halogenated THC analogs

[Nexus_Tripper]

Would putting a fluorine onto the end of the amyl chain of THC or the propyl chain of THCV produce an active compound? Halogenating sidechains seem to work well on other cannabinoids.

 

[sekio]

Halogenated analogues of delta8-THC have been made and compared. Potency when you substitute at the 5' position goes like dimethylheptyl > Br = I > trifluoro > fluoro > hydroxy > plain delta8-THC.
[ref]

 

[Hammilton]

Hydroxy is more potent? That's surprising, I wonder how that'd work on the AAIs and the like, seem safer than the fluoro subbed compounds.