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Misc Is it safe to IM Promethazine?

Crankinit

Bluelighter
Joined
Sep 17, 2007
Messages
6,175
Hey guys, I seem to end up getting really bad nausea every other time I take opiates, usually I dose promethazine beforehand, but if it wears off while I'm high or the dose isn't high enough, I'll end up throwing up all over the place, which obvious makes it hard to eat another pill of promethazine. I was thinking about maybe IMing the promethazine instead, meaning I'll get much faster relief and won't have to worry about vomiting the tablet back up.

Is there any reason this would be dangerous, or a bad idea? It sounds perfectly safe to me, but I figured I'd check before trying it.

Thanks :)
 
Well since typically IMing or IVing a substance will decrease its half life in total, I highly doubt this will help. Basically it'd probably lose effect even faster leaving you with the same problem and more hassle.

What's your tolerance like? Are you just dosing too high or is it just a weird thing that happens to you with opes?
 
I wouldn't IM promethazine unless you have an ampule version of it, or are micron filtering.

If you are micron filtering, or using an ampule, then it would be safe to IM promethazine, just do not IV promethazine.
 
Well since typically IMing or IVing a substance will decrease its half life in total, I highly doubt this will help. Basically it'd probably lose effect even faster leaving you with the same problem and more hassle.

I know it'll reduce the half life, the point is that it means I can redose for much faster relief and not have to worry about throwing up the tablets.

What's your tolerance like? Are you just dosing too high or is it just a weird thing that happens to you with opes?

I have a fair tolerance, 160 - 200mg of oxy oral, 100 - 120mg or so of morphine IV'd. It's not a question of dosing too high either, it happens even if I lower my dose a bit, just one of the side effects from opiates I seem to be especially prone to.


I wouldn't IM promethazine unless you have an ampule version of it, or are micron filtering.

If you are micron filtering, or using an ampule, then it would be safe to IM promethazine, just do not IV promethazine.

yeah I'm using a micron filter, no way I'd try and shoot a pill without it :| Fuck that.

Not that I'm planning on trying, but outta curiosity why shouldn't I IV promethazine?
 
Antihistamines can cause vein collapse and damage in general. I suspect it will also cause hemolysis.

The antihistamine is a lot more likely to cause vein collapse if you miss part/all of your shot.

It also causes a burning sensation, so it isn't pleasant.
 
...... just do not IV promethazine.

I have IV'd promethazine four or five times. Just cut off pill casing, crushed fine, water and boosted. (I know i should mirco filter ideally).

Apart from the general problems from booting pills, what are the specific issued caused by IV promethazine?

edit: - sorry, somehow missed above reply
 
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Antihistamines can cause vein collapse and damage in general. I suspect it will also cause hemolysis.

The antihistamine is a lot more likely to cause vein collapse if you miss part/all of your shot.

It also causes a burning sensation, so it isn't pleasant.

Ahh interesting, that doesn't sound fun :| I'll stick to IMing. Cheers for the info :)
 
No problem.

You can get away with injecting an antihistamine IV however if you keep doing it long enough and often enough, I would eventually expect to lose a vein that way.

I used to inject hydroxyzine, and realized this before I had done any long-lasting damage. I seem to remember when I was doing this I could only use 2.5 to 5 mg of hydroxyzine IV with only slight stinging. Using more than that in a single shot is very problematic compared to a smaller dosage.
 
No problem.

You can get away with injecting an antihistamine IV however if you keep doing it long enough and often enough, I would eventually expect to lose a vein that way.

I used to inject hydroxyzine, and realized this before I had done any long-lasting damage. I seem to remember when I was doing this I could only use 2.5 to 5 mg of hydroxyzine IV with only slight stinging. Using more than that in a single shot is very problematic compared to a smaller dosage.

I'll just stick to IMing, save my veins for the drugs that actually get me high :p
 
I'll just stick to IMing, save my veins for the drugs that actually get me high :p

=D hahaha exactly.

When I was IVing hydroxyzine, I was combining it with buprenorphine, and only for mild anxiety relief/mild potentiation. It was a considerably decent effect however, it is nothing like using a benzodiazepine. I don't encourage anyone to begin IVing antihistamines, and especially encourage people to avoid it if they aren't using a micron filter.
 
I am fairly sure that Promethazine even in the injectable amp form can be very dangerous to IV or IM. I will due some searching but if I remember correctly it has been responsible for many amputations and may even carry a black box warning.

I know one time I was given an IM shot in the ass in the hospital and that shit hurt for like 3 months. The cheek became somewhat red, warm to the touch and swollen.

I know for sure that it can cause veins to collapse very easily if not injected properly
 
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