Opioids Increasing the BA of snorted Opana?

[curioushat]

How can I go about making sniffed Opana hit harder? It seems like I get really weak effects whenever I try to snort it. I've snorted 45mg on multiple occasions and gotten near nothing. I know the BA is higher for IV, but I don't want to resort to that. Is there anything I can do to make snorting more appealing?

 

[Tommyboy]

Am I correct in assuming you have either the instant release version of the pill or the older version of the extended release pills? If you have the newer version of the pills (the round ones) and somehow managed to break them down to sniff then it's still not going to work.

When snorting anything it's best to do small lines at a time, and sniff just hard enough for the powder to get into your nasal cavity. Allow a few minutes in between each little line. This allows it to absorb, allow for the fillers/binders to get out of the way, then allow for the good stuff to be absorbed when you do the next line. You can also try to eat 1-2 tagamet (cimetidine) pills or drink white grapefruit juice about 30 minutes before doing the Opana which will allow for more of the drug to build up in your system since it will take a little longer for your liver to break it down. Taking an antihistamine can cause more sedation so some people will take a little around the time they use the Opana to make the nod more pronounced.

If you aren't getting high anymore then take a break. It's the only answer that will allow you to have a somewhat manageable habit. If you keep doing more or switch to IVing then you will be chasing the high more and more, using more and more often, and even if you were to start IVing you would be shooting just as much as you were sniffing within a few weeks.

 

[bayhead415]

What form of the pill are you using?

If it is the IR that is your problem there as there is just way to much damn filler in it and it is probably preventing the oxymorphone from hitting the nose and just going through and down the throat into the stomach. Eat a fatty meal before and during to increase the oral BA from 10% to 30% making it closer to the 40% of the nasal BA so that hopefully some hits the nose to bring on the faster effect while the stuff in the stomach prolongs the effect. I also know people attempt to filter out the filler either with a syringe wheel filter or else a back loaded syringe with cotton. Some people even go the extra length to figure out the right ratio of IR to water so they can do a big batch that they than put into a saline nasal spray bottle to be able to easily administer a controlled amount. I have yet to attempt this, but will be doing it soon.

If you are using the old octogon ER than use fractions to break it into parts that contain 1-2.5 mg per line and do one line up each nostril. This has been the most effective way for me. If you are somehow breaking down the new smartie/skittle opana don't continue this as you will mess up your nose.

Grapfruit juice is also supposed to potentate opiates if I am not mistaken.

Anyways good luck with everything!

Edit: Basically going to clear up what he is saying with needle use... Do not get into it... It is a bad habit to start and a hard one to break as well as extremely dangerous unless in a sterile controlled medical environment with medical professionals that are not yourself even if you are qualified. You don't wanna end up nodding out before you can get the needle out of your arm... That would just suck although I doubt that is likely to happen, but still you never know.

 

[curioushat]

Ok thank you for the advice. Unfortunately a break won't help because this is my natural tolerance. I am once every two weeks or so, and it's been like this forever.
One thing I've always noticed is that I never get potent effects from snorting things. I think part of it could be the fact I can't breathe very well through my nose, one nostril at a time at best, and I can very rarely take full quick, powerful breaths. I've never broken my nose (to my knowledge) but it sounds like I have a deviated septum. So I'm thinking that maybe the powder isn't going far enough into the nose to be absorbed?

I'll try the fatty meal advice. I'll just chug some olive oil which is 100% fat. Wouldn't alcohol also make the BA closer to 50%?

Hopefully I can get the BA up high enough that the dangers of IV outweigh the benefits.

 

[bayhead415]

Do not mix with alcohol. Not only can it possibly weaken the effect, but it is just a really unpredictable interaction.

Also try eating a grilled cheese or something.... Chugging olive oil can not be good for your health. Or else try a waffle with syrup.

 

[Mass08]

As far as the nostril thing goes....everyone mainly breathes through only one nostril at a time. Our bodies have a nasal cycle in which it switches back and forth between each nostril throughout the day, so I doubt there's something wrong with your nose. Just a random fact.

 

[FlippingTop]

plug it.

 

[bayhead415]

As far as the nostril thing goes....everyone mainly breathes through only one nostril at a time. Our bodies have a nasal cycle in which it switches back and forth between each nostril throughout the day, so I doubt there's something wrong with your nose. Just a random fact.

hmm very interesting...

Also as far as plugging goes it does work very well, but I highly doubt it is as effective as nasal administration.

 

[curioushat]

Yeah pretty much from the research, oral is 10%, rectal 20%, insufflated 40%, and IV 100%. I know you can increase oral up to about 30%, which is actually fantastic for me. But yet, there's something about the rush that is totally missing.
With regards to insufflated, I guess it could be normal. I have been told my nose looks like it had been broken several times, it's crooked and the nostrils are shaped differently. It's just mind-boggling that I could have so few effects from a relatively large amount of Opana. Is there really no way to increase the BA through snorting it?

I do have the IRs by the way, not sure if that is relevant.

 

[bayhead415]

Do you have Endo brand/generic IR or roxxane IR? The endo are closer to 200 mg per pill (for the 5 mg at least) leaving 195 mg of filler, which is not just going to block the oxymorphone, but also is horrid for your nose. The roxxanes are 95 mg per 5 mg pill, which is a more realistic amount to work with although it is still quite a bit of filler. Look into making a nasal spray solution out of multiple by dissolving them in water, filtering somehow such as back loading a cotton loaded oral syringe than taking the time to force it through as it will clog, and than using the resulting liquid as is or in a nasal syringe if you have measured the liquid to yeild a solution of 0.5-1 mg per 0.1 ml. I still have yet to have success with these results and just use my IR in case of emergency.

I also notice if it is not broken down to a powder and left in a slightly chunky consistency it will not work at all. The roxxane form somewhat works for me insufflated, but no where near as well as the octagon ER. I actually just broke one down and for the first time got it into a powder after perfecting my method. I use a ceramic plate and a sharp razerblade (they dull over time) and cut it into quarters than working on each quarter until it is just somewhat chunky. Than I press down on it with a flat surface (pill bottle top) by gently pushing down on it as I roll the cap around the edge until it breaks and than rub it back and forth over the pill sometimes lifting to make sure it is a complete powder and lightly work on it with the razor blade after. The roxxane are pressed more densely so be careful when cutting through it to make sure it does not send pieces flying. Like I said a SHARP razor blade is key or else it will be extremely difficult to cut the roxxane form. You can tell which one you have by checking if it is white (roxxane) or blue/pink (endo). Honestly I don't think the endos are worth putting up the nose as there is too much filler and it takes so much time doing it over time in small amounts that it just does not work and will not lead to a rush and I would recommend plugging 5 mg and eating 5-10 with a fatty meal and than working up slowly by 5 mg orally if it is not working.

Hope I was able to help. Definitely keep in mind the fillers and the damage you are doing putting it all up your nose as it is not worth doing especially if you are not getting any effect. If you have issues figuring out how to make a nasal spray solution I am willing to work with you to help you develop a tek for yourself, but only if you prove you have done the research and can not figure it out on your own as I do not want to help someone who is not willing to do the research them self. Really the tricky part is figuring out a good ratio of pills to water so that the filtered solution is not to diluted requiring reduction as that can become pretty difficult and time consuming at least in my opinion. Good luck with everything and I hope you are able to work things out for yourself!

Edit: Yea since I powdered it without leaving chunks I can notice a very noticeable difference from when I used to use it from taking about 2/4 of the powder up the nose with 1/4 in each nostril.

Edit 2: Also curious what is the dose of your IR? Also are these scripted to help you manage pain or just some that you are able to get your hands on?

 

[curioushat]

Thanks for the advice. I definitely have the Roxxane 10mgIRs. They're fairly small, so 10/85mg I do think is a good ratio. I usually use the two spoon method. At that point it looks as powdery as possible, but maybe it isn't? I guess I can try harder with the razor blade to get it to work. I'd be down for oral, but I'd also like to be able to get that rush whilst on the peak. Is it possible that the two spoon's method of powder isn't nearly good enough?

I'm not prescribed these, and honestly I am extremely frustrated with this. I don't never do opiates but it's once every two weeks at the most for me. Sniffing 30mg of Opana should send me flying through the walls but it does almost nothing.

 

[bayhead415]

I do not think roxxanne makes 15 mg IR.... You probably have the activa 15 mg generics with the moon on one side. Make sure you do not include ANY of the waxy outside stuff into it. I use tweezers to hold down the wax and gently scrape the powder off after cutting it off from the center majority of the powder although I use the octagon shape ones which are easy to cut into fractions so that there is only one flat section of the pill with the wax to cut off making it easy to get mainly the wax without the powder. Try either a nasal spray or dropping a few drops of water into it with a oral syringe or straw so the powder clings to the water. I have not had any experience with these, but I read they do work although they break down into such a fine powder it is easily to inhale it through the nose and into the lungs. Be VERY careful and inhale as lightly as you can with your head tilted so that as it exits the straw it will land on the inside area of the nasal cavity.

Also for the sake of harm reduction... Recreational opiate abuse is a VERY dangerous habit and I highly recommend not getting into it. I use due to a back injury... If I did not have it I would just use opium at the end tail of psychedelic journeys or maybe oxymorphone/oxycodone in a line. Trust me it is not worth it to allow your body to become dependent on these for the rush. Also do not get into needle use as even though it does provide the rush it is a VERY gangrenous and unhealthy habit especially with the formulation you have. I am being serious as it is no joke and I want you to really think about whether or not it is worth the damage to the body as well as the cost.

Edit: To go a bit further on my cutting method first I split it in half so I can stand it up. As it is standing I cut both the front and back large wax parts to leave only the sides. With the octagon I can than cut where the sides bend to leave flat chunks of wax that are easy to remove with the razor blade. With the circular shape it may be harder to do this, but you still probably can remove most of the center from the outer wax and than continue with gently removing the powder from the wax with tweezers. I than eat down the wax skin that I removed just in case any is still left on. I highly recommend tweezers as they help make clean cuts as well as hold the wax pieces down. I actually found that holding the half as it was standing with the tweezers aloud me to make a cleaner flat cut on the larger wax surface.

Edit 2: Also start small.... When I did not have a tolerance I could barely insufflate 2.5-5 mg without getting close to nausea.

 

[curioushat]

I feel like an idiot, they were 10MG IR, but still that doesn't change the "barely any effects" part. I didn't look up the number so maybe I got beat and it was codeine or something... Otherwise, I don't know.

 

[bayhead415]

Ya it still does have quite a bit of filler per pill.... Honestly the only good ones for nodding are the old octogon ER. You can snort the roxxanne IR and IMO it works, but it does not get close to a nod. As I have mentioned I only use it in case of emergency when I am out. I will be trying to make a nasal spray with my next script so I will update this if I try it out.

Edit: \/True dat.... Hell I would not be surprised if a dealer tried to pass a laxative off as a drug... Although I doubt that happens very often\/

 

[Tommyboy]

I feel like an idiot, they were 10MG IR, but still that doesn't change the "barely any effects" part. I didn't look up the number so maybe I got beat and it was codeine or something... Otherwise, I don't know.

Always look up the pill markings to confirm what you are taking before consuming it. You can't just take a dealers word for it.