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How long does psilocybin...

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About 6 hours for main effects. The chemical might linger for a bit but I'm not sure.

Mixing with ecstasy is a great combo. Mushrooms and MDMA combo thread
Amphetamines might be a bad mix; recipe for paranoia/anxiety attack IMO.
Tylenol wouldn't have any interation. Not sure about Lunesta; I don't know much about it except it's a sleeping pill.
 
About 6 hours for main effects. The chemical might linger for a bit but I'm not sure.

Mixing with ecstasy is a great combo. Mushrooms and MDMA combo thread
Amphetamines might be a bad mix; recipe for paranoia/anxiety attack IMO.
Tylenol wouldn't have any interation. Not sure about Lunesta; I don't know much about it except it's a sleeping pill.

Thanks :]]

I do a lot of Ecstasy, but I'm not ready for a hippie flip yet,

not untill I've tried some shrooming solo first.
 
ive always found amphetamine mixed with mushrooms to be a great combo. keeps me from getting totally confused.
 
stay in one's system?

Does it mix bad with Ecstasy?
Mix bad with Amps?
Mix bad with Tylonel, or Lunesta?

It is kinda intense with amphetamines. I took like 60 mg vayvanse and 100 mg Provigil as well before taking about 3.0g of cubensis. It was fucking intense. I find the amphetamines mixed with shrooms make my stomache ache a little whereas psilocybn on its own don't!
 
For medication interaction visit the appropriate subthread of the Big & Dandy Mushroom Thread.

Other questions have been answered and about psilocybin staying in your system:

http://www.erowid.org/plants/mushrooms/mushrooms_testing.shtml said:
Once ingested, most of the psilocybin is converted into psilocin within the first hour. Most of the psilocin is then excreted within the first 8 hours...but portions remain in the system for several weeks. From Stafford's Psychedelics Encyclopedia

"High dose studies of rats suggest that psilocin taken orally is distributed throughout the body. Concentrations in tissues appear highest about half an hour after ingestion, decreasing rapidly over the next three to four hours. The adrenal glands of the test animals show the highest concentrations after the first hour, until then the kidneys have more. The small intestine, skin, bone marrow, lungs, stomach, and salivary glands also have significant concentrations-- greater, in fact, than those in the brain...

In the high dose study of rats, all but 6 percent of the psilocybin was excreted within twenty-four hours. In humans, only 80-85% of psilocybin and its metabolites are excreted within 8 hours, in the urine (about 65% ), bile and feces (15-20% ). Some 15-20% lingers on, stored in fatty tissues; significant quantities appear in urine up to a week later. A full 25% of the originally administered dose enters urine as psilocin."

source: http://www.erowid.org/plants/mushrooms/mushrooms_testing.shtml
 
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