I just took MDMA the other day, two hours before that I took my prescription tramadol, 100mg, and earlier that day I took 100mg as well, i noticed to bad interactions. They say it's dangerous but I'm assuming you need to take crazy stupid amounts of both, "I'm assuming". Stay calm is all you can do, perhaps vitamin c can help kill the roll as acidic foods decrease absorption of aamphetamines....benzos or lyrica or neurontin may help to decrease odds of seizure due to tramadol.