Gelato 33 Haze

[sych123321]

Mod please move this. So I hate reading and paying attention . I'm purchasing 4 hits of some strong L. Basically was wanting to know if any of you halfway beginners could tell me if mixing a Hybrid Strain Cannabis with maybe 1 7.5 mg Vicodin be a waste of Opium and money. I know the cannabis is a go but this Vicodin would just be cancelled by the psychadelic right because thry both in a way affect dopamine?

 

[Xorkoth]

Actually opiates dull the effects of psychedelics a little bit, although the combination still works. But neither opiates nor psychedelics work on dopamine. Opiates work on opiate receptors, and psychedelics work through serotonin receptors. And cannabis works through cannabinoid receptors. So they're all 3 working on separate systems. That's a bit of a simplification but close enough.

But if you did mix 2 drugs that worked through the same systems (like 2 different drugs that work on dopamine), it wouldn't cancel them out, it would make them stronger.

 

[sych123321]

Makes it come back to me.

 

[TripSitterNZ]

i have used opiates on acid with weed and didn't notice any dulling.