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Intravenous crude marijuana prep with nothing but alcohol vs alcohol + other stuff

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red22

red22

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This is an intravenous THC preparation:

The injection solution consisted of 0.1% (w/v) of THC, 1.5% (w/v) Tween® 80, 5.0% (v/v) ethanol absolute, 0.1% (w/v) sodium ascorbate, and sodium chloride solution (0.9%).[16] Sodium ascorbate was added to prevent the oxidation of THC to cannabinol. THC was dissolved in ethanol and Tween® 80, then added to the sodium ascorbate dissolved in 1 mL of the sodium chloride solution. The remaining sodium chloride solution was finally added to the mixture. The clear, yellowish solution was then sonicated for 30 s and filtrated through a 0.22-m filter under aseptic conditions

source

Now, an individual has reported to have intravenously injected hash multiple times using nothing but either ethanol or isopropyl alcohol. This individual has only give the details for one of the instances. He claims to have mixed .01cc - .05cc of hash into .1cc - .2cc of 99% isopropyl alcohol. He notes "everclear and 151 worked just as well, but burned more." The individual then proceeded to intravenously administer the hash.

source

OK, so that professional IV THC formula at the top, there's three ingredients in addition (not counting the THC) to an alcohol. Tween® 80, sodium ascorbate, and sodium chloride solution. My question is what is the benefit of using those extra ingredients? The individual who tried shooting hash apparently didn't need them.

How hard would it be to reverse engineer that IV THC formula or do you think that it would be possible to obtain that recipe or a suitable alternative?
 
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Jesus-fucking Christ. I recall a discussion I had via PM with a member about this and the conclusion is that unless you have a lab to isolate pure THC you shouldn't fuck with IV prep of it. Most people "shooting hash" are not going to go through the prep work needed to get a clean, emulsified shot when you can just burn the stuff. There's a "marijuana injection syndrome" similar to cotton fever that some people get from shooting boiled weed broth (in water), and it's not pleasant.

Ethanol and isopropanol, administered IV (also things like vodka and everclear), are very destructive to venous tissue. This is why the "professional" injection uses Tween and only 5% alcohol. I won't elaborate why but suffice to say solvents and veins are incompatible most of the time.

The sodium ascorbate is just an antioxidant to prevent decomposition of the THC. Tween 80 is commonly known as polysorbate 80 and acts as an emulsifying agent. The sodium chloride is there to adjust the salinity. Also of note is the use of pure isolated THC & micron filtering.

I cannot reccomend injection of THC because vapourisation is just so much easier and safer. If you do want to experience IV cannbinoids I would attempt a chromatographic isolation and get sterile equipment and reagents before I loaded a syringe. There's no reverse-engineering needed - you posted a good recipe.

Your friend who is injecting raw hash in absolute alcohol is doing an immense amount of damage to his veins, and running the risk of embolism and contamination.
 
sekio said:
There's no reverse-engineering needed - you posted a good recipe.
Click to expand...

But it only gives percents. If I order all those ingredients off the Internet with the intent of applying the formula to hash, how am I going to know the amounts to mix?
 
This thread is making me laugh my ass off! Please tell us how it ends up if your not dead:):):)
 
Can someone please give me instructions on how to recreate that THC emulsion? And, once again, I will be applying the emulsion to hash, not THC isolate. I have no interest in isolated cannabinoids and do not wish to discuss them in this thread. I am specifically interested in injecting crude marijuana.
 
Seiko pretty much captured it: the risk of embolism or systemic bacterial or fungal infection is far to dangerous with extractions and emulsions this simple. Don't do it if you care about whether or not you stay living.

ebola
 
sekio said that the recipe does not need to be reverse engineered. The percent indications are sufficient for an amateur to literally weigh, mix, and recreate the emulsion? Is that correct?
 
If you are really that dedicated to doing this safely you need to do the following.

1. Get a lab, solvents, chromatographic column, rotary evaporator etc.
2. Get hash oil, isolate THC via some literature method (look up US patents).
3. Sterilize via irradiation (UV or gamma) all your reagents & equipment.
4. Prepare the shot & inject in a sterile room with the appropriate safety precautions (alcohol swab etc.)

You likely don't have access to this equipment, nor do you have the skills needed to prepare the required ingredients... Substitution of hash for THC is not an option because of hash's huge insoluble particulate content & significant percentage of inactive and possibly allergenic compounds.

I am specifically interested in injecting crude marijuana.
Click to expand...
There's no hope for you. This is equivalent to saying 'I am interested in directly injecting Percocets, can someone help?' - it's not something that can be discussed on a harm reduction forum aside from the option to not do it.
 
This isn't making me laugh at all.

Umm... You know that "crude" is gonna be a bacterial and fungal mess, right?

This really isn't an appropriate substance to inject. Honestly, there is absolutely no way to make this even "safer-ish"- That's why nobody wants to help. It's Russian Roulette with five cylinders loaded.

Please reconsider.
 
You don't want to inject crude plant matter. There are proteins and histamines that can cause you to go into shock and die.

You could make a clean extract from hashish given the recipe above, and with some knowledge of the different ways to sterilize plant extractions, different types of wheel filters, what size you would need to ensure all proteins are removed, etc...you could get away with making an inject-able cannabis solution.

But if reading what you posted is not enough to get you going...then you are not knowledgeable enough to be attempting it my friend. Take a car...you can buy that book for any car that gives you instructions on how to change/fix anything. But without sufficient knowledge of the tools used, how certain procedures are carried out, etc....you call a mechanic don't you? Well I would anyway, my car is too expensive for me to go fucking with it..especially when it's actually the banks car...they just let me drive it.

If someone else wants to write you more detailed instructions on how to potentially kill yourself with marijuana...they can but I would just forget it...it's just the truth as I see fit to print.
 
red22 said:
He claims to have mixed .01cc - .05cc of hash into .1cc - .2cc of 99% isopropyl alcohol.
Click to expand...

a subtle detail is that your friend is talking about a volume of hash oil, not hash.

still sounds less than wise
 
rhizome said:
This isn't making me laugh at all.

Umm... You know that "crude" is gonna be a bacterial and fungal mess, right?

This really isn't an appropriate substance to inject. Honestly, there is absolutely no way to make this even "safer-ish"- That's why nobody wants to help. It's Russian Roulette with five cylinders loaded.

Please reconsider.
Click to expand...

It's not funny anymore because he might be seriouse :(
 
People do stupid things. We have advised him against it, tried to make him see how dangerous it its, told him the extent of what would be necessary to do this safely and even given him an idea to make what he is talking about less danergous if he ignores warning and chooses to proceed. Im afraid we cannot do much more.
I dont mean to be harsh but if he does it and doesnt survive we can look to Darwins theory of evolution for comfort.

On a related note have there been any reports of people injecting any of the synthetic cannabinoids before?
 
I wonder if Dronabinol gel tabs could be IV'd if properly prepared.

I shot micronfiltered (at .22) marijuana broth; of course it not being readily water soluble I felt nothing. I plugged cooking oil in which marijuana buds soaked, and got a much better effect. I don't have much experience smoking cannabis in all honesty, I was just doing to be 'unconventional', but this latter route give me the oft mentioned "munchies" in an instant & extreme fashion. Are their cannibinoid receptors in the intestinal tract like there are opioid receptors?
 
The problem with THC and friends is that they are just not water soluble enough to warrant IV usage. Even Dronabinol tabs are dissolved in sesame oil, not water. The IV preparation uses a very low THC concentration and lots of emulsifier to help the solution remain in one phase - otherwise upon adding water you'd heva cloudy, lumpy, salad-dressing type thing that's going to hurt to inject.

Plugging cannabis & extracts would work because the rectum has a good percentage of fatty tissue and it can adsorb the fat-soluble cannabinoids easily. The disadvantage is, well, putting plant material in oil up your butt. Kind of messy. There are perhipheral cannabinoid receptors (CB2) but I think most of the effect is produced from THC hitting the brain.

There are definitely reports of people injecting other synthetic cannabinoids. There's a couple that were designed specifically to raise the water solubility. I don't think things like the JWH series are soluble enough to warrant injection either, though.
 
So what does banging hash feel like? I almost did it one but cooler heads prevailed.
 
On this other site...Synapse (or mad sci?) has a report involving one of the WIN compounds, IIRC...and I THINK he said it was like a supercharged bong-hit but less sedating.
 
Sekio, some of the JWH's should be water soluble (as salts) like JWH-200 (WIN-55,225). But yeah, it's probably faster, slightly more potent, and totally not worth it. (Unless you're injecting pure material, then I don't see a problem)
 
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