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How quick does tolerance build up exponentially? (e.g. on top of existing tolerance)

Jesusgreen

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May 6, 2010
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Alright, basically, for some reason since I got this 2C-E I've found it quite hard to remain sober, I've always had that with drugs, figured psys would be different since I didn't have that problem with 4-AcO-DMT really.

Basically, I first dosed last Wednesday, then Friday, then Saturday, then Sunday, then again this Wednesday, all at night except Sunday where I dosed at like 4pm or something.

Now what I'm wondering is, how much will my tolerance have increased? The first trip I obviously had 0 tolerance - my first time using 2C-E, the second trip I didn't really notice tolerance - it was far more intense than the first and I dosed a similar amount, the third trip was weak but still enjoyable - I convinced myself I'd take a week or two break before my next trip, however the next day I was given some legal bud containing JWH-073 and since I hadn't toked up in 4 months, decided I'd trip and smoke (wasn't enough to save some for later) - did that, had a very intense time, mostly due to the JWH. Then 3 days later on Wednesday night I tripped again, with a fairly large nasal dose - and the trip was very weak, mild OEVs and the CEVs were barely any more intense than CEVs I get when sober, plus there was no headfuck - which, while I hear is a common occurrence with 2C-E, doesn't match up with my previous trips, as they had a very strong head high - just not as confusing as 4-AcO-DMT.

Anyway, time-line wise:
Wed Thu Fri Sat Sun Mon Tue Wed Thu Fri Sat
Trip No Trip Trip Trip No No Trip No No No

Is my tolerance likely to be lower or higher than on Wednesday today? On the one hand, I'd assume it'd be lower because the majority of my trips were ~1 week ago and so should not be affecting my tolerance very much now - on the other hand, I know tolerance with a lot of drugs builds up and increases exponentially - so is my tolerance actually even bigger now?

Also, final question - when is my tolerance likely to be baseline/relatively low? I found 4-6 days after a trip was more than enough with 4-AcO-DMT, but then I never dosed so many times in a short period of time with that.

Thanks in advance. Apologies if my post is a bit long or I don't get my point across until the end, barely slept the past couple days and haven't eaten either, so my head's a bit of a mess - going to go finally eat something now while I wait for replies.
 
Yeah, you should be fine in a week or so.

I know 2C-E, along with 2C-I and 2C-C, has been found to both mildly inhibit the reuptake of monoamines and mildly release them, while most tryptamines I've seen figures for mildly inhibit the reuptake of serotonin only (the HUGE exception being aMT, which behaves more like MDMA). People say 2C-E is neutral emotionally, but I've always found it to have a strong positive push, which is consistent with the data. I've used small IM doses with amphetamine for blissful recreational experiences in the past (though it's really easy to get into strong psychedelia if you're not careful), and I can definitely see how these kinds of euphoric noncommittal ways of using it would reinforce compulsive use a lot more than with most tryptamines.
 
Yeah, you should be fine in a week or so.

I know 2C-E, along with 2C-I and 2C-C, has been found to both mildly inhibit the reuptake of monoamines and mildly release them, while most tryptamines I've seen figures for mildly inhibit the reuptake of serotonin only (the HUGE exception being aMT, which behaves more like MDMA). People say 2C-E is neutral emotionally, but I've always found it to have a strong positive push, which is consistent with the data. I've used small IM doses with amphetamine for blissful recreational experiences in the past (though it's really easy to get into strong psychedelia if you're not careful), and I can definitely see how these kinds of euphoric noncommittal ways of using it would reinforce compulsive use a lot more than with most tryptamines.

Yeah that's the problem for me I think. With 4-AcO-DMT, the push is there, but it is somewhat lacking at lower doses - at higher doses it is overwhelmingly euphoric - however to achieve this kind of intensity you either need low/no tolerance or a very high dose - with 2C-E it seems like low doses/dosing with high tolerance = stimulation and intense euphoria, along with mild visuals/trippyness, making it quite a compulsive substance - plus, since at these lower doses it feels like "something is missing" - even knowing that my tolerance is already high, it's easy for me to redose in the hope of having a more complete trip.

My plan is to wait until next Wednesday when it'll have been a week since I last tripped - see if I feel like tripping, and if not, trip next Friday or Saturday.
 
I (ab)used 2CE and 2CI multiple times a week for at least a month. I found that the headspace quickly lost its 'magic' and became much more amphetamine-like, making me talk/type a mile a minute with somewhat altered thoughts but nothing all that 'psychedelic'. The visuals and stimulant effects, on the other hand, stayed much more consistent. After a few nights of binging I could take 30+ mg oral doses, have many hours of rich visual activity, be wired as hell all night, but be able to hold a more or less normal conversation, seeming no more out of my own skull to the other party than I would if I had popped some adderall.

I notice the tolerance effect mostly when I take a break and then trip again. Over repeat doses it builds up subtly enough that I hardly notice and I don't rapidly increase my dose to compensate like people do with cocaine, opiates, etc. (I've done enough 2CE to have a pretty good idea of what a "20mg trip" feels like, or a "25mg trip", etc., so I just take the amount I'd normally want with at most a 5mg boost to compensate for tolerance)
 
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