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BDD Moderators: Keif’ Richards
Instanyl (fentanyl intranasal) opinions and guidance
- Thread starter j0hn0b
- Start date
I've looked for a while and have not been able to find a dosage comparison between this and the other ROAs for fentanyl. I would proceed very cautiously until you or someone else can accurately procure this information.
There is recreational value there, but you need to be sure you get a safe dose. What is your tolerance like to other opiates / opioids? I'm very hopeful that someone else can shed some more light on the dose comparison, and then the two pieces of information can be combined to gauge a reasonably safe starting dose.
Until then, I'd stay on the safe side and put it on hold.
There is recreational value there, but you need to be sure you get a safe dose. What is your tolerance like to other opiates / opioids? I'm very hopeful that someone else can shed some more light on the dose comparison, and then the two pieces of information can be combined to gauge a reasonably safe starting dose.
Until then, I'd stay on the safe side and put it on hold.
I have low to moderate tolerance for opiates is it is. The spray I have is 50ug/spray which is the lowest one that they make. I was thinking about possibly diluting it further to with USP Saline to test effects. I haven't had fentanyl in the past in any ROA, but I have experience hydromorphone, oxycodone and hydrocodone. The bottle has 110 50ug doses, and it's not going anywhere. I'm scared about my tolerance level and if I'd be able to enjoy the experience at all currently. Until I know more I'm holding off anyway.
Cane2theLeft
Bluelight Crew
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It's right on fentanyl's wikipedia page.
Bioavailability
92% (transdermal)
89% (intranasal)
50% (buccal)
33% (ingestion)
92% (transdermal)
89% (intranasal)
50% (buccal)
33% (ingestion)
Google also produces several sources confirming 89%. Where were you looking exactly?
That I could find, but it still leaves tricky dosing questions, as many of the other ROAs are time released to different degrees, whereas internasal would be more immediate. Thus, I don't think it's a safe assumption that just because the doses (factored with the bioavailability) are equal that the same strength high would be produced.
Whenever it comes to anything fentanyl related, I tread with extreme caution.
Whenever it comes to anything fentanyl related, I tread with extreme caution.
Well honestly I don't take much hydromorphone... usually 4-6 and I'm happy. 8 is a little much. I have mainly stuck with hydrocodone/oxycodone due to availability. The deal for the fentanyl was extremely good, strangely enough it was cheaper than any other option which is why I jumped at it.
It probably has to due with the fact that some people (myself included) don't get much euphoria out of fentanyl. It is more of just a plain sedation feeling withou the euphoria commonly associated with opiates. Anyway man I'd be wicked careful, messing with fentanyl without a solid opiate tolerance is a dangerous game.
Yeah I'm not sure that I will take it. I might try to dilute the 50/mcg dosage to half that and see what happens. 12.5mcg can't really do too much damage I don't think as far as I can tell. Anyway I have access to Narcan as well if things go real far south quick, which could help.
Wait are we talking the 4-6mg hydromorphone orally or IV? If you can eat 4mg of hydromorphone and feel anything, do not go anywhere near fentanyl.
So is it oral or IV were talking? We need more info..
And narcan is useless unless you have a knowledgable friend with a clean rig nearby. If you need narcan, chances are you won't be able to administer yourself.
So is it oral or IV were talking? We need more info..
And narcan is useless unless you have a knowledgable friend with a clean rig nearby. If you need narcan, chances are you won't be able to administer yourself.
Doctor_Ew420
Bluelighter
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I don't even think narcan would do anything for a fentanyl overdose that could be life threatening.
This is a harm reduction site, it IS good that people are incredibly cautious, but, fentanyl gets some kind of special attention simply because it is so potent. What you have is pharm grade 50mcg intranasal fentanyl and even with your low tolerance, 1 shot shouldn't cause a problem.
Honestly, I would suggest 2 if I knew that you were in a safe setting (like a hospital) but I don't. If the OP meant that 6mg of hydromorphone is manageable as an oral dose, I would certainly say that starting with 1 shot up the nose without other drugs active should cause a nice sedation. Don't be too freaked out, fentanyl makes even seasoned opiate users puke for their first time. Be careful. Good luck.
This is a harm reduction site, it IS good that people are incredibly cautious, but, fentanyl gets some kind of special attention simply because it is so potent. What you have is pharm grade 50mcg intranasal fentanyl and even with your low tolerance, 1 shot shouldn't cause a problem.
Honestly, I would suggest 2 if I knew that you were in a safe setting (like a hospital) but I don't. If the OP meant that 6mg of hydromorphone is manageable as an oral dose, I would certainly say that starting with 1 shot up the nose without other drugs active should cause a nice sedation. Don't be too freaked out, fentanyl makes even seasoned opiate users puke for their first time. Be careful. Good luck.
VanWeyden
Bluelighter
Narcan will surely reverse a fentanyl overdose. It is a regular full antagonist with an extremely high potency but a smaller affinity to the opioid receptors as naloxone. In clinical setting naloxone is regularly used to block fentanyl in clinical settings (anesthesia etc.). However it has to be administered intravenously.
You should be fine working your way up slowly. Fortunately fentanyl is absorbed quickly via the intranasal route, which makes it a lot easier to dose than fentanyl patches. One 50mcg shot is equivalent to ca. 1mg intravenous, 2mg insufflated or 3-4mg oral hydromorphone ir.
In case one shot isn't enough, wait 2-3 hours and then apply 2 shots, but don't go any further. Although the half life and duration of action is short, it is context-sensitive (the more and longer it is applied, the longer the half life becomes) and therefore difficult to measure.
You should be fine working your way up slowly. Fortunately fentanyl is absorbed quickly via the intranasal route, which makes it a lot easier to dose than fentanyl patches. One 50mcg shot is equivalent to ca. 1mg intravenous, 2mg insufflated or 3-4mg oral hydromorphone ir.
In case one shot isn't enough, wait 2-3 hours and then apply 2 shots, but don't go any further. Although the half life and duration of action is short, it is context-sensitive (the more and longer it is applied, the longer the half life becomes) and therefore difficult to measure.
I've tried 4mg and 6mg Dilaudid IV in a hospital setting. The Narcan I have is also from a hospital environment and I have training to use it on patients. Understanding the difficulty of using on myself, however, I know it wouldn't be wise to rely on this as a primary safety measure. I'm hesitant about the use of Instanyl now, especially given the experiences I've heard that it has little/no recreational value or euphoria. I have some oxycodone pills lying around and maybe I'll give it a try when those are gone.
Doctor_Ew420
Bluelighter
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Yeah, definitely save the fent for when the good drugs are gone. I do like fentanyl, probably just because of its ridiculously quick action, I do get some euphoria from it, but nothing close to oxy or hydromorphone. Like people have been saying it is basically just a nod. A short lived one at that. I still like vaping the stuff though.
Narcan will work on fentanyl. However, it does not need to be administered IV- it can also be administered intramuscularly and even subcutaneously, which are both considerably easier in the context of an overdose. In a higher concentration (2mg/2mL), it can also be administered intranasally (as yet, not FDA approved, but is the current standard of care in many emergency medical settings plus in numerous OD prevention take home naloxone programs & IN devices are under development)
Anyone who wants a Narcan kit to prevent overdoses should search here for the closest program in the US and try here for programs in other countries.
prep a rig of narcan and have it next to you. intranasal is a somewhat slower roa (compared to iv) so you will have the time to self administer. I used an insulin pin loaded to about 50units of narcan, iv'd my shot and still usually had time to self administer narcan if it wasn't pure fent (street dope here is cut with it). so intranasal will provide some wiggle room for you. when you get that light headed, feel like I'm gonna pass out feeling (which is what I would get), inject into your quad as it is a large muscle. don't worry about apirating as if it enters a small vein you'll be fine. subcut. shots work as well. this was MY experience with self administered narcan. narcan can be used to bring yourself down if you get uncomfortable as well. smaller injections to bring down the high if needed (or to avoid withdrawal if dependent, use small injections but more frequent)