Giving up alcohol,. What other drugs are bad for the liver?

[new2drugs]

I know paracetamol is but that's a headache tablet.


Is mdma or cocaine bad for the liver?

Nothing could be worse than alcohol I assume

 

[Jabberwocky]

I can't think of any drug which is acutely damaging to the liver as alcohol.

Most drugs damage your brain or heart before the liver.

 

[neversickanymore]

Certain opiates are bad for the liver.. quite a few of them.

UpToDate

www.uptodate.com

There is much better review out there if anyone wants to chase it down

 

[new2drugs]

Cocaine and mdma are the 2 I may be doing now.

 

[evo4ever]

paracetamol is particularly toxic to the liver

 

[new2drugs]

paracetamol is particularly toxic to the liver

Yes. Which is why I stopped taking it for hangovers.

 

[TheUltimateFixx]

Certain opiates are bad for the liver.. quite a few of them.

UpToDate

www.uptodate.com

There is much better review out there if anyone wants to chase it down

Opiates in and of themselves are not known to be hepatotoxic. All that's mentioned about adverse effects here is risk of accumulation in patients who already have impaired liver function, not that opiates are the cause of it.

 

[neversickanymore]

Opiates in and of themselves are not known to be hepatotoxic. All that's mentioned about adverse effects here is risk of accumulation in patients who already have impaired liver function, not that opiates are the cause of it.

I would look more into this as i don’t think your correct at all

 

[Jabberwocky]

I would look more into this as i don’t think your correct at all

Research suggests some opioid metabolites have potential hepatoxicity, but compared to other drugs or alcohol the risk is quite low.

In general, liver disease associated with opioid use occurs from Hepatitis B/C, not from direct hepatoxicity.

Opioid epidemic and liver disease

Opioid use in the United States and in many parts of the world has reached epidemic proportions. This has led to excess mortality as well as significa…

www.sciencedirect.com

 

[neversickanymore]

I think I have a detailed write up of pain management in people with liver disease saved somewhere.. I pull it up after I’m off the golf course.

 

[Jabberwocky]

I think I have a detailed write up of pain management in people with liver disease saved somewhere.. I pull it up after I’m off the golf course.

The article does mention opioids can exacerbate preexisting liver disease but doesn't suggest it can cause it in a healthy person, at least not commonly.

 

[neversickanymore]

Here is some more info on this

Liver function and Opioids

Opioids in Patients with Renal or Hepatic Dysfunction

The use of opioids in geriatric patients and those with hepatic or renal insufficiency can present significant challenges for clinicians.

www.practicalpainmanagement.com

Safe Usage of Analgesics in Patients with Chronic Liver Disease: A Review of the Literature

Patients with chronic liver disease need special consideration when prescribing pain medications

www.practicalpainmanagement.com

 

[Pissed_and_messed]

Certain opiates are bad for the liver.. quite a few of them.

UpToDate

www.uptodate.com

There is much better review out there if anyone wants to chase it down

Also some RC benzos

Haven't checked studies but I trust coherent people having organ damage and claiming they have source supporting their anecdotal data.