Basically, would it be hypothetically possible to take so much of a psychoactive substance of some kind that you forget that your even on anything. Also, has anyone experienced this? I personally have a lot of experience with different stuff and it never happened to me but a friend told me that he knew this guy who took a couple of doses of acid and it happened that he didn't even know he was tripping for a while. I would not have thought this would be possible because it would seem that even the depths of the unconscious would still be aware that drugs were ingested. I find this a strange, yet interesting story. Also, is this something that often happens when one completely "breaks through" (e.g. a dmt/salvia experience)? I could see it as being possible, but something still tells me you'd know you were on something even if it just took you into another world outside of this one and you didn't even know you were in a room or anything, it seems like the fact that you took drugs would be about the last thing to go, but maybe I'm wrong