MisterHijack: Do you have any medical conditions that make this a concern for you? It's been around 15 years since I've taken HBWS, but I never remember having any issues with this aspect. The nausea on the other hand, did eventually turn me off, but I do have underlying stomach issues and ulcers at the time.
I found 8 seeds seemed to be roughly equivalent to 100 micrograms of LSD, give or take. 16-24 seeds produced pretty profound experiences, although the nausea at that point pretty much put me out of action for the whole trip. I found the experience closer to mushrooms than LSD, though - a little different than either, but definitely more euphoric than LSD; a preferable drug IMO if it weren't for the nausea.