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  • BDD Moderators: Keif’ Richards

Immunity to drugs?

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forshan

Greenlighter
Joined
Jun 23, 2011
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8
After getting to the point where i get sick from even a sip of beer, i decided to start trying out various drugs, but none of them seem to have any effect on me.

ive smoked weed a dozen times, nothing, and much more at a time than my friends do
ive taken 2 2.5/325 percocets with no prior opiate usage, and nothing
took 2 T4s, nothing
took 4 lortab, nothing

what should i do?
 
All of those are very very small amounts of drugs. Some people lack the enzyme that gets you high off codeine, so that could be your case. did you take it on a stomach that had been emoty for at least 5 hours? If not you're pretty much wasting your drugs. It's also a good idea to chew your pills to aid with absorption.

I would try 3-4 tylenol 4's (180-240 mg codeine) on an empty stomach with quercetin supplements and a 50-100 mg diphenhydramine. Search for opiate potentiation for some more tips. If the codeine doesn't work then you lack the enzyme so I would try 30-40mg hydro or oxy and the same thing. Make sure you take all your opiates at once because they often inhibit the enzyme that breaks them into psychoactive active compounds

If all fails you could try railing them, but I doubt it won't work
 
i knew the perc and t4's werent going to do much, but i thought 20mg of hydro would at least have an affect when ive seen my mom go loopy on half a perc

i took 2 at first then chewed the other 2 like 15 min later, would that have been what did it?

and idk when im gonna have any again
 
Some people can smoke weed a couple dozen times without it effecting them. It's weird, but sometimes it takes a certain amount of attempts before you start feeling the high. The other doses are somewhat small, but not for someone without an opiate tolerance. Next time you have anything you are wanting to try, I would research a bit first. Hydrocodone (lortab) is a drug where redosing doesn't have much effect, but only spacing the doses 15 minutes apart, I'm not sure that played much of a factor.
 
im going broke, and getting nothing done, ahaa
i had researched the t4 and lortab, and i knew the t4 prolly wasnt going to do anything, but i read about people saying 10mg hydro was enough your first time
 
I've found that waiting over 5 minutes to redose kills the high. Did you do this on a stomach that was empty for at least 5 hours? Are you on any other medication? I'm wondering if the codeine inhibited the enzyme THEN you took the lortab? Also are you sure these pills aren't bunk and are the doses you say they are? pills come in many doses

Otherwise idk what to tell you. Opiates aren't meant to be abused by everyone
 
i dosed at like 11, ate around 6ish
the codeine was last night
i stole them from the pharmacy i work at, theyre the real deal
 
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Hmmm, I would wager what happened is you lack the enzyme (can't remember what it's called) and didn't take enough oxy do to anything, so when you redosed the enzyme was already inhibited and couldn't turn the hydro into an active product. I would try again without the codeine and in a much higher dose. Did you take anything with the drugs? I'm surprised you didn't get incredibly itchy with all the histamines released.

Sometimes you need to know how to enjoy the drug- did you run around or did you try very hard to relax and nod? It's easy to miss the buzz if you don't know what to look for. And you aren't on or have been taking any medications?

i find that most people can only get high a certain amount of times off of a certain class of drug (despite not having a tolerance) so they have to move up the chain and take something more euphoric. Maybe you smoked too much weed back in the day!
 
I've found that waiting over 5 minutes to redose kills the high. Did you do this on a stomach that was empty for at least 5 hours? Are you on any other medication? I'm wondering if the codeine inhibited the enzyme THEN you took the lortab? Also are you sure these pills aren't bunk and are the doses you say they are? pills come in many doses

Otherwise idk what to tell you. Opiates aren't meant to be abused by everyone



The empty stomach thing is b.s., me & my friends eat big meal & what not & then dose after an hour & we get high as much as anyone else that didnt eat.
 
im not trying to be a dick, but get off your high horse. first of all, you probably are not inhaling right when you smoke weed or are smoking oregano. secondly, opiates took a couple of times to hit the sweet spot for me. there was no way that i took the hydrocodone wrong as i swallowed it, but i just wasnt used to the effects of opiates so i didnt know what to expect. after a couple of trys, i got really really really high like noddin off and shit
 
The empty stomach thing is b.s., me & my friends eat big meal & what not & then dose after an hour & we get high as much as anyone else that didnt eat.

If that's the case you are very lucky freaks of nature. A large portion of oral drug absorption occurs through the stomach lining. If you have a full stomach the pills will be competing with the food. It will take longer to kick in and will release over a longer period of time. I find if I take 50% higher dose on a full stomach, I get just as high (after a bit longer wait for it to kick in) and it lasts longer which is nice, but again, I have to take more drug.

Oral drugs absolutely do kick in faster, and harder on an empty stomach. If you are snorting or shooting, then it doesn't make much difference what you eat. But if you are using an oral ROA, then it does. Why do you think there are so many prescriptions that say "take with food" or "take on empty stomach"?
 
This topic would be more appropriate for Basic Drug Discussion. Drug Culture is for discussing the social nature of drugs, and topics related to that.

DC-->BDD

To address the OP's question, it looks like you're taking very small amounts of each of these opioids. In addition, many people simply do not get good, recreational effects from opioids (and sometimes side effects like nausea or urinary retention.)

What is your weight? Were all these medications taking before/during/after eating? All of these factors can influence how strongly you feel the medication. I seriously doubt you're immune, there are just other factors you aren't taking into account here.
 
Next time you are planning on taking a pharmaceutical recreationally, you should search the imprint of the pill online to make sure its legit. I know people that say they dont get high off of hydrocodone, and later found out that they got ripped off and the pills were infact not hydrocodone. You could just be taking Tylenol or vitamins for instance.
 
I'm 6' 210
It was around 11pm. I last ate around 630
I know the t4 and perc were low. But I thought 20mg of hydro would do something when I read about others getting high off 5 or 10
And they were all legit the hydro was m357
 
My other half has a natural high tolerance to drugs. Fuck knows where it came from but you're not alone. Trust me.

I on the other hand have a natural low tol. both can be a bit disturbing but in different respects.
 
My other half has a natural high tolerance to drugs. Fuck knows where it came from but you're not alone. Trust me.

I on the other hand have a natural low tol. both can be a bit disturbing but in different respects.



Im in the same spot. I have a low tolerance & my gf that is like 115 pounds has a high natural tolerance. If I took the stuff she can handle, I would be in the ER.
 
After getting to the point where i get sick from even a sip of beer, i decided to start trying out various drugs, but none of them seem to have any effect on me.

ive smoked weed a dozen times, nothing, and much more at a time than my friends do
ive taken 2 2.5/325 percocets with no prior opiate usage, and nothing
took 2 T4s, nothing
took 4 lortab, nothing

what should i do?

What "high," exactly, are you expecting? If you're expecting to take a couple percocets and feel like a cartoon character, then that's just not going to happen, not for you and not for me.

The first couple of times that I experimented with oxycodone (percocet / oxycontin), I wasn't sure what to expect. I hadn't yet learned to associate the sometimes subtle effects with the substance I had taken, oxycodone. I was anxious to feel something more than just a warm sensation in my face, sedation, the general sense of well-being and relaxation.

This could be what's happening in your case. I don't know.
 
I've heard people get flushed. Tired and have a sense of well-being
Nothing of the sort. I got 4 perc 5/325 should I take all 4?
 
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