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Opioids how much codeines is it safe to do in 1 day

tunesey

Bluelighter
Joined
Jan 26, 2013
Messages
563
I went to my doctors in agonising pain this morning and the tight git only gave me 30/500 co-codomol I did a a CWE with 10 tabs 300mg 9 hours ago when will it safe to do another. My other doc gives me dyhadrcodeine for my pain but he was not on duty any advice quickly would be good cos I am suffering.
 
If I'm.not mistaken, you can do as much as you can handle........I've read the ceiling dose is 800mg for codeine tho.
 
Yea I think 1000 is the ceiling point but I don't reccomed you do that much you won't be taking a shit for weeks which in itself will be very painful.
 
Thanks guys I usually only do I a day and first strain through some old denim jeans then coffee filters. I needed it quicker this tome so did the coffee filters first then the denim it came out much cloudier but I reckon it was safe to drink it also tasted much more bitter than usual. I guss more fillers got through as I always double up on the coffee filters. Well heres to a pain free evening hopefully cheers guys.
 
Your welcome hope you stay pain free and don't have to keep taking a whole bunch of that crap.
 
Official guidelines state 420mg in any 24 hours period.

Though as it's a pro-morphine drug and an equipotent allowance of morphine is significantly higher than 420mg, I don't see why you can't consume ~1,000mg.

After 420mg I think the issue is more of one's ability to metabolise the larger doses of codeine.
 
As stated in the above post, you can do more.. but it would be a waste to do so.

Once you reach the threshold you'll start getting limited returns on how well the drug works. It's best to do your dose all at once once every 24 hours or so.
 
Well they're would be a ceiling on morphine conversion, however this would be highly variable among people, and as no studies whatsoever have attempted to find it, we have only anecdotal evidence to go on.

Codeine is metabolized to morphine rapidly, so they're should be no problem taking hundreds of mg's, for most people, though.

Lets not forget, C3G, another metabolite of codeine, is also an active opioid, and therefore contributes (some) analgesia as well.

Fun fact: Howard Hughes spent the last several years of his life injecting codeine into his muscles, several times a day, every day!
 
Well they're would be a ceiling on morphine conversion, however this would be highly variable among people, and as no studies whatsoever have attempted to find it, we have only anecdotal evidence to go on.

Codeine is metabolized to morphine rapidly, so they're should be no problem taking hundreds of mg's, for most people, though.

Lets not forget, C3G, another metabolite of codeine, is also an active opioid, and therefore contributes (some) analgesia as well.

Fun fact: Howard Hughes spent the last several years of his life injecting codeine into his muscles, several times a day, every day!


You would think Howard had enough money to get the really good pain meds instead of shooting codeine, goodness sakes.
 
I know, right! And he was Apperantly in near-constant pain! Strange.

But he was using it so much, at his autopsy, he had needles broken into his arm muscles...
 
I suspect Howard was an ultra-rapid metabolizer, which would (at least partially) explain why he stuck with codeine. If he really was an ultra-rapid CYP2D6 met., then he could conceivably get a 25% yield of morphine, so he injects 300-400 a pop, and gets a good dose of morphine!

Nothing would surprise me, that was a strange dude, but, yeah, I respect his work.
 
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