You should reiterate your question and Ask how long it takes for thé brain to run out of phenylalanine as it is the precursor to all the PEA neurotransmetteurs naturally present in the brain because of in what mesure the 5-htp intake blocks other amino acids intake at the BBB, that being the initial cause of dopamine déplétion, (if there is any, which sekio seems to doubr) along other neurotransmetteurs when a supplément such as 5-htp is taken.