To determine how much R/S ketamine is in your stuff you need a device called a polarimeter, basically a fixed-frequency light source and 2 linear polzrizers to see how much the sample rotates polarized light.
Ketamine is only sold as 50/50 mixes or as pure S-ketamine. Nobody sells the R isomer because it is not used medically.
If we are talking about situations where it's definitely a dealer-buyer situation / street buy rather than friends or acquaintances trading more as some kind of equals.... then yes I guess the amount of R-ketamine you will find is extremely tiny. And the abundance of drugs for sale in general will be more the big heavy ones like coke, heroin, speed, weed, and not the stuff nobody has heard of.
Still in my life I have encountered R-ketamine twice, so sekio when you would be inclined to say nobody? Make it 'almost nobody' instead please. Not because I wanna show off. But because of factual accuracy.
The question that now begs me is: does S-isomer synthesis yield R-ket as a separation 'byproduct'? I guess not, its chiral all the way down the path? I'm not sure if there are synth steps that negate chirality... I thought I remembered a phenomenon from orgchem where a transition state compound loses chirality meaning that the endproduct of the reaction is suddenly racemic again. Help me out?
Ohhh wait hold on, I know synth discussion is not allowed but I just saw on Erowid in the Rhodium vault that chirality only arises at the last step. So through separation (using something like chiral tartaric acid to precipitate? Or by sophisticated chromatography?) there is always the R-isomer as waste.
My whole point being: where those Pakistani and Indian megalabs are concerned, a part was and still is being diverted to black market sales... since R-ketamine has some demand there don't you think they would work up at least part of the R-isomer? If only semi secretly.
So I have had the actual stuff and can clearly tell the difference (motor function impairment or lack thereof says enough even without asking, wouldn't you agree?), plus I just illustrated how it's raison d'être is not pointless, unexplainable or implausible.
Back to joining the answering and discussion of the original question: are there different kinds of ketamine and how can you keep them apart?
Two isomers
Well my answer would be, joining sekio and others here: it depends on what you would call different or not.
There are two isomers as is said, both are ketamine but they have plenty of differences but also similarities. And you can imagine you can mix these 2 isomers in any ratio you want, each mix would feel a little different. An equal 50-50 mix is called racemic. Remember this.

So theoretically, there are the 2 pure isomers (imagine them as black and white) and there is a gradual scale going from black to white.
In practice/reality you will find that (what I am totally guessing - but it's an 'educated guess' is) some 85-90% of ketamine you will encounter will be racemic. So it's "grey" from being half white and half black typed.
The left and right hand example is actually much better but not for the gradual scale illustration.
What this means though is that what most people know as ketamine comes from a mix of two somewhat differently acting drugs.
(Isomers of other drugs?)
Let's step back for a moment here and realize that with most or mány other drugs, while the same is true that it is almost all a mix (racemic i.e. the racemate) one of the two types simply does not work! So all the credit goes to the 50% part of it that does work. If the not-working part does not cause significant side-effect or other effect it is simply too expensive to try and leave that part out.
Okay getting back to ketamine: as is now said, there are truly 2 kinds but a third apparent kind which is actually only a mix... is the best known.
Formulations and Preparations
Now a whole other subject arises: ketamine often comes in vials for injection, and they can contain preservatives that can have some minor effect of their own. But in my experience this is never discussed and it doesn't say on any vial I have had.
If ketamine is injected from such vials or cooked into crystal that is used or distributed, some people/dealers/vendors may claim that each brand has it's own characteristics, like pharmaceutical brands of opiates or benzo's are also considered different. Brand is always thought of to be better than generic for example.
It may come down to purity for some part: the proper brands are just made well and are as strong as advertised while generics may be weaker for a variety of reasons.
So truly there are not a whole number of kinds of ketamine as a compound.. but there are
different preparations. This could also be included to mean: there are different batches of ALL drugs, and some are deemed superior to others.
Be aware: on this territory there is a lot of bullshitting. Someone who got me vials in the past offered several brands and described them/advertised them differently in quality. I never believed there was anything but makebelief about those claims except for Agrovet being pure S-isomer instead of the racemate (50/50 R+S mix).
You can check here what is so different between R and S, we have a thread on it!
http://www.bluelight.ru/vb/threads/447697-Ketamine-Subthread-Isomers-R-and-S-Ketamine
Quality or Purity Grades
You mentioned 'human grade' ketamine as a term...
Well for something like tablesalt for instance there are a bunch of purity grades, meant for different purposes and uses:
- raw salt, is least pure and cheapest of all, and is meant for salting the roads when they ice up in winter for instance.
- technical grade would mean it is impure, so people shouldn't eat it, but it doesn't contain little rocks like the raw salt. This can be meant for machines, for instance.
- food grade would mean it is purified enough so that people can eat it. There can be other types of salt in it, but they are not unhealthy like they could be in technical grade
- lab grade would mean it is even much more pure than what is used by people in food. In the lab, some impurities can be a sort of pollution for things that are done that have to keep really pure. For some chemicals there is lab grade and synthesis grade. Synthesis grade is the highest and it is insanely pure and insanely expensive.
For ketamine, I don't know of such an official way of grading but I can at least differentiate between:
- clandestinely made ketamine (this can be impure, but statistically I don't think a significant portion of K is made by small clandestine labs like kitchen meth labs.
- If there are illegal labs, I think they are mostly large but I cannot be sure. You can expect those to have some quality standard...
- Illegally diverted but pharmaceutically made raw ketamine. This is basically pure solid product. It arrives on the black market before going to a vial manufacterer as was officially and originally intended.
- Pharmaceutical K from vials. As legal as it comes but paradoxically it can be impure because like I said they could have mixed it with preservatives, one particularly weird one is a benzo additive, which one that is exactly I'll get back to later.
Since ketamine serves no purpose other than use in humans, all of these can be dubbed 'human grade'. If anything, it's worse than lab grade but you cannot expect that especially not for a fair price.
Does fake ketamine count as ketamine?
Then lastly, there is of course the fact that when someone *says* they offer you ketamine, it may actually be a different drug.
That doesn't mean there are different kinds of ketamine but rather that there are countless possible things that could be sold under the name of ketamine.
Well I said countless, but most things don't feel like ketamine and you would know right away that you have been duped. But there are analogues on the rise and MXE has seen a huge popularity surge. Such things could be mistaken for ketamine.
I will not go into how you can ID your ketamine as being legit.