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GHB preload to potentiate MDMA

xyz9876

Bluelighter
Joined
Mar 4, 2013
Messages
51
I have read on 2 seperate occasions on this forum by 2 different members that a small dose (so about 50% of your normal dose) taken an hour before dropping MDMA greatly potentiates the roll (they experienced it). The probable reason for this is that GHB prevents the release of dopamine and dopamine builds up in the brain.
When the MDMA hits, already 2 hours have passed and GHB levels are already greatly lowered and hardly inhibit dopamine release anymore. But now more dopamine is available to release, and this causes one to roll much harder (dopamine is very important for the MDMA experience, serotonin release alone does nothing).
Now I was never tempted to try GHB, but this sounds interesting. Also, because you only take 1 half dose (premeasured) the chances of G-hole are zero. Also this low dose G seems great to get in the party mood and reduce anxiety during the MDMA come-up.

I might try this somewhere my in october/november, as during my rolls in the summer at festivals I want to drink alcohol before my MDMA.

But I wanted to make this topic to see if anyone has experience with this method, and if it improved your roll and in what way? As only 2 seperate experiences are not very reliable.


This is NOT about GHB on the comedown, wich is method many people use, so please don't mention this.

I found one quote:

^ Yeah no real cause for concern, and the "mini-seizures" are perfectly normal when overdosing.
Mixing MDMA and GHB is tricky - ideally you should take G before MDMA, never after - GHB after MDMA hits you like a fucking truck, while taking it before a "roll" potentiates the MDMA by increasing the dopamine rush. You should only take about 50% of your usual dose, wait an hour, and then drop/roll/whatever you call it.
 
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I've never been anxious on the come up while sober, I just start to feel the mdma coming on and im like "aaww yeeeah"
Never tried GHB before MDMA, but I'd say be careful. GHB can be very potent sometimes and its easy to go overboard.
I suggest you look into this more scientifically and then try it out in practice. After all, what works for others might not work for you!
 
Taking hard drugs before a roll is not "preloading", that's taking hard drugs before a roll to make it better.



Also, increased dopaminergic action isn't a very good thing. A large amount of MDMA damage is caused by dopaminergic free radicals causing oxidative stress in serotonin transporters
 
Save the ghb for the comedown IMO. I've never tried it before MDMA but it's one of my favorite things to take after my roll peaks. It's way better than alcohol for the comedown and keeping the party going.
 
^ GHB abuse can lead to serious addiction and withdrawal... not to mention, it can be rather risky in an OD (non-life threatening, but a SHARP dose-response curve). Because of that, I couldn't classify it as anything other than a hard drug! Compared to heroin, it's rather light... on par with alcohol, but still is quite riskier than some other substances



I classify MDMA as a hard drug too though, so don't think about it too much. ;)
 
When used responsibly it's practically harmless though. I can't class it as a hard drug purely because it's made naturally by the body anyway so the body knows how to break it down and it just gets broken down into CO2 and water or something similar, no toxic metabolites. It's got a tonne of beneficial and regenerative effects too.

The reason some people get addicted to it is because it's not heavy on the body at all, because it can be used to help you sleep, go to work, to help with anxiety, to have a good time etc. without leaving you feeling any different the next day some people end up taking it erryday which is ofc a bad idea.

I'd classify MDMA as a hard drug because it's so taxing on the mind and body.
 
Generally speaking, drugs are classified as "hard" or "soft" based on how addictive they are and the physical harm it can cause. Unfortunately that is a very binary reading, and the line for what is "hard" or "soft" is unclear.

MDMA is bad for the brain (4 week minimum recovery), neurotoxic (but not permanently, debatable on this point), but not hugely addictive, and not terribly problematic on the body with fatal overdoses being rare.

GHB is not terribly problematic on the body used responsibly, but quite a bit more addictive. Overdoses *are* an issue with GHB, especially combined with alcohol. The withdrawal is supposedly hellish for addicts. Possibly but inconclusively slightly neurotoxic as well.

They are very different drugs, bad for you in very different ways. Hard or soft? Maybe they're both "hard", but I'd have to then call alcohol a hard drug, and no one does that.
 
When used responsibly it's practically harmless though. I can't class it as a hard drug purely because it's made naturally by the body anyway so the body knows how to break it down and it just gets broken down into CO2 and water or something similar, no toxic metabolites. It's got a tonne of beneficial and regenerative effects too.

That's the same with heroin my friend :)




Maybe we can compromise and call it a Medium drug haha ;)
 
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