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Harm Reduction How bad is APAP really?

k20

Bluelighter
Joined
Mar 2, 2009
Messages
195
Around 10pm I took 6 5/500 vicodins which is 3000mg of apap. I plan on taking 7 more vicodins, 3500mg, tomorrow afternoon about 16 hours later. I know the max limit in a 24 hour period is 4000mg, but can it really be that bad? I've taken 5000mg of apap at once before and had no problem at all. If pill bottles say 4000mg is the max limit in a 24 hour period, it's probably stated there because 4000mg is absolutely safe and it would probably be okay even if you ingest more, considering these companies just want to be extra safe and thus just chose a lower number for the "limit". So basically, will I be okay to take an extra 3500mg (6500mg) total in a 24 hour period? CWE is not an option. Now I know this is a harm reduction site, but can someone give me a realistic answer without being overly cautious? Thanks in advance.
 
Out of curiosity why is a cwe not an option? Even if you didn't have everything you need.. One would only need water, container of some sort and a filter.. this could be anything really. coffee filter, even a clean shirt...

Anyway how harmful is it? I guess it depends on the person and how healthy your liver is. I'm not an expert but it's something I wouldn't mess with. Seems risky to me.. I would go the extra step of doing a cwe... better safe then sorry blah blah.. Be safe.
 
I think your logic is flawed friend.
The drug company doing that label might sometimes be like what you think.

Recently I remember reading an article about how they were completely dumb in choosing such high apap amounts in wish hydrocodone back when it was decided, talking about lowering the amounts in the future. I can't find the article now, maybe someone on adderall can do it.

I really think you should just CWE, you get just as high, it kicks in faster, and then you don't have to have a thought in the back of your mind about how you just fucked yourself.
 
it's probably stated there because 4000mg is absolutely safe and it would probably be okay even if you ingest more, considering these companies just want to be extra safe and thus just chose a lower number for the "limit". So basically, will I be okay to take an extra 3500mg (6500mg) total in a 24 hour period? CWE is not an option. Now I know this is a harm reduction site, but can someone give me a realistic answer without being overly cautious? Thanks in advance.

Realistic answer: I think it's really a bad idea to assume that nearly doubling the dose of a drug with extensive known and documented cases of liver failure at the dosages you mention will somehow be safe in your particular case.

APAP is a drug that the general public has been lulled into having a completely false sense of security over. Most people think nothing about swallowing a handful of Tylenol, so effectively have the pharma companies marketed "over the counter" as the same as "safe".

RegisteredStoneeer is absolutely right: there is ongoing discussion about how entwined hydrocodone has become with APAP; it is regretted by the industry and they are, indeed, looking at ways to change the compounds. The real issue, often discussed, is that the line between a safe daily dose, and one that is toxic to your liver, is very very fine. Because of that, there have been many documented cases of APAP-related liver toxicity because many people take, for example, Vicodin and then, without realizing they are supplementing an already high APAP dose, swallow a few "harmless" Tylenlols.

Bottom line: we're talking about your liver. Possibly life-long and devastating damage. And the "safe" dose is indeed within a breath of a toxic one. It seems wise to err on the side of caution, does it not?
 
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^Couldn't have said it better myself. You've only got one liver. Plus there isn't very much harm reduction in us telling you its "safe" to overdose yourself on APAP just so you can have a hydrocodone experience...
 
Realistic answer: I think it's really a bad idea to assume that nearly doubling the dose of a drug with extensive known and documented cases of liver failure at the dosages you mention will somehow be safe in your particular case.

APAP is a drug that the general public has been lulled into having a completely false sense of security over. Most people thing nothing about swallowing a handful of Tylenol, so effectively have the pharma companies marketed "over the counter" as the same as "safe".

RegisteredStoneeer is absolutely right: there is ongoing discussion about how entwined hydrocodone has become with APAP; it is regretted by the industry and they are, indeed, looking at ways to change the compounds. The real issue, often discussed, is that the line between a safe daily dose, and one that is toxic to your liver, is very very fine. Because of that, there have been many documented cases of APAP-related liver toxicity because many people take, for example, Vicodin and then, without realizing they are supplementing an already high APAP dose, swallow a few "harmless" Tylenlols.

Bottom line: we're talking about your liver. Possibly life-long and devastating damage. And the "safe" dose is indeed within a breath of a toxic one. It seems wise to err on the side of caution, does it not?

^^^^^^^^^^^^

Everyone's body is different but the APAP could potentially harm your liver or kidneys in high doses. For some people, even small doses can be harmful and harm is increased without proper hydration.

In regard to laws in the US, I believe the FDA has either mandated or plans to mandate that drug companies reduce the amount of APAP in drugs that contain it because of the potential for serious complications.

CWE is your best bet, regardless, if you have pills with APAP.
 
ACWE is not an option.

I'm honestly curious: why not?

I really am not asking so that whatever answer you give, everyone will jump on you and scoff at your response. I am truly wondering what some of the impediments for people are, or what they perceive to be the reason to not do a CWE.
 
^ yeah there are plans afoot from the FDA to reduce the recommended max dose to 3000mg not 4000mg to try to reduce the risk of accidental OD.

APAP is toxic to your liver, there is no doubt about it (or at least one of it's metabolite is). This explains it better than I can do.. Simply put, the more you take, the more toxic metabolite you produce, and the less able your liver is to deal with it. Liver failure is not pretty, just do a CWE or don't take that much Vicodin, it's simple...
 
If you want to game it, you'll probably survive eating that much APAP. I don't think actue toxicity really sets in until 8-10 grams for most people, not that you'd want to push it.

The best advice anyone will give you is to either wait it out or do a CWE.
 
I'm honestly curious: why not?

I really am not asking so that whatever answer you give, everyone will jump on you and scoff at your response. I am truly wondering what some of the impediments for people are, or what they perceive to be the reason to not do a CWE.

I'm moving so I'm gonna be going back and forth from the house I'm living in and to the new place, moving all the luggage and stuff. My mom and sister are gonna be around at all times pretty much so I'm not gonna have a chance. I got caught for the first time recently so I don't wanna risk getting caught again.

Anyway, thanks for your responses. I know this is off topic but how long does it take for the vics to dissolve in water without crushing them? I've read a lot of cwe threads before but I don't think it covers that. People crush it up before putting it in the water right? And about how much water for 7 pills? I always put too much water I think. If it doesn't take too long to dissolve in the water then I'm willing to give it a shot. If not I guess I'll just wait a few hours before I pop them.

edit: coffee filters are already at the other place :(
 
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You don't need to use that much water. Just use enough so the water level is a bit higher than the level of powder. If you crush the pills, they should dissolve pretty rapidly.. A couple minutes of stirring should dissolve them sufficiently. And you don't need coffee filters. You can take a clean t-shirt, and cover the top of another container (a cup, etc..) and pour your dissolved solution into the new container. Let it drip into it, and then squeeze it to get all the liquid out. The remaining solid mass will be your APAP. Throw this in the trash. Then drink the filtered liquid which will contain your newly filtered, APAP free hydrocodone. Wait a few minutes, and enjoy.

Simple. Just go do it in the bathroom while you're taking a shower. It seriously only takes a few minutes. The longest step is probably crushing the pills.

Seriously, your liver will thank you.
 
Ok thanks everyone. Great idea brokedown :) Mods close this thread if you wish!
 
Well, this differs drastically with what else you are consuming. Taking the amount of apap you are talking about taking by it's self isn't bad for one day. If you did it every day, or every other day for a while, you'd be dead. Keep in mind that 6500mg is nearly a quarter ounce of apap. That's quite a bit. It's enough that it could push you into liver failure on the spot if something was already wrong. Rarely do healthy people with good metabolisms have a problem with this, it's people who have something else going on already. That's something you need to consider. That said, I have seen people take far more apap than 6500mg, but it's sort of stupid to take a big risk with your life like that over a buzz off some 5mg hydrocodone. As for "can it really be that bad" I read a story about a chemist who committed suicide w/ tylenol on this site. If an educated person who is in the field of chemistry uses it to kill themselves, yea it can be that bad.
 
Hey I got an idea, don't get high around your family. Infact, if you have to worry about "getting caught" you should just ditch the shit. All you gotta do is crush them up in a refrigerated bottle of water, then syphon the water off the top, and you don't have to use that much water, maybe 10oz to make sure you have plenty of room to remove the water from the top. My personal method is to crush them up, drop them in a cold bottle of water, shake, let sit for about 5 min so the goop will settle on the bottom, then drink it off the top with a straw. You might get caught when you start throwing up blood from all the tylenol you have been taking, It gave me ulcers. I'll bet you should just listen to your parents, they probably know better on this one than you do if you are eating enough tylenol to worry about your health.
 
A single dose of 10,000mg of acetaminophen WILL be completely fine if your liver is in good health.

Just generally speaking for those with good hepa-health:

If you use CWEs everyday, don't exceed 2000mg APAP daily (but once in awhile a CWE fuckup won't hurt you)

If you use CWEs less than once every week then you can easily handle 4000-5000mg doses.

For a long time living on the street I did Percs (5mg oxy/300mg acetaminophen) everyday with alcohol... so say like 10 beers plus 10-15 percs (3000-4500mg acetaminophen) EVERY DAY FOR TWO MONTHS.

4 years later now and according to blood tests my liver is very healthy.

I understand how stupid it was to do but it's a long, and obvious story.

Just saying, most people worry too much about acetaminophen - which isn't necessarily a bad thing (the worrying).

These days I do full, double filtered CWEs daily.
 
A single dose of 10,000mg of acetaminophen WILL be completely fine if your liver is in good health.

Just generally speaking for those with good hepa-health:

most people worry too much about acetaminophen

I'd really hate for anyone to believe this whole-heartedly.

Liver toxicity from acetaminophen has been reported in otherwise healthy people weighing under 120lbs after approx 8 grams (8000mg).

But the other thing is, does everyone really know the shape of their liver? I don't think anyone should be guaranteeing safety after a 10,000mg dose of APAP - it would be a hell of a time to find out that your liver isn't in the perfect shape you assumed.

I understand that the person who wrote the above post managed to survive their high doses of APAP, but the fact that they were lucky really does not mean that everyone will have the same good fortune.

I encourage everyone to worry as much as they see fit about potentially lethal risks.
 
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I'd really hate for anyone to believe this whole-heartedly.

Liver toxicity from acetaminophen has been reported in otherwise healthy people weighing under 120lbs after approx 8 grams (8000mg).

But the other thing is, does everyone really know the shape of their liver? I don't think anyone should be guaranteeing safety after a 10,000mg dose of APAP - it would be a hell of a time to find out that your liver isn't in the perfect shape you assumed.

I understand that the person who wrote the above post managed to survive their high doses of APAP, but the fact that they were lucky really does not mean that everyone will have the same good fortune.

I encourage everyone to worry as much as they see fit about potentially lethal risks.

I find this to be true, but I would not suggest anyone push that limit. I have mistakenly ingested 14,000mg before. I forgot about my afternoon dosed, then dosed later at 7 or 8pm. I had minor stomach pain, but I freaked myself out and thought I was going to OD on APAP. Which is NOT fun. You can safely ingest 3-4000mg of APAP as long as you arent doing it very often, and you have been well nurished (food, water, etc.)
 
A single dose of 10,000mg of acetaminophen WILL be completely fine if your liver is in good health.

I lost a good bro to a intentional of 8 grams of APAP/codiene i won't go into details but to say he took 2 weeks after the most painful process i have seen - just don't see the benefit in this statement just because your bud survived don't mean he would again it's roulette that all i have to say....M.
 
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