I assume you are talking about the back of your hand.
This actually used to be my main site to shoot up. I still have a scar from how many times I've used it.
If you can use your arms, that's a better idea. Bigger veins, less risk of damaging surrounding structures. I only used the back of my hand cause I got into the habit of doing it when my veins in my arm had been overused. I've since gotten back into the habit of using the crook of my arm again since a few years not using prior to relapsing has given time for my veins to recover.
So assuming you don't need to use the wrists, it's probably better than you don't. But if you do.... uhhh, tbh I'm not sure what you might be doing wrong other than just generally bad technique. I mean, in my experience it's not especially different to other areas. You wanna be at a shallower angle I guess, since the veins are generally closer to the surface of the skin.
What gauge needles are you using? I usually used 27g and 29g and they worked ok for me. Though that's mainly cause that's what I'm most experienced with since it's what exchanges and pharmacies and such hand out here. Some people might prefer smaller needles.