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  • BDD Moderators: Keif’ Richards | negrogesic

Histamine based itching questions

psynce of sound

Bluelighter
Joined
Aug 14, 2014
Messages
386
As of recent I've begun to dabble with opiates every other week or so. I've been using Oxycodone mostly (40-80mg per dose) and Codeine (300mg). I have past experience with H once and Opium a few times a number of years back.

Now my issue is the itching and scratching whilst on Oxy and Codeine. Will this go away with time? If so how long roughly will it take?

Failing that which antihistamines will deal with itching? When should I take them?
 
Opioid induced itch can be transient or persistent. The full mechanism is not known but histamine release is probably a rather minor contributor. That being said, antihistamines can provide a bit of relief for some and are rather benign, so they probably wont hurt to try. Any antihistamine could do the job but diphenhydramine and hydroxyzine are quite good. You can take them 30-60 mins before the oxy or when the itch starts, if you can stand it. They could potentiate the opiates, increasing analgesia and sedation, so be aware of this.
 
Thank you for the information. I'm going to go for DPH as it is the easiest for me to pick up. What kind of dose should I take? I can get them at 25mg and 50 mg per tablet.
Thank you again.

Oh would anyone know why I vomit when I smoke a cigarette or anything with nicotine contained for a few days after stopping use of oxycodone specifically?
 
Try 25mg first and see if that works.

Nicotine is known for inducing vomiting, and I suppose you are prone to it when you're detoxing from opioids?
 
Try 25mg first and see if that works.

Nicotine is known for inducing vomiting, and I suppose you are prone to it when you're detoxing from opioids?

I shall do that.
Only Oxycodone and Tramadol does this to me. I've never had the same with anything else opiate wise.
The Tramadol does this whilst in effect.
it's really bizarre as it's only occured within the last few months. Admittedly I hadn't used opiates for at least 4 or 5 years previous.
 
Never knew that nicotine was prone to induce vomiting!!

Doesn't IME

Second generation antihistamines (non sedating), work well for me & can also potentiate the opi euphoria.

Rtp
 
I always take one OTC Allegra (180 mg) about 4 hrs before dosing hydro or oxy. This a simple and effective way to reduce the histamine-related itching. The advantage of Allegra is that it won't make you drowsy the way the older antihistamines do.
 
I honestly don't understand why you would want to try and mask the opiate itch. I find the itchiness that comes after a nice shot of H for a few hours is almost orgasmic to me...God do I love to be in the middle of nodding in and out but scratching like crazy. I miss that :( subs don't do shit in way of any opioid side effects besides negative ones....ughhhh
 
Some people dont like itching constantly for hours or unconsciously itch to the point of bleeding, which can be problematic. Im with you, by the way. Love scratching that itch but I have trimmed my opiate use to next to nothing and dont really get it anymore.
 
Some people dont like itching constantly for hours or unconsciously itch to the point of bleeding, which can be problematic. Im with you, by the way. Love scratching that itch but I have trimmed my opiate use to next to nothing and dont really get it anymore.

Yeah I definitely get where you're coming from, but I've personally never taken itching myself to the point of bleeding....it's never that intense at least for me. And btw, I RARELY ever get that itch anymore. Maybe once in a blue moon when I do a few grams of good dope in a day or two. Ever since my tolerance skyrocketed after I went on subs it's almost impossible to have that opiate itch, let alone a God nod....after 10 years of being severely addicted to H, I guess it's a good thing and a thing of the past now...
 
Yeah I definitely get where you're coming from, but I've personally never taken itching myself to the point of bleeding....it's never that intense at least for me. And btw, I RARELY ever get that itch anymore. Maybe once in a blue moon when I do a few grams of good dope in a day or two. Ever since my tolerance skyrocketed after I went on subs it's almost impossible to have that opiate itch, let alone a God nod....after 10 years of being severely addicted to H, I guess it's a good thing and a thing of the past now...

Sometimes I don't mind the itch when it comes with a nod. It can be quite sensual. Most of the time it's a horrible side effect. I've been using opies recently to fight the terrible pain of multiple abscess' in my jaw. So yeah the itch when using them as intended is most cumbersome.
Also I've found 50mg of DPH to work best and as I'm incredibly tolerant to histamine based sedation (thank you mirtazapine for that one) I can tolerate using it in that dose. Though I do push it up to 100mg when I'm on higher dose opies. One thing I'm afraid of is pushing into the realms of delirious effects.
 
OMG, that histamine itch where you (I) feel I might break/rub my fn nose off my face. Then feel it in my legs, scalp... Drives me mad with certain opi's.

Maybe I get it worse, but could never think of it as pleasant!!

Rtp
 
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