Without tolerance, i find ~750ug 25c to provide a good decently strong experience (bucally, complexed) without too much vasoconstriction. Its plenty visual and very euphoric at this dose for me. Any more than that and it tends to get into uncomfortable overstimulation and vasoconstrictive areas. The psychedelic affects are tolerable at higher doses, at least with 25c (1mg) and 25i (1mg), thats to say its not going to mindfuck you into a bad trip, but the side affects will make it something you won't want to repeat often, if at all ime.
25i at 1mg (250ug complexed nasally misted, 750ug bucally) was extremely visual and euphoric, i'd say as far visually as i've ever been on anything. Like 3 second tracers waving your hand around, and heavy digital/geometric overlay on everything. But the side affects are there, they are not fun and taking something to reduce them is not really safe imho. With 25c at that dosage it feels like the same amount of vasoconstriction/muscle tenseness with slightly less stimulation than 25i. Still to much to feel safe for me personally. 750ug is prob as high as i'll ever go with any of the nbomes in the future, even 25b at that dosage had enough side affects to make it my upper limit, perhaps i'd try it once or twice in my life at 1mg but it doesn't feel safe enough to repeat more than that. But to each his own, just don't ever use beta/alpha blockers with nbomes/phens in general to try and reduce the side affects.
Bear in mind i weigh 135lbs, and this is without a tolerance. If i've taken any kind of 25x a week before theres a tolerance, and any non-nbome psychedelic usually has a 3 day window in terms of tolerance ime. The side affects will still be there, that is to say theres no tolerance for the side affects, just the psychedelic affects which makes taking any nbome with any kind of tolerance kind of pointless imho.
Also bear in mind, that blotters do not guarantee your getting what's advertised in ug, there could be patchy distribution and even if you know/trust the person who laid them tread with caution when dosing high. Its not like acid where that would just be an intense blotter, it could be very uncomfortable or life threatening. I only do high doses with blotters i laid individually myself, or nasally at a slightly reduced dosage measured volumetrically, and weighed out 50mg at a time to ensure theres only a max 50ug variance assuming the scale is off by up to 5mg.
High dose nbomes in general is sketchy territory imho. Work your way up slowly, with weeks in between to eliminate tolerance, and be very skeptical about advertised dosages on non self laid/prepared units.