is methadone plugable?

[Hydroxymorphodone]

I assume it is, but I figured I would ask since its not an opiate and it burns like hell up the nose...
Also, if it is would it hit harder in the ass?

 

[pallidamors]

I assume it is, but I figured I would ask since its not an opiate and it burns like hell up the nose...
Also, if it is would it hit harder in the ass?

by "not an opiate" do you mean "not derived from the P. somniferum plant"? Because it's a full mu-opioid agonist, therefore, an opioid. But it is synthetic and therefore not derived from any natural alkaloids.

Methadone is water soluble, so yes, you can plug it. Presumably it would be more effective than snorting it since your rectum has more capillaries than your nose.

 

[Hydroxymorphodone]

Thank you for the clarification. I was under the assumption it was not an opiate simply because it does not show up on a drug screen as an opiate.

 

[pallidamors]

Thank you for the clarification. I was under the assumption it was not an opiate simply because it does not show up on a drug screen as an opiate.

that's because it has a different chemical structure than natural and many semisynthetic opioids, and those tests are designed to detect certain metabolites with structural similarities if i'm not mistaken. so its not an opiate, just because of its structure, but it is an opioid, because it has the function of binding opioid receptors. does that make sense?

 

[Hydroxymorphodone]

that's because it has a different chemical structure than natural and many semisynthetic opioids, and those tests are designed to detect certain metabolites with structural similarities if i'm not mistaken. so its not an opiate, just because of its structure, but it is an opioid, because it has the function of binding opioid receptors. does that make sense?

Yes, that makes sense. So its like suboxone, because it binds the receptors, but it does not have a "ceiling" on how high you can get?