Hormone replacement therapy in the aging population?

JohnBoy2000

JohnBoy2000

Bluelighter
Joined
May 11, 2016
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This is being universally introduced across the UK shortly for women post menopause I believe.

Which seems like a fairly pivotal movement in health care.

I believe post menopausal women are more prone to a reduction in bone density (perhaps explaining the massive increase in joint replacements at that age compared to before it).

I followed an endocrinologist from the US before after watching him on the JRE years ago, called "Mark Gordon".

He was a strong advocate for TRT in men to increase longevity and performance into later years.

Anyone well informed on this area?

Is it a no brainer?
 
JohnBoy2000 said:
Anyone well informed on this area?

Is it a no brainer?
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I mean, what are you trying to ask? Specifically

I don’t care about women and especially not post menopausal ones; but if you’re a male with a T level under 350ng/dl and you’re suffering some classic symptoms of androgen deficiency (libido issues, low energy, brain fog, increased fat mass, generally being an emotional pussy), then yes, TRT will bring you back within the normal range and revitalize you in that aspect. It’s going to require an endocrinology specialist with bloodwork. If you aren’t deficient, no point in it if you don’t compete in bodybuilding.

I don’t support hopping on the shit haphazardly just because of age itself, since that doesn’t always correlate to low T on an individual-case-case basis and a lot of these cases can be reversed with lifestyle changes (that most folks are too lazy, of course, to implement). It’s a good idea if you legitimately need it

That being said it’s not risk free, especially for older men there is a risk of hematocrit going up, prostate problems, etc etc.

Whether or not it’s worth it or a no-brainer is individual dependent. I’d like to see more of a paradigm shift in our society where men are actually men again and don’t just have to rely on synthetic testosterone lol. This shit was not needed in the 60s and 70s. That’s for a multitude of reasons which we could prob dedicate a whole separate thread for I guess

I’ve got over a decade plus of exp with everything under the sun, but that was for bodybuilding purposes
 
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The population wide endocrine dysfunction isn't going away any time soon. Only when we reduce obesity, improve our diets and begin to left heavy things again will we see testosterone levels improve. Xenoestrogens is a whole other beast but it's safe to say they are there for good.

I'm on TRT, 26 and I fucking love it. I'd never go back. But I am tied down to a needle once a week for the rest of my life. Most people aren't willing to make that sort of commitment and it's a serious consideration for ANYONE considering TRT.

There's a lot of talk about reference ranges, numbers, metrics, yada yada. What really matters is this: do you feel good at 300ng/dL? And if you don't, what other issues may you have?

If you feel good, your dick works, you are strong and fit but your total T is 300ng/dL who cares?
 
TheFunkeeJunkee said:
The population wide endocrine dysfunction isn't going away any time soon. Only when we reduce obesity, improve our diets and begin to left heavy things again will we see testosterone levels improve. Xenoestrogens is a whole other beast but it's safe to say they are there for good.

I'm on TRT, 26 and I fucking love it. I'd never go back. But I am tied down to a needle once a week for the rest of my life. Most people aren't willing to make that sort of commitment and it's a serious consideration for ANYONE considering TRT.

There's a lot of talk about reference ranges, numbers, metrics, yada yada. What really matters is this: do you feel good at 300ng/dL? And if you don't, what other issues may you have?

If you feel good, your dick works, you are strong and fit but your total T is 300ng/dL who cares?
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If your levels are too high you're at an increased risk of heart attack and stroke, among other things. THAT'S why you should care.
Sex hormones affect things in your body beyond the obvious; they're a serious medication, not a feel-good drug. I'm on HRT because of an intersex condition, and my levels get monitored with regular blood work.
 
If women start estrogen 7 years after menopause there can be a lot of complications like clotting issues and stroke or MI

Recent looks at old studies have shown that current clinical guidelines to never give women estrogen after menopause have shown the above and hopefully clinical recommendations will change soon because many issues with menopause can actually be prevented with supplemental estrogen when starting menopause, as long as HRT is started within that 7 year window
 
M / 55, I have been on Test Cyp weekly for about 4 years due to extremely low levels (initial test ~68 ng/dL). Have regular blood work and at least 2x/year visits to the urologist whose care I’m under. For me, has been exceptionally helpful and in appropriate conditions, I’d recommend it. Find a reputable endocrinologist and urologist to oversee your treatment….dont fall for the bullshit online services (except those who do just fulfillment) or the “wellness doctors” who will also gladly sell you HGH and a host of other crap you don’t need (not to mention charge you $1K+ for a several-month course of Cyp that costs $75 at your local pharmacy). And, stick with Depo or other name brand or generic test, not compounded. Test Cyp is CHEAP AS FUCK (without insurance), there’s zero reason to go with compounding.
 
P.S. some endocrinologists and urologists don’t do TRT because in the past, it was controversial and in many cases the “Wild West”. Don’t give up. There are a shitload of board certified urologists/endocrinologists who are adept at TRT and have multiple regular patients who are on it. You just have to do your homework and your research.
 
Voxide said:
a lot of these cases can be reversed with lifestyle changes
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Such as?

I've recently absolutely turned my diet upside down.

I call my new routine the "anti-oxidant" diet which makes (obviously enough) anti-oxidants the central component of every meal.

With sufficient protein, carbs and fats for satiety.

So far my skin and hair has began to improve.

Best as I can tell it's the same routine this dude follows:

www.instagram.com

CHUANDO TAN 陈传多 (@chuando_chuandoandfrey) • Instagram photos and videos

2M Followers, 428 Following, 690 Posts - See Instagram photos and videos from CHUANDO TAN 陈传多 (@chuando_chuandoandfrey)
www.instagram.com www.instagram.com

He's 60 but looks about 30.

lG7i92s.png


Simply optimally counter-acting free-radical/oxidation/toxin damage, I assume.
 
TheFunkeeJunkee said:
The population wide endocrine dysfunction isn't going away any time soon. Only when we reduce obesity, improve our diets and begin to left heavy things again will we see testosterone levels improve. Xenoestrogens is a whole other beast but it's safe to say they are there for good.

I'm on TRT, 26 and I fucking love it. I'd never go back. But I am tied down to a needle once a week for the rest of my life. Most people aren't willing to make that sort of commitment and it's a serious consideration for ANYONE considering TRT.

There's a lot of talk about reference ranges, numbers, metrics, yada yada. What really matters is this: do you feel good at 300ng/dL? And if you don't, what other issues may you have?

If you feel good, your dick works, you are strong and fit but your total T is 300ng/dL who cares?
Click to expand...
Why did you get on TRT?

It's under an endocrinologist?

I got my tesosterone checked at 28 and I was about 50 ng/dl above the top reference range (which was 900 and something, I was just below 1000), so the endo said I could actually damage myself going on TRT.
 
JohnBoy2000 said:
This is being universally introduced across the UK shortly for women post menopause I believe.

Which seems like a fairly pivotal movement in health care.

I believe post menopausal women are more prone to a reduction in bone density (perhaps explaining the massive increase in joint replacements at that age compared to before it).

I followed an endocrinologist from the US before after watching him on the JRE years ago, called "Mark Gordon".

He was a strong advocate for TRT in men to increase longevity and performance into later years.

Anyone well informed on this area?

Is it a no brainer?
Click to expand...

Unfortunately synthetically produced estrogen has been shown to increase breast cancer risk.
Natural progesterone in combination with estrogen complements the estrogen/progesterone balance..
 
Im currently trying to get replacement therapy. My insurance is giving me problems. Medicare. Anyway, I scored a 67 on recent bloodwork test. I feel like shit. Im almost 51. Everything is like a laborious chore. Massive fatigue. Idk what to do. Trying to educate myself on test. Hopefully I can get on it soon.
 
Im not sure what im trying to get. Im learning about test and how it works in the body. A lot of it is over my head tbh. I guess just some simple trt if such a thing exists. Seems pretty complicated but as such with the human body. I can get the prescription but just cant fill it yet bc of insurance. Im trying to look into discount stuff like good rx. Seems like online trt is a rip off. Idk. I know I gotta get my test at least back to baseline. I know they'll take awhile but I think even baseline ill feel much better. Im losing my chest hair and my beard doesn't grow nearly as fast. Idk if those are symptoms of low test. I just wanna feel better. I have chronic pain in abdomen so working out hard is kinda out of reality. I can do basic things like bicep curls. Im not looking to get ripped. I just want to have some drive. I have no motivation or energy to do much. Everything is a struggle. My Dr agrees amd says that low scores explains a lot of that. So I just came back here to Bluelight and ive learned a lot over the years so this is my current problem and I know I can learn more out here with everyone's help
 
Satori446 said:
Im not sure what im trying to get. Im learning about test and how it works in the body. A lot of it is over my head tbh. I guess just some simple trt if such a thing exists.
Click to expand...
This post onwards might be insightful.
You might find value in pregnenolone and NDT (natural dessicated thyroid). Your thyroid regulates energy levels, mood, brain function and hormone production. The first hormone we make is called pregnenolone which is available OTC, it's fairly inexpensive. Pregnenolone has numerous theraputic properties which are relevant to your goals.

There's other ways to restore thyroid which I mention in this post, specifically the items described as metabolic repair (the thyroid governs the metabolism).
 
Pregnenolone is great. Subtle colour enhancer and gives you the sleep of angels.
 
Satori446 said:
I ordered sone Pregnenolone. Be here tomorrow. 50mg. Appreciate the suggestion.
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Imo I'd start at a much lower dose, say 5mg or 10mg. Assuming it's in a capsule you can use a fraction of the powder. After using a reasonably small dose give yourself a few days to acclimatise, see whats what etc.

It is better to start small and gradually raise the dose. This allows your body to adjust properly.
 
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Yeah I started taking the 50mg pills but it was way too much - I just take 5-10mg every other day or something. Take a week off every month.
 
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