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How difficult would it be to turn AMT into its HCl salt for stability reasons?

MagickalKat777

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There has been a lot of speculation as to how stable AMT is over a long period of time in its freebase form. A friend of mine in the EU came across a sizable amount of AMT freebase that was freshly synthed but he's concerned about storing it for multiple years.

Is it difficult to convert a freebase into a hydrochloride salt? I have no experience in this department but since I, too, love AMT and the only access I have is freebase, I'm curious as well.
 
Do you think there would be any appreciable loss with this process and if so how would it compare to the loss due to breakdown?

I was under the impression that AMT freebase was pretty stable on its own provided proper storage and I wonder if it would be best to just store it properly. I don't think I've ever read of anyone having dramatic loss of potency over the years, but if anyone knows differently, let me know.
 
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Okay.

So.

Dark vial (obviously would have to be rather large), wrapped in tin foil, stuck in a plastic ziploc with silica packets, in the freezer.

Sufficient enough?
 
Well its not being stored here and EU is quite far out of the reach of the DEA so I'm not worried.

But I'm curious if that's sufficient for storage or if storing that ziploc inside a mason jar is a better idea.
 
That sounds good to me. Depends on the vial of course. A better idea is to store it in a small baggie inside a vial (filling the excess room with water/oxygen absorber). Then the tin foil, then baggie with water absorber, another baggie and then mason jar and then freezer. Probably best youre going to get.
 
Dissolve in alcohol, bubble HCl gas through then evaporate - voila (rough & ready method)

For curiosities sake,

Could you put the freebase aMT into a beaker and cover with DI water (it won't go into solution yet obv). Then add concentrated HCl (aq) dropwise, maintaining good stirring, until the insoluble freebase begins to convert to the salt form (which I believe is water soluble). At some point, all the insoluble freebase should go into solution nicely. Then you can just dehydrate the soln and you have aMT HCl.

Although its a pain in the ass to evaporate water like that, would that be a suitable method? It would avoid the need for HCl (g), which many people are not equipped to handle.
 
why wouldn't you just use a alcohol or some such? seems much easier. also i would figure out the molar ratios so that i don't have excess HCl in the final product.
 
I have a question. since I have alot of AMT freebase and know how good it's smell. Is AMT hcl smell has strong ?

AMT freebase is much stable keep it in dark, cold and low moisture place. I vacuum a jar and store the chemical inside, than I put in a refrigerator until I need.
 
I have a question. since I have alot of AMT freebase and know how good it's smell. Is AMT hcl smell has strong ?

AMT freebase is much stable keep it in dark, cold and low moisture place. I vacuum a jar and store the chemical inside, than I put in a refrigerator until I need.

AMT HCl does not have the characteristic smell of AMT freebase but AMT HCl is approximately 20% less potent by weight and also has different effects and limited routes of administration. Overall, if stored properly, AMT freebase is the better of the two.

AMT freebase IS light sensitive though so you have to watch out for that.
 
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