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How high are you? v. Summertime: livin is easy

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DXM, and other dissociatives too, can potentiate opiates quite well. I don't think bupe has any sert-activity whatsoever, so it's safe with DXM. I'm rather sure of that.

Thanks, that makes me feel way better. My high is starting to wear off a bit now. I think I'm going to take my other 2mg of bupe for the day with DXM. How many mg DXM will I need (I heard about 20-60mg will do the job don't wanna take enough to try to trip again cause I don't think that'll happen)? Also how long before or after I take the bupe should I take the DXM?
 
Thanks, that makes me feel way better. My high is starting to wear off a bit now. I think I'm going to take my other 2mg of bupe for the day with DXM. How many mg DXM will I need (I heard about 20-60mg will do the job don't wanna take enough to try to trip again cause I don't think that'll happen)? Also how long before or after I take the bupe should I take the DXM?

I would start with the DXM and trip on that and then plan the intake of your bupe so it coincides with the time when the effects of the DXM starts to disappear.

Then you will get a DXM trip followed by bupe euphoria.

In my opinion you should not take DXM and bupe at the same time. The DXM trip will be happening just as the highest amount of bupe euphoria takes place if you take them at the same time. That will be a waste. Get the most out of the DXM trip and then get the best euphoria possible from the bupe just when the biggest effects from the DXM starts to wear of.
 
Thanks Ignio. You're right taking them at the same time last night was a waste. I think I'll do 200-300mg DXM tonight (and hold off on doing it again for about a month so I don't build my tolerance up much) then I'll take the bupe in the morning as soon as I wake up and be really high all day :)
 
Thanks Ignio. You're right taking them at the same time last night was a waste. I think I'll do 200-300mg DXM tonight (and hold off on doing it again for about a month so I don't build my tolerance up much) then I'll take the bupe in the morning as soon as I wake up and be really high all day :)

The perfect plan ;) Just like I would do it :P
 
4 's 30mg damphetamine, 20 mg Valium. and a minimum of 5 cigerette size joints( lost track and taking on 5 minute break over 7 hours. Best hits came from using toilet paper roll for power hit, but just casually smoking.
 
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D-amphetamine is a great prescription ADD/ drug with mainly mental stimulation, with enough physical energy to help you get moving. Of course your mileage with this medication may vary.
 
Took the 320mg DXM about 5-10mins now I wait. I was going to try and make it until morning before I took any bupe but the pain wasn't tolerable so I caved and took .5mg.
 
I agree that it is the fact that Etizolam is a triazolobenzodiazepine or thiendiazepine that gives it other qualities than normal benzodiazepines.

Etizolam
4-(2-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
512px-Etizolam.svg.png


The upper phenyl ring is replaced by thiophene compared to for instance diazepam, alprazolam and oxazepam. This adds potency and the thieno and triazolo adds the special effects people experience from Etizolam compared to other benzo's.

Regarding brotizolam, there's an even stronger version;
Flubrotizolam
2-bromo-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepine
Flubrotizolam is probably one the most potent and hypnotic RC benzo's that can be made right now. In years people have been speaking about the possibility of making it, and now vendors in China and Indonesia have it listed for sale. So we might see it on European and American RC sites if it is for real. In some way I hope we do, because I wanna try it :D But I think it will be so potent and hypnotic that we will see an enormous amount of people experiencing black outs as they cannot handle the potency which will make policy makers focus on the RC market again. It might be so potent that we have never seen anything like it. But currently, it is available on Asian sites, whether it is actually Flubrotizolam that they have made succesfully is another question though.

It is closely related to
Flubromazolam
8-bromo-6-(2-fluorophenyl)-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

You can see how Flubrotizolam both have the thieno and triazolo ring like Etizolam does. So I think it is the combination of the two that makes the greatest change from normal benzo's.

Normally you say that benzo's with a nitro ring is the most recreational, like:
Clonazepam
1,3-dihydro-7-Nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one
Clonazolam
6-(2-chlorophenyl)-1-methyl-8-nitro-4H-s-triazolo- (4,3-a)-(1,4)-benzodiazepine.

But for me the combination thieno and triazolo rings seems to be the most euphoric benzodizepines. But it is so subjective which benzo's people like the most and how they influence people are also very different. Etizolam is by far my favorite benzo and on a shared second place we have clonazepam and clonazolam, but they are in no way in the same league as Etizolam. I really mean it when I say that sometimes I experience so much euphoria from Etizolam that I like it better than opiats, and I cannot live with opiats, so it really says a lot. I wish I could find out why it is only sometimes that I experience this euphoria.


Back to the topic.

It is one hour past midnight here, I have been dipping into the cocaine I have purified, so I have had an absolutely wonderful evening. Now I am starting to mix ketamine into the lines so I will experience a K-hole and fall a sleep after that. Last time I experienced a K-hole it was like I was in a world like HBO's series Westworld, it was so strange ;)

Brotizolam might have the potential for an even more potent big brother, but it fits the bill of what you say are your favorite 'benzos' are (thienos doesn't sound right, yaknow) - namely triazolo & thianodiazepines combined in the same substance, rightfully so & I agree they are the most recreational by far. Brotizolam is my favorite hands down Equipotent to triazolam. It's plenty potent IMO with 250mcg being quite strong and also IME by far the best (thienodiazepine) sleep medication on the market, it has the most euphoria and is the most potent of all the 'benzos' on the market in Belgium

(I actually prefer it over flunitrazepam). It's great and obtainable via a script. So real easy to get your favorite dose (obv) measured, no dissolving in pg & liquid measuring of doses required. Hmm, reminiscing about this epic med is kinda making me feel like I might actually go ahead and try obtaining a box of these sometime soon. I might even try getting brotizolam added to my daily 'diet' when I go see my GP today (or tomorrow at the latest). I'm srsly considering it.
 
Brotizolam might have the potential for an even more potent big brother, but it fits the bill of what you say are your favorite 'benzos' are (thienos doesn't sound right, yaknow) - namely triazolo & thianodiazepines combined in the same substance, rightfully so & I agree they are the most recreational by far. Brotizolam is my favorite hands down Equipotent to triazolam. It's plenty potent IMO with 250mcg being quite strong and also IME by far the best (thienodiazepine) sleep medication on the market, it has the most euphoria and is the most potent of all the 'benzos' on the market in Belgium

(I actually prefer it over flunitrazepam). It's great and obtainable via a script. So real easy to get your favorite dose (obv) measured, no dissolving in pg & liquid measuring of doses required. Hmm, reminiscing about this epic med is kinda making me feel like I might actually go ahead and try obtaining a box of these sometime soon. I might even try getting brotizolam added to my daily 'diet' when I go see my GP today (or tomorrow at the latest). I'm srsly considering it.

If Brotizolam were available via prescription in Denmark I would have tried to had that added to my 'diet' as you say :P
Clonazepam is the only benzo I absolutely need. The rest I switch around every know and again. For some reason, Alprazolam just doesn't work that well for me. The only times it comes in handy is when I have to stop a panic attack that I can feel starting. The fast onset i handy here, but I cannot "feel" it. It is like eating a placebo just without the placebo effect :P

I really wish they would make Etizolam into a pharmaceutical grade medication available in DK :)

I ended up in the one of the strangest K-holes I have ever tried last night.. One of the things I remember is that I was an 80 mg OxyContin that got eaten and than fell all the way down to the stomach and got absorbed piece by piece. The strange thing is my tendency to (now only mild) depression kinda gets reset after a K-hole. I feel good for a week even up to two weeks. But I am in the group of patient where regular antidepression medication does not fit so I might fit into the studies linking ketamine, glutamat and depression.
 
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Brotizolam might have the potential for an even more potent big brother.

Flubrotizolam ((Flu = R2' fluorine, bro = R7 bromine, ti = thiophene, zolam = triazolo))
2-bromo-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepine

The R2 ring is a fluorine, which we know from Flunitrazepam (5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one) is very potent. The R7 ring bromine is also amongst the most potent as you know from Brotizolam (2-Bromo-4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine) and the bromine together with "9-methyl-6H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepine" which is exactly the same as we have in Etizolam.
So I think it is safe to say that Flubrotizolam posibibly will be amongst the most powerful benzo's that can be designed in the near future. However, we often see in the early life-cycle of a new RC benzo that quantity is valued over quality by the producers, and when this is the case they make mistakes and you end up with something else less potent and maybe even with impurities.

I have seen reports from people claiming to be trying Flubrotizolam and reporting that it is weaker than flubromazolam. But I just don't know if I believe is was reallt flubrotizolam. But as far as I remember, we have an expert on this forum.....roi? I think, maybe I should ask for his input.
 
woke up so fuckin hungover but i got my giro in this morning so popped 600mgs gaba and smoked a ten bag of h

feels better already
 
I'm just saying that - flubrotizolam being better or not, isn't really a concern of mine. Brotizolam is already perfect as far as I'm concerned. (I got it by the way, my doc went along with it quite easily). I am totally broke though. I had JUST enough cash to pay for 30 OC80's, tomorrow I'll have money to fill all my remaining scripts, xanax & brotizolam (and ofc more bromazepam). :)

He gave me:
(my usual) 90x80mg OxyContin
(my newly usual since my last visit with him) 60x2mg Alprazolam
(my brand new, freshly requested & received) 2x30x0.250mg (=250µg) brotizolam. I actually got it, without having to give other benzo up, and all I did was namedrop it in the same sentence as 'trouble *falling* asleep, after that I sleep like a log". 2 awesome and actually the closest to recreational 'zos I've ever encountered.

My psych gives me my bromazepam (and ofc 'done) - my real, functional meds that are under control, and enough to get by with.

My GP, on the other hand, gives me my 'fun meds', namely my oxycodone (contin a.k.a old formula, easily abusable), and also Alprazolam & Brotizolam. All of these can run out early, I don't care. Or.. I (in theory at least :p) should also be able to save my GP-prescribed meds no problem, seeing as I'm able to get by with my shrink's meds for maintenance quite easily.

Happy days! (tomorrow even moreso, that's when papers turn into proper meds.
 
I'm just saying that - flubrotizolam being better or not, isn't really a concern of mine. Brotizolam is already perfect as far as I'm concerned. (I got it by the way, my doc went along with it quite easily). I am totally broke though. I had JUST enough cash to pay for 30 OC80's, tomorrow I'll have money to fill all my remaining scripts, xanax & brotizolam (and ofc more bromazepam). :)

He gave me:
(my usual) 90x80mg OxyContin
(my newly usual since my last visit with him) 60x2mg Alprazolam
(my brand new, freshly requested & received) 2x30x0.250mg (=250µg) brotizolam. I actually got it, without having to give other benzo up, and all I did was namedrop it in the same sentence as 'trouble *falling* asleep, after that I sleep like a log". 2 awesome and actually the closest to recreational 'zos I've ever encountered.

My psych gives me my bromazepam (and ofc 'done) - my real, functional meds that are under control, and enough to get by with.

My GP, on the other hand, gives me my 'fun meds', namely my oxycodone (contin a.k.a old formula, easily abusable), and also Alprazolam & Brotizolam. All of these can run out early, I don't care. Or.. I (in theory at least :p) should also be able to save my GP-prescribed meds no problem, seeing as I'm able to get by with my shrink's meds for maintenance quite easily.

Happy days! (tomorrow even moreso, that's when papers turn into proper meds.

Damn you have a nice combination of prescription medicine. And congratz on the brotizolam script. Please let me know what you think of it in comparison to bromazepam, diazepam, clonazepam and etizolam and clonazolam. Is it hypnotic or more recreational= Is it hard to stay awake and thus be functional on it? Is it a benzo that you can take during the day and still get things done?


The following is a loooot of information about Brotizolam that may or may not interest you depending on how much you are interested in the science behind memory impariment and other benzo effects

I have gathered some different facts for you about Brotizolam
"In clinical trials brotizolam 0.125 to 0.5mg improved sleep in insomniacs similarly to ... flunitrazepam 2mg and triazolam 0.25mg" (Langley and Clissold, 1988 ).
Similarly to Flunireazepam 2mg!!! - That is quite powerful. Please report back to me if this is actually true.

"Brotizolam is an effective hypnotic for hospital patients awaiting surgery, in whom it also reduces anxiety. Brotizolam has an elimination half-life of about 5 hours, which is 'intermediate' compared with the shorter-acting hypnotic, triazolam, and longer-acting benzodiazepines ... Thus, brotizolam is a useful hypnotic which can be used in patients who have difficulty in falling asleep and also in patients who are troubled by night-time awakenings. Used in the recommended dosage it may be particularly useful for patients in whom daytime impairment of performance is unacceptable." Langley and Clissold, 1988 ).

"Brotizolam is a short-acting benzodiazepine indicated as first-line therapy for sleep difficulties. This drug is widely metabolized by cytochrome P450 3A4 in the liver and has an intermediate half-life of approximately 5 h" (Langley and Clissold, 1988 ).

""Brotizolam is quickly absorbed by gastrointestinal tract once being taken orally and usually reaches plasma peak level in 1 hour (0.5–2 hour). Brotizolam has a plasma half- life of 3.1–8.4 hour, which is in the middle of the range from that of ultra-short-acting to long-acting hypnotics. (Yan et al., 2013).[/I]

"Yamadera et al. (2002) evaluated brotizolam efficacy with polysomnography and duration before falling asleep and obtained the results suggesting that brotizolam reduced ratio of REM sleep, significantly increased ratio of Phase II sleep and significantly reduced duration before falling asleep. Studies conducted by Shinomiya et al. (2003) and Suzuki et al. (2003) also indicated that brotizolam reduced sleep latency period in both animal model and healthy volunteers. (Yan et al., 2013).

"Therefore, we argue that the present effects are truly anxiolytic, implicating a reduced level of fear as one of the crucial factors underpinning the behavioral changes in brotizolam" (Yan et al., 2013).

One very interesting finding though the study was done on cows: "Brotizolam injection also accelerated the post-test decrease in plasma cortisol concentrations."
Some reesarchers are starting to abandon the Serotonin-hypothesis in depression studies and instead looking into the relation between glutamate in the brain and depression. In other words, depression is a result of increased concentrations of glutamate in the brain where the stress hormone cortisol might able to increase the glutamate concentration. As such a benzo, or rather a triazolobenzodiazepine, that can decrease levels of cortisol and thus decrease the contration of glutemate in the brain. I am only making my own connections here, I have not looked into whtether this claim can be supported by science. BUT Brotizolam MIGHT be more effective than normal benzo's in the treatment of depression IF you agree in the rejection of the Serotonin hypothesis and instead believe in the Glutamate hypothesis (ketamine research is looking into this).

"Benzodiazepines such as diazepam, lorazepam, are reported to produce anterograde amnesia but these do not affect the retrieval mechanism. Triazodiazepines such as alprazolam, triazolam and brotizolam produce both anterograde and retrograde amnesia. Because benzodiazepine receptor antagonists are known to reverse anterograde amnesia, we wanted to test if inverse agonist can also improve learning and memory.
....
Most of earlier benzodiazepines such as diazepam, halazepam [14,15] are reported to produce anterograde amnesia without affecting the retrieval mechanism [16] while triazolodiazepines, a newer subclass of benzodiazepines, such as alprazolam and triazolam are known to produce both anterograde and retrograde amnesia. Brotizolam, another triazolodiazepine and benzodiazepine receptor agonist [19–21], also functions as platelet activating factor (PAF) receptor antagonist [18,22–25] and exerts hypnotic and sedative activity [26,27]. It has a significant anterograde and retrograde properties [18]. Benzodiazepine receptor antagonists such as flumazenil [17] and CGS 8216 attenuate amnesia induced by various benzodiazepines and triazolodiazepines [28].
...
Results
"Administration of brotizolam at higher doses (0.25, 0.10 and 0.05 mg kg−1 i.p.) significantly attenuated the decrease in ELT recorded during acquisition trials (Fig. 1a) and markedly reduced the time spent in target quadrant (Fig. 1b). These observations suggest that brotizolam produces dose dependent anterograde amnesia" [Input from Ignio: Anterograde amnesia is an impairment to store new memories (black outs like you can experience on Etizolan, Flunitrazepam, Midazolam etc.)].
...
In this study brotizolam required moderate doses (0.1 mg kg−1 i.p.) to produce the complete anterograde amnesia. Similar studies with alprazolam [17] and brotizolam [18] have produced both anterograde and retrograde amnesia in mice

This study showed that norharmane prevented brotizolam induced anterograde amnesia ... Norharmane, however, did not prevent brotizolam induced retrograde amnesia, suggesting that this is mediated through a mechanism independent of the interaction with either MAO-A or benzodiazepine receptors ... In this study, retrograde amnesia induced by brotizolam was reversed by glutamic acid but not by norharmane. l-Glutamic acid did not reverse anterograde amnesia which was reversed by norharmane. It is possible that anterograde amnesia induced by diazepam or brotizolam proceeds with the involvement of presynaptic circuits and glutamic acid participates in the processing of the memory retrieval by involvement of postsynaptic connexions ... Glutamic acid has not only been shown to improve learning in normal mice but in also antagonizing the amnesic effect of diazepam and GABA in step-down test that suggests that increasing GABA-ergic neuronal transmission is unfavorable to learning and memory ... We conclude that anterograde amnesia induced by brotizolam and effectively attenuated by norharmane, and retrograde amnesia induced by brotizolam and reversed by l-glutamic acid, constitutes a significant finding that could help in understanding memory enhancing agents and their targets. "
(Akshay, Saraf and Prabhakar, 2007).


I know this was a very long paragraph. But the main point is that the cognitive impairment seen in in substance abuse and in use of benzo's might be reversed if we get a better understanding of memory enhancing agents. I know that I would very much like to get an understanding of how I can decrease the negative influence benzo's have on cognition.


Due to my stunt with the pharmaceutical fentanyl, oxycodone and morphine I am not likely to get any of these anytime soon. I cannot get prescribed other than methadone (but I love methadone so it is not entirely bad) and maybe tramadol from time to time. I am one of those what really feel euphoric from tramadol, so it is a really nice addition to my daily intake. And speaking of tramadol, I just came home with 100x100 mg tramadol as a friend of mine gets them and want to trade with benzo's and I get more benzo's in a month than I could take in 3 or 4 months, so I really accumulate a lot of benzo's. I dont even haven an overview over the amount of benzo I have stored in a storage room.
 
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I don't have it yet, but I have been scripted it before many, many times. It's equipotent to halcion, yet easier (slightly) to stay awake because it feels so much less sboring, and slightly less like you're getting a big whack on the head with a hammer (causing *lights out* obv).

Also, I made a mistake. Thought today was friday, so I can't get them until tomorrow :(. Which is fine I suppose. :p
 
Well it's been 11 days since I've had any alcohol. Needless to say I am currently drinking alcohol lol. Feels pretty good. Still got a bunch of weed too so I have a feeling I'll throw that into the mix sooner than later.
 
^^^ if u can do 11 u can do 111 in my opinion. but 111 is too long because alcohol is euphoric (again my opinion).
OT: pot dxm caffeine for now. need moar time dilation :O
 
1.0g Heroin
40mg Oxymorphone
80mg Methadone
4mg Clonazepam
2mg Alprazolam
2.0g Gabapentin
20mg Dicyclomine
100mg Promethazine
100mg Hydroxyzine

these opanas by KVK tech kick ass! They feel twice as potent as the others, the one currently on my avatar.

1. K 71 KVK TECH
2. 54 814 Roxane
3. E 795 10 Endo

I love mixing long acting and short acting opiates/Benzos.. the high lasts alllll day. Feeling GREAT.

cheers BL!

You are taking a heroic amount of shit dude. I haven't been gone from this thread that long and you have significantly increased your dosage. Tolerance is such a nasty bitch. I see you haven't posted in a while. You ok?
 
My GP, on the other hand, gives me my 'fun meds', namely my oxycodone (contin a.k.a old formula, easily abusable), and also Alprazolam & Brotizolam. All of these can run out early, I don't care. Or.. I (in theory at least :p) should also be able to save my GP-prescribed meds no problem, seeing as I'm able to get by with my shrink's meds for maintenance quite easily.

mate how do i get a GP like yours!?
mine won't even prescribe me a couple of ambien for a flight ¬¬
 
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