Is it safe to mix Benzos + Diphenhydramine?

[pally pete]

About 7 hours ago i took 100mg Diazepam (As many of you know i have a massive Benzo Tolerance)

Its now approaching bed time and im still feeling quite anxious and worrying about not getting to sleep, i most definately do not want to take any more Diazepam if i can help it, but saying that i have around 6-8mg of Alprazolam which perversly i am tempted to take (maybe because i find it slightly more sedating than Diazepam) I also have some 50mg Diphenhydramine tabs.

Now is this a safe combo taking into account my benzo tolerance?

Also would 1 pint of 4.5% cider cause me any harm? Other than Potentiate the other meds?

As far as my Benzo abuse is going my levels have come down considerably even though im trying to taper from them in a very unorthodox way.

I use Diazepam on average 1-2 times per week only when i feel desperate and my withdrawals are unbearable/boardering on dangerous! Each time i dose with Diazepam i use the bare minimum that will slighly ease my withdrawal symptoms which is 100mg

Thanks Bluelight.

 

[Pjkt2501]

I would use the Diphenhydramine if it's possible to get to sleep. Maybe the can of cider, but even then I don't fully condone it at the level diazepam you have in your system.

Good luck mate.

 

[pally pete]

Thanks^^^^

One more question, apologies if this is the wrong section or if i should start a new thread.

But my Psychiatrist/G.P will have prescribed me varying doses at different times over the past almost year now of Citalopram, Sertraline and Venlafaxine, none ofwhich have worked at all, in fact as feel as bad today, if not worse (eg i have much more suicidal thoughts, almost daily crying spells) than i did this time last year, ive informed my Psychiatrist (Who discharged me after one 1 hour interview/appointment!) Ive also informed my G.P and neither of them seem to show any level of understanding or suggestion of how i can move forward even though i constantly research things and make suggestions to them.

They seem to blame all my problems on my previous Benzo use even though i have explained to them ive been suffering with severe Anxiety/Depression for 15 years and i only discovered Benzos 3 years ago yet they dont want to listen and just seem to switch off!

Ive suggested Agomelatine now that i have come off all the other Anti-Depressants as they didnt work, yet they tell me they can not/ will not prescribe me Agomelatine as it is highly Contraindicated with Benzo yet i have found no evidence of this. Somebody please correct me if im wrong?

My G.P has said there is nothing she can do for me and there are no medications she can prescribe until i have been completely clean of Benzos for 6 months, is this true?

My G.P and Pychiatrist have washed there hands of me and tell me that the only people who can help me is my local drug councilling service which i have been going to since August 2011 (9 Months) and they have not helped me in anyway, apart from talk to me every 2 weeks about exactly what they spoke to me about 2 weeks previously!

They are also great at suggesting things each session i have with them with regards to treatment/tapering plans/sending me to detox etc etc but never ever following through on what they are going to do.

Please help.

 

[bindingaffinity]

The NHS website seems to indicate that agomelatine would only be contraindicated with benzos if they messed with cytochrome P450. Also there's at least one case report in the literature of agomelatine being used to wean someone OFF benzos, although unfortunately I can't access the full text or even the abstract online I could try to see if I could find it in a library for you. But it sounds like your GP and psychiatrist don't know what they're talking about w.r.t. drug interactions. Is Rozerem (ramelteon) available to you? Because it's very similar to agomelatine in mechanism of action, and has no known contraindication with benzos.

 

[pally pete]

The NHS website seems to indicate that agomelatine would only be contraindicated with benzos if they messed with cytochrome P450. Also there's at least one case report in the literature of agomelatine being used to wean someone OFF benzos, although unfortunately I can't access the full text or even the abstract online I could try to see if I could find it in a library for you. But it sounds like your GP and psychiatrist don't know what they're talking about w.r.t. drug interactions. Is Rozerem (ramelteon) available to you? Because it's very similar to agomelatine in mechanism of action, and has no known contraindication with benzos.

I can suggest it but the chances are almost zero of my clueless G.P prescribing it to me.

What i really need is something that will truely help with my Anxiety and Depression, all my G.P has tried me on is 2 SSRI's and 1 SNRI and has given up and told me there is NOTHING else she can do for me.

 

[spini4]

Find a new doctor and go get a second opinion....It's doctors like these standing there with there dicks in there hands that don't do shit to help someone in fear of addiction or other pathetic reasons make me sick. Why even bother being a doctor?

 

[Pjkt2501]

^To be honest I'm with spini.

pally, try a new doctor, and a new psychiatrist. The current ones have literally TOLD you that they're doing nothing for you. Zero reason to go back for another visit (in my opinion).

 

[bindingaffinity]

Wait, all she's tried are two SSRIs and an SNRI? That's pretty terrible. First, find a new doctor. Second, try getting atypical antidepressants (bupropion, mirtazapine, trazodone, etc)---they often work where SSRIs/SNRIs don't.

 

[pally pete]

This may sound very dumb, but i have my next G.P appointment on Wedneday 25th April, im a nice person (Too nice for my own good at times) And im in 2 minds about how to approach this without hurting the feelings of my G.P.

I either tell her that i do not believe she is doing her job correctly and therefore i am going to make an official complaint. (Which is the option i really do not want to take) Especially as she seems a nice person.

Or i go to see her alone (Or maybe with a Famly member or close Friend for backup and the fact that they know me well and are witness to the person i project, as much as they can't see inside my head) And i explain that im at my the end of my teather and apart from the almost daily suicidal thoughts and crying spells (Which she already knows about!) I am actively thinking about pysically harming other people in society, and my suicidal thoughts have progressed into actual detailed suicidal planning.

I am not a liar (Infact as well as being too nice a person i am at times too much an honest person) I am aware that actively thinking about pysically harming other people in society, and my suicidal thoughts having progressed into actual detailed suicidal planning is 'The smoking Gun' which will ring alarm bells and get me fast tracked, so i say this not for the purpose of being fastracked but due to the very fact that what i have written is the truth and i am not lieing or attention seeking.

I am genuinely worried, as for one i am not a violent person, im 32 years of age, the last fight i can remember having was when i was about 16 years of age, infact since that age i have actively avoided conflict at any possible chance. In my words (And words that im sure many will be familiar with?) 'I couldn't fight my way out of a paper bag '

Dont get me wrong, at times i am full of Anger/Rage but this is introverted, where i get angry at myself for feeling the way i do and having no answers for it or no explanation and my mental illness just does not seem to add up.