If you're looking for sleep induction stronger than oral melatonin then maybe looking to other things like kava or benzodiazepines would be more appropriate. Just my 2c.
ebola?
Bluelight Crew
Sublingual and oral administration seem fine, and people haven't discovered clear psychoactivity at any dose (beyond drowsiness and increased dreaming). This issue seems quite clear cut and less than advanced. Maybe a reply soon to come will compel me to keep this open.
ebola
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pofacedhoe
Bluelight Crew
normally when i drink i find it hard to stop until i'm drunk.
with melatonin one drink is satisfying. i dont get an alcohol comedown (the worst of all the comedowns, hence why you get drunk and sleep through it). it seems to curb my addictive greed.
as a drug on it own... nah
sekio
Bluelight Crew
Except it doesn't actually produce psychedelia when administered in high doses. Oops.
High doses of melatonin can cause all sorts of wierd regulatory problems anyway.
'medicine cabinet'
Bluelighter
^yea my old dr gave me a few samples of that crap. chamomile tea is a better sleep aid lol.
Yup. Dr. Rick Strassman ran some crazy mega-dose melatonin experiments before diving into DMT land. People basically just couldn't stay awake -- nothing spectacular.
Epsilon Alpha
Bluelighter
I took 300mg of melatonin orally once, slept like a baby in the midst of a sleep disorder flare up. I accidentally the whole bottle...
But, yeah nothing to write home about in any case.
Dmt: the spirit molecule was a great read. But no, melatonin provided no psychedelic effect in high doses.
I'm melatonin dependent now, best method to ingest for faster onset is sublingual.
Psychedelic Jay
Bluelighter
What about melatonin’s uncanny ability to calm down bad trips?
In particular potentating tryptamine trips?
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sekio
Bluelight Crew
Is this a thing?
ebola?
Bluelight Crew
Psychedelic Jay said:
I'm not quite understanding this. Are you saying that melatonin attenuates or potentiates psychedelic drugs?
ebola
I once took a super high dose of melatonin, think epsilon alphas post, and experienced very weird dreams as well as a violent temper the next day.
Psychedelic Jay
Bluelighter
Not really in a sense make them stronger, but it definitely attenuates more vigorous trips and turns down the anxiety just a hair without losing many dynamics.
It seems to attenuate a lot of stimulants, and hallucinogens...
I’m reading trip reports from various sources on google from other forums about supplementing
BlueHues
Bluelighter
Last night it was smoking quietapine, now we're on to main-lining melatonin? All we need now is thread on plugging valerian extract! Which may actually work better than drinking it, but I'm personally not planning on breaking out the turkey baster and the Vaseline anytime soon!
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Limpet_Chicken
Bluelighter
Valerian does appear to be active via that route.
(FYI, the reason for that mode of administration, was severe vomiting at the time, nothing would stay down for long)
BlueHues
Bluelighter
Which is perfectly legitimate in those circumstances! I'm all about pragmatism and efficiency...cost-effectiveness, but some of the things people are trying just defy logic!
