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Heavy 2c-i users: report your adverse effects here

Marauder

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Sep 6, 2010
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Us.. and them.
Acid aside, 2c-i stands as my favorite psychedelic right now. To me, it does feel like a combination of shrooms/acid and MDMA (or at least methylone.)

The come-up is about 40 minutes, at which time I feel nauseous* and have a "wait.. why do I trip? I feel sick as shit" feeling. I get this on shrooms as well. It lasts about 20 minutes where I am either walking or in fetal position to alleviate the bodily discomfort.

* The nausea is reduced if I eat a light meal (i.e., 1 toast, no dairy) 5 mins before or after taking the 2c-i. Meclizine doesn't seem to help.

The following hour is where things get interesting. Visuals kick in hard. Trails, vibrant colors, morphing, swirling, cartoonish faces, shine, exaggerated/cartoony details on people, severely detailed otherwise mundane surfaces, etc. Similar to a high dose mushroom trip or a shroomahuasca trip.

Mentally I become very uplifted. Music sounds heavenly and I become very talkative/social. I get a lot of energy and dancing becomes fluid.

At the peak the external stimuli can become intense enough that I need to be somewhere dark sitting with music on to ride it out.

2c-i comes and goes in waves. There are times where I suddenly feel like I came down, and then without warning begin tripping hard again.

Throughout all of this, I feel 100% in control.*

Now let's talk about side effects from heavy/chronic use.

I take 15-18mg a trip. I have only gone as far as 22-24mg. I am predisposed to psychosis and therefore a deep fear of ego death/high doses. I have had bad trips on most psychedelics and have had my share of high-dose-oh-shit-i-did-it-this-time scares, but I have never had long lasting psychotic effects from any psychedelic. The only drug that has made me truly delusional was caffeine at 800mg.

I don't use 2c-i often under normal circumstances, but got hold of free time and a huge supply and so have been using it a lot. About 4 times a week.

I have no lasting visuals or any other effects except perhaps a positive afterglow. I feel serene, calm, happy for a day or two afterwards. No strange effect on dreams/sleep though taking 2c-i messes with my appetite (I don't eat while tripping, which can be bad) but this is expected. I also feel physically tired when it wears off (but mentally alert.)

I smoke a lot of jwh everyday. I'm always high on jwh or weed or both. There has been no interaction between the drugs except for the fact that when tripping, I can't get high. I feel "higher" than a weed high and so it doesn't affect me much. I can "see" the cannabis headspace as if I am observing it from a distance, but it doesn't necessarily affect my behavior until the 2c-i wears off.

Commonly reported long-lasting effects from 2c-i are HPPD (persisting visuals) and dysphoria/depression or mental instability, esp after a very heavy dose. There is an erowid report of a guy who took 250mg (mistaking it for methylone) and had persistent depression and minor HPPD.

What has YOUR experience been with high doses? To me, the "intensity" in terms of "fuck I'm about to lose my mind! what does that mean? what IS a mind?" mindfuckness of 2c-i at doses of 20mg+ are not as intense as a high dose mushroom trip. It might be because 2c-i comes and goes in waves, and so when I am at the brink of entering a confused psychedelic state, the effects taper down and let me re-orient my thoughts before going back up.

I believe that drugs as potent as 2c-i, which require dosing in the 0.010g range, are very likely to result in negative effects because many users eye ball doses. The difference between a few mg is VERY significant. It's hard to OD on mushrooms because a gram of mushrooms only contains a few mg of psilocybin. A psilocybin extract being spread around to recreational drug users will likely result in negative trip reports as well. I'm not defending 2c-i but this is something worth noting when analyzing people's reaction to this drug on a wide scale.
 
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Ill add something I guess. After a 20mg trip, I did about 5mg of 2ci insufflated for almost a week straight every night just once a day. When I stopped I was beyond emotionally unstable. It was similar to the next-day depression of MDMA or E, but way more like I wanted to cry all day over nothing. It passed after a half week or so. and now I dont really do 2ci much.
 
I love 2C-I but doing it 4 times a week is WAY too much. Even twice a week will get you serious tolerance to the effects. Doing it that often is also going to cause down-regulation of the effected receptors... even once a week on a continual basis will cause that. Not only that but all phenethylamines are strong antioxidants and really tear shit up on a cellular level and are pretty damaging. If you scale back to once every 2 weeks you will enjoy it ALOT more and give your system a chance to recover. No I am not going to list "what exactly are the negative effects of doing this often?" because 1) I would just be spouting speculation as there are no formal studies, and 2) certain people would react "Oh well hell that doesnt sound so bad" and go ahead and do it 4 times a week or more, no matter WHAT side effects were listed. Listen just use some common sense: such things are so powerful and potent and impressive because they exert POWERFUL OUT OF THE ORDINARY FORCED EFFECTS on the release of and response to neurotransmitters. How smart can it possibly be to make them a regular part of your diet every other day or every day? OBVIOUSLY NOT SMART.

See this for advice on recovery/ protection for even rare occasions when you do use this or other phens:

Phenethylamines, Free Radicals, and Antioxidants, Brian Leibovitz, Ph.D.
http://www.maps.org/news-letters/v04n1/04134pea.html
 
And you dont ever feel depressed after dosing 4 times a week?! Wow usually after a 25mg dose of 2c-i i feel pretty depressed the next day.
then again MDMA comedowns make me want to die, and so does cocaine and multiple other drugs. Just my brain chemistry. I think the come down of use that often would send me into a mental breakdown almost.
I only dose 1 psy once a month. if that even.
 
I know of two people who survived both a 50mg 2C-I dosis As pure as can be...

I was one of them..i shrugghed it off afterwards..., i was tripping so hard i didn't realise i was tripping....
 
Aeon Psyche, on 2C-E and 2C-I, after a few hours I feel and believe I am completely sober, but then I look around and realize that I've been tripping so hard for so long that this "soberness" I feel is just me being used to this headset and the visuals. I only realize how hard I was tripping when it wears off completely. Pretty dangerous because in that state I feel fit to drive, but I know better.

DwayneHoover: Thanks for the link. I do take several fat and water soluble antioxidants before, during, and after the trip. I'm more worried about my tobacco habit causing long term brain and organ damage than any of these drugs, not that these drugs are by any means 'safe.'

It's hard for me to say whether I feel anxious/depressed after taking drugs because I'm always depressed/anxious, so to me, when the drugs wear off, I'm back to baseline, even if baseline is so shitty for me.

I don't recommend tripping that often on any drug, but I'm more concerned with 2C-I because all my friends want it and at the price,.. well let's just say we're getting PAID to trip daily (introducing new people to it.) But I'm stopping when I get back on SNRIs in a week. I take SSRI/SNRI vacations every year where I spurge on empathogens-entactogens.

Thanks for the replies. anyone have any other adverse effects to report? How do you guys weight out doses? I used to mix in water and measure out MLs, dosing in teaspoons. Now I have a scale accurate to about 2-4mg ($37 on Amazon. one of the best investments I've made but the scale is fragile.)
 
be careful Marauder.

it seems to be a trend in 2C-I trip reports that usually go like this:
first few trips: magical, everything that a trip drug should be, perfect balance of visuals and empathy
later trips: too much stimulation, mania, visual HPPD symptoms, and loss of empathy

it seems that 2C-I has a "magic" that can be lost with repeated abuse.

If you and your friends really enjoy 2C-I this much, you should treat it with more respect. Don't let your greed overtake your love of mystery and the unknown. Always leave yourself wanting more, and that way you can't run out of things to explore!
 
I know of two people who survived both a 50mg 2C-I dosis As pure as can be...

I was one of them..i shrugghed it off afterwards..., i was tripping so hard i didn't realise i was tripping....


I did 45-50 and survived. It was intense as fuck, but not mind fucking luckily. Imagine the generic hollywood shroom trip, with double vision, rainbows etc. It was like that. Besides HEAVY overstimulation and the urge to constantly piss and shit, I had no negative side effects during, or following the trip.
 
^^ Absolutely true!

My first 4 trips were absolutely magical, and I really, really enjoyed them, 5th was that magical(not comfortable dose and setting). Then I tried more powerfull psychedelics(in particular, 2C-T-2 and 2C-E), and now I have the feeling that I wouldn't enjoy 2C-I anymore. In fact, it is just feeling, and I only had 1 worthless trip(so 6 trips in total). Anyhow, I still hope that I can regain magic with proper setting.

So yes, don't trip too often("often" is different for everyone).
 
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