So someone who knows what they're talking about actually posts something intelligent in this forum and the response is "dood shut up i just wanna roll bawlz"? For me, BL is all about learning, hostility to intelligent discussion is really pretty stultifying and dissuades posters from coming in this forum to post.
I understand your frustration Vader I bet that post took you ages to write. I for one definitely value your input and everyone else does also. I guess as that is one of the most complex posts to date sometimes its easier to not respond just incase as a novice we fuck it up.
Please dont despair or get upset I will give it a go
Having someone that does know the fuck about what their on about really does help.
I think a mixture of "Science Chat" and " These Pilz Rock" makes this thread a lot of fun. Everyone can rock in on what ever level they like.
It is N-Dealkylation that appears to perform the task of MDMA > MDA
Well yeah, MDMA is MDA with an N-alkyl group, so naturally that transformation is an N-dealkylation.
I guess why I was pointing this out is because when looking at this process from a clandestine perspective it seems no one usually bothers. I think this is because MDA is already an active product also this conversion process seems to produce low yields. Would the body also produce a low yield? What happens to the waste from these body reactions? How the fuck can we do this without combined heater stirrers, condensors etc.
Amphetamine is a complex clip of alpha-methylphenethylamine, the amphetamines are just the phenethylamines that have a methyl group at the alpha position.
Wiki definitions
Methyl group - Methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms —CH3
Alpha position - The alpha carbon in organic chemistry refers to the first carbon that attaches to a functional group
So looking at your diagram referring to the 'hexagon shit' in laymens talk 'amphetamine' its a squiggley line coming off an aromatic ring at 2oclock. And to define an amphetamine one of these squiggley lines must have nothing at the end of it indicating 3 Hydrogen atoms?
Is therefore shapes 2,3,and 4 amphetamines? fuck knows what 1 is?
Its the stick thats not attached to anything. The end of the stick 'referring to bond line drawing' is the one carbon atom by default having three hydrogen atoms because its not connected.
The fourth amphetamine has two 'lone sticks' one connected alone to the aromatic ring. Would I be write in saying this has two Methyl groups? also has two alpha positions?
In chemistry, it is much more important that each name refers to a unique chemical than that each chemical has a unique name.
Is this like the way you have highlighted this alpha-methylphenethylamine it has five descriptions in it. Ie five different descriptions of what it is.
3,4-methylenedioxy-N-methylamphetamine means exactly the same thing as N-Methyl-3,4-methylenedioxy-A (where the A stands for amphetamine), the order the substituents are named in doesn't matter. You could call it other things, like 3,4-methylenedioxy-N,a-dimethylphenethylamine, it's confusing if you're not au fait with it but persevere and it will come naturally.
You could break MDMA up to be (3) (4) (Methylenedioxy) (N) (Methyl) (Amphetamine) and shuffle the words round however you desire?
In this formation 3,4-methylenedioxy-N,a-dimethylphenethylamine. I assume a-dimethylphenethylamine means Methyl Amphetamine.
Hopefully I understand it. Its a language thats for sure..
The numbers refer to the positions of the substituents on the ring, relative to the ethylamine chain, which takes priority and so is numbered 1. So, the position next to the ethylamine chain is 2 (or 6), the position two carbon atoms away from the ethylamine chain is 3 (or 5), and the position opposite the chain is the 4 position.
Substituent - substituent is an atom or group of atoms substituted in place of a hydrogen atom on the parent chain of a hydrocarbon.
Ethylamine Chain - Ethylamine is an organic compound with the formula CH3CH2NH2. The chain is the line that comes off the ring.
just out of interest does this have no ethylamine? because theres no CH3?
http://en.wikipedia.org/wiki/2C-B-FLY
Where I am confused is MDMA doesnt have CH3CH2NH2 it has CH3CH2NH? Why is this?
So in layman terms 3,4 in relation to MDMA means where another group of atoms is attached to the primary aromatic ring.
Is this so you are able to draw the line diagram using just the chemical name?? You have all the jigsaw pieces from the name but the numbers give you the position of where to draw? by convention you use where the ethlamine chain connects as position 1 and count anti clockwise from there.
So, in the image I posted, the bottom structure is mephedrone, 4-methylmethcathinone, and the methyl group is opposite the other substituent on the aromatic ring.
Methyl group - Methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms —CH3
hasnt this molecule got three methyl groups? I see three ends all having three hydrogens?
In MDMA, the methylenedioxy group bridges two adjacent carbon atoms, 3 and 4, or the position opposite the chain and the one next to it. So, 2,3-MDMA is what is called a structural isomer of 3,4-MDMA, with the structure differing only in the placement of functional groups. In this molecule, the methylenedioxy bridge is on the carbons 2 and 3. This is getting confusing, so I'll post an image (3,4-MDMA is the first structure, 2,3-MDMA the second):
So it seems you can count either clockwise or anticlockwise from position 1?
Just so you understand what I am saying assume counting anticlockwise. if 2,3 mdma is an isomer then i assume 5,6 is the other isomer?
Switching back to how you count either clockwise or anticlockwise is the isomer position 2,3 then indicated by 2,3+ or 2,3- instead of 2,3 and 5,6?
Now, you might be thinking that you could make 4,5-MDMA, the bottom structure, and have another new drug. This chemical is in fact the same as 3,4-MDMA, the benzene ring can be rotated 180 degrees about the ethylamine chain (this is possible, carbon atoms that share a single bond can rotate relative to one another) and the two structures are seen to be equivalent. Hope this helps.
Now I actually think about this I get confused???
If 3,4 and 4,5 are the same. Is this Racemic MDMA?
this means 2,3 and 5,6 are the same. if so why the + and -
Are there theoretically four types of + or - charged mdma?
So when Severely said this:
@ Folley - Racemic mixture of MDMA as we know it contains d-3,4-MDMA and l-3,4-MDMA. But those are only the enantiomers of 3,4-MDMA.
d-3,4-MDMA and l-3,4-MDMA means (counting anticlockwise 3,4 and 4,5) (assuming the d and l refers to the position so you can use just 3,4)
Enantiomer meaning non-superposable (not identical). I thought you said it was ideantical??
What about 2,3-MDMA? Has GC/MS ever found 2,3-MDMA in a sample? I am curious...
I assume to be totally correct this should say "What about + 2,3-MDMA or -2,3-MDMA? Meaning has an MDMA isomer ever been detected on GC/MS?
The S+R and the D+L also gets confusing as well. I assume this must be some other form of chemistry language.
I hope you dont mind the questions.
A lot of the confusion seems mainly based around a TRANSLATION process.
Very interesting all the 'Hexagon Shit' means a bit more now LOL.