It won't get you high and it's extremely dangerous for your heart to take more than prescribed.I remember talking to a bl poster on irc ages ago called thetripdoctor.
He was explaining at the time how they sell 1000 count bottles of loperamide on amazon and he had taken them to get high.Search results for query: loperamide
www.bluelight.org
The chemical structure is similar to desmethylmoramide. I've never tried a high dose of loperamide personally.