Hi I hav beeen wanting to try Ecstasy really bad lately but I have heard so amny bad things about it (depression, confusion, memory loss, etc.) Are all of these true?
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depression, confusion, memory loss, etc. can be caused by using mdma but it happens more often to people who are heavy users of the drug. Most occasional users of ecstasy make it though the experience without serious side affect's. However some unlucky user have a genetic pre disposition to depression or Mania or schizophrenia and end up needing prescription medications like anti-depressants or anti psychotics for life due to drug use. But take it from me it's not the end of the world if you end up on medication life goes on and when your older and over taking pills you will more than likely look back and say at least you had fun.
Sadder in what way?
Anxiety and depression probably resulted from my usage with MDMA; just in general my emotions got a lot more intense since I started taking MDMA for better and worse. I did abuse it very heavily though with a bunch of other drugs though. YMMV, with responsible use MDMA will probably change your life for the better and make you a happier more open person.
I wouldn't personally take it and I don't get it why people compare MDMA to cannabis as if they were the same because they certainly aren't.
MDMA (even the pure form) is neurotoxic and cardiotoxic, this means that if you're unlucky and have a heart condition you don't know about you can actually die from a normal dosage.
Plus there are all the negative psychological effects of taking it as you mentioned (depression, confusion and lethargy) for the next following days.
If you want to have fun safely take prescription drugs, at least you know what you're taking (dosage) and you know that it isn't laced with toxic chemicals.
Neurotoxicity? Cardiotoxic? Evidence please?
You are aware that the Ricaurte study this was based on was retracted because he 'accidentally' used crystal meth in the tests instead of MDMA? There are much more recent studies that haven't been able to find bonafide neurotoxicity. This is a good summarizing article to read. Note that they injected these rats with 10-20mg/kg of MDMA (700mg-1400mg at once for someone weighing 70kg) multiple times a day for days in a row in these tests. This helps put the results into perspective even morehttp://www.nature.com/npp/journal/v10/n2/full/npp199415a.html
A drug which completely depletes your serotonin and strongly affects the dopamine release cannot have positive effects on the brain, I'm happy for you if you don't have any problems the day after rolling.
And do I really need to post evidence that MDMA is cardiotoxic?
The example I used with cannabis intended to underline how some ignorant people compare MDMA to weed just because ecstasy has a slight psychedelic effect.
But yeah my post was HR, there are numerous studies which show how benzos and pharmaceutical opiates (excluding Oxy) are physically safe. Obviously this doesn't mean that they can't cause problems (they certainly DO if misused and can ruin your life), but an occasional or sporadic use of both substances has no negative psychological or physical impact unlike MDMA. Plus most of the MDMA you find in the clubs is not even MDMA but a mixture of RC's, pseudo ephedrine and crushed caffeine pills.
There are also numerous posts here on BL of people who suffered months of depression, crippling anxiety and panic attacks after rolling one single night, this simply doesn't happen with pharm opiates or Benzodiazepines.
Therefore I was simply proposing a better alternative if he wanted one, I didn't say that he MUST use prescription drugs because it would obviously be best not to use drugs at all.
Results
MDMA is a substrate for monoamine transporters, and stimulated release of 5-HT, NE, and DA mediates effects of the drug. MDMA produces neurochemical, endocrine, and behavioral actions in rats and humans at equivalent doses (e.g., 1–2 mg/kg), suggesting that there is no reason to adjust doses between these species. Typical doses of MDMA causing long-term 5-HT depletions in rats (e.g., 10–20 mg/kg) do not reliably increase markers of neurotoxic damage such as cell death, silver staining, or reactive gliosis. MDMA-induced 5-HT depletions are accompanied by a number of functional consequences including reductions in evoked 5-HT release and changes in hormone secretion. Perhaps more importantly, administration of MDMA to rats induces persistent anxiety-like behaviors in the absence of measurable 5-HT deficits.
Conclusions
MDMA-induced 5-HT depletions are not necessarily synonymous with neurotoxic damage. However, doses of MDMA which do not cause long-term 5-HT depletions can have protracted effects on behavior, suggesting even moderate doses of the drug may pose risks.
Personally, i hate MDMA comedowns (or the days following taking it).
So i don't take it - because for me, at least it isn't "worth it" for the high.
My relationship with alcohol is similar, but i would be more open to taking MDMA than alcohol.
I always loved LSD and thought MDMA was kind of empty hedonism.
That's what some people love about it
But to me its always felt like i "pay for it" later, rather than have a contented, acid-fried afterglow...
Each to their own.

I remember enjoying the first day after MDMA having a pleasant afterglow, like you say.Interesting, for me the afterglow of MDMA and LSD are quite similar, a fried afterglow like you describe, content to just stare at a wall for hours with a smile plastered across my face if need be. Some people are more sensitive to after-effects than others sadly. I only get something else than an afterglow if I went on a binge, took waaay too much, combined with other drugs or something like that. It also doesn't feel simply shallow and hedonistic to me, I've become a better person because of this drug. I do agree LSD has a lot more depth to it though. Always interesting to see how much drug experiences an appreciation can vary between people :D
For me it lasts a few days (2-3 usually) and then fades away. I usually don't get any negative after-effects unless there's a reason (not enough sleep, too much caffeïne, too high dose,...). I realise I'm rather an exception though. I experienced horrible after-effects for a month or two once, but that was when I really went waaaaaaaaay too hard. Apart from that one time, always positive with tested MDMAI remember enjoying the first day after MDMA having a pleasant afterglow, like you say.
It was the couple of days after that which felt a bit rough.![]()