I Hello to all the well meaning people and thanks for all the important information shared here,this is my query,Im a middle aged man ,7 year a deep brain bleed (basically inoperable)From which I am almost completely recovered,I suffered from Chronic pain ,and was prescribed oxy syrup, which I became dependent on,I live in a country with medical cannabis program,and using that, I weaned off the oxy ,only using oxy for extremely bad breakthrough pain ,I can go days or weeks without oxy, but during that time my mood and appetite is terrible,insomnia , but if I take a small amount of oxy,even 1-2 mg daily ( which I dont even feel ) all of that is better, I dont want go down the rabbit hole of dependence again ,what brain chemical am I deficient in?? Is there any medicine to help me?Thank you.