Staying in this nifty looking little retreat about an hour from Iquitos. Will be doing the retreat for a total of 10 days, but will be in Peru for a total of six weeks.
Words can't really express my excitement. As a 28 year, college educated, white male, I have definitely done my share of using/ dosing..... never with anything like ayahuasca though. The most I've done is mushroom munching. If everything I've seen/ read on the aya comes to fruition I'm in for one hell of a ride.
Any of you here have any experience with Ayahuasca? If you've never heard about it, check it out. A life altering 'medicine' from the Amazon rainforest.
Here's a little copy/ pasta for you about Ayahuasca:
"The primary active compounds in B. caapi are the alkaloids harmine, harmaline and tetrahydroharmine. They all belong to the β-carbolines group, which implies they are MAO-inhibitors. The primary active compound in P. viridis and D. cabrerana leaves is the indole ethylamine alkaloid n,n-dimethyltryptamine. Tests of different samples of Amazonian brews have found 25 to 36 mg of N,N-DMT per dose. It has a similar structure to serotonine and thus has affinity for several serotonergic 5-HT2 receptors. DMT is, like LSD, a partial-agonist on the receptor subtype 5-HT2A. When humans take DMT by itself orally, it is converted into inactive aldehydes by the endogenous enzyme monoamine oxidase.
The β-carbolines in the vine temporarily inhibit the production of this enzyme, allowing the DMT to reach the sensitive parts while still active. Inside the nervous system these are located near most of the serotoninergic terminal rich areas, including the neocortex (mainly the prefrontal, parietal, and somatosensory cortex) and the olfactory tubercle. Outside the nervous system 5-HT2A receptors are present in platelets (cell fragments, circulating in the blood, that are involved with clotting) and some muscles."
Words can't really express my excitement. As a 28 year, college educated, white male, I have definitely done my share of using/ dosing..... never with anything like ayahuasca though. The most I've done is mushroom munching. If everything I've seen/ read on the aya comes to fruition I'm in for one hell of a ride.
Any of you here have any experience with Ayahuasca? If you've never heard about it, check it out. A life altering 'medicine' from the Amazon rainforest.
Here's a little copy/ pasta for you about Ayahuasca:
"The primary active compounds in B. caapi are the alkaloids harmine, harmaline and tetrahydroharmine. They all belong to the β-carbolines group, which implies they are MAO-inhibitors. The primary active compound in P. viridis and D. cabrerana leaves is the indole ethylamine alkaloid n,n-dimethyltryptamine. Tests of different samples of Amazonian brews have found 25 to 36 mg of N,N-DMT per dose. It has a similar structure to serotonine and thus has affinity for several serotonergic 5-HT2 receptors. DMT is, like LSD, a partial-agonist on the receptor subtype 5-HT2A. When humans take DMT by itself orally, it is converted into inactive aldehydes by the endogenous enzyme monoamine oxidase.
The β-carbolines in the vine temporarily inhibit the production of this enzyme, allowing the DMT to reach the sensitive parts while still active. Inside the nervous system these are located near most of the serotoninergic terminal rich areas, including the neocortex (mainly the prefrontal, parietal, and somatosensory cortex) and the olfactory tubercle. Outside the nervous system 5-HT2A receptors are present in platelets (cell fragments, circulating in the blood, that are involved with clotting) and some muscles."
