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Holiday advice????????????????????

L

larson

Bluelighter
Joined
Jan 12, 2012
Messages
35
hello fellow bluelighters.So i have not taking Mdma in over a year due to the anxiety it causes for a few days after i stop partying.Rapid heart beat fear of death time moving in slow motion ye know the way it gets.Anyway i was wondering if i take 5htp the day after will this put a stop to the anxiety.I will also have access to xanax which i will b taking on the comedown if it gets out of hand.Im an experienced raver so i will be testing my shite and taking a reasonable dose.Also i will be drinking heavily on my holiday so can u mix alcohol and 5 Htp? I can handle a regular comedown its the anxiety thats the killer.
 
Drinking too much can lead to 'holiday heart,' which will totally increase anxiety and shitiness from an MDMA comedown. Combining alcohol and 5-htp within too close a time sucks too, as they both work heavily on the serotonin system.

If you're going to combine all that, yeah bring the benzos.
 
Dont plan on drinking too much the day im taking the Md.Will be 6 or 7 hours between taking 5htp and alcohol is this safe?
 
Morphling said:
Drinking too much can lead to 'holiday heart,' which will totally increase anxiety and shitiness from an MDMA comedown. Combining alcohol and 5-htp within too close a time sucks too, as they both work heavily on the serotonin system.

If you're going to combine all that, yeah bring the benzos.
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While I don't know much about alcohol, I didn't think it worked heavily on the serotonin system. I thought it was more to do with GABA & Glutamate receptors.

Personally, I see no theoretical reason why alcohol & 5-HTP isn't safe. I've also tried the combination myself and experience nothing but a usual alcohol high. If I was you, I wouldn't worry about when you take 5-HTP with alcohol. I'd take it whenever it is most convenient to do so.

The 5-HTP could help reduce your shitty hangover symptoms providing you take a decent amount. Try maybe 1-200mg 5-HTP as soon as you start coming down. If that fails at least you've got a benzo on hand to sleep it off.
 
Six or seven hours is enough, yes.

Ethyl alcohol is a 5-HT3 receptor agonist.

I'm not talking out my ass here :p
 
Morphling said:
Six or seven hours is enough, yes.

Ethyl alcohol is a 5-HT3 receptor agonist.

I'm not talking out my ass here :p
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What does that mean? I've no idea what the 5-HT3 receptor does. And why would this interact with 5-HTP?

Just curious.
 
Serotonin is itself 5-HT. 5-HT3 is a specific sub-receptor. They interact due to the fact that working on the same system, causing over-excitement, the result of which can be very uncomfortable side-effects.
 
^

When the receptor is activated to open the ion channel by agonists, the following effects are observed:
CNS: nausea and vomiting center in brain stem, anxiety,[15] seizure propensity [16]
PNS: neuronal excitation (in autonomic, nociceptive neurons), emesis[15]

http://en.wikipedia.org/wiki/5-HT3_receptor
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It's a serotonin receptor, but not one of the common ones. Wiki says it differs from all the others... 5-HTP and alcohol is going to be fine in all likely hood
 
Sure. Just no reason to combine them at the same time. 5-HTP and booze can make you wretch your guts out, among other things. Six to eight hours is enough to avoid that, tho.
 
5-htp + Booze is fine.


5-htp is best before bed...can make you a bit queasy with a decent dose of 300mg
 
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