Opioids Gauging the fallout from the new Opana ER

[mareseatoats]

Are the pharmaceutical industries eventually going to decide to turn every last non-gelling, "Not abuse-proof yet" pill to sewage as well?

They seem to be on a roll with this sort of action.

 

[cyniclove]

SWIM has been introduced to the "new Opana". So far, i've heard it doesn't work well. No matter how much you chew it up, break it down, whatever. SWIM is having the whole "hotcoldhotcold" withdrawal symptoms. They are here for pain, and pain is still wiping SWIM out in all aspects. This shit isn't helping her at all. I mean, even the pupils aren't even constricted in the least bit. I've heard they reformulated it twice. It seems like it's a pill with no active ingredient.

Basically, no symptom relief. No side effects. Absolutely nothing. It's like taking a placebo.

I hope it's not because of the breaking down of the pill? SWIM kind of figured it having more surface area [by cutting it, chewing it, whatever], more would be dissolved at once. This doesn't seem like the case... it's bullshit.

 

[GourmetPez]

I think they will only do it with the super strong ones. They already made fentanyl patches tamper proof(which is a very good thing) but it's not like junkies are the only people snorting pills. No one likes being in pain, especially if it's bad enough to take something this strong. You can't just wait around when you're in agony, that's almost a form of torture.
To the poster above me, I think the OPs had a thing where crushing it made the ingredient inactive so maybe they did it with the new opana er? I'm not entirely sure though

 

[cyniclove]

I think they will only do it with the super strong ones. They already made fentanyl patches tamper proof(which is a very good thing) but it's not like junkies are the only people snorting pills. No one likes being in pain, especially if it's bad enough to take something this strong. You can't just wait around when you're in agony, that's almost a form of torture.
To the poster above me, I think the OPs had a thing where crushing it made the ingredient inactive so maybe they did it with the new opana er? I'm not entirely sure though

I they reformulated all of their pills, strong or not. They also made two strengths obsolete.
5mg, 10mg, 20mg, 30mg, and 40mg are the only strengths now. They removed the 7.5mg and the 15mg tablets.

I mean, doctors prescribe them for a reason. People do have legitimate pain. And this new reformulation doesn't help. And of course if you tell the doctor that they don't help, they will automatically think you're trying to get something stronger and classify this behavior as "drug seeking".

And yeah, TIMERx is the name of the abuse-resistant formula in the OP's and the new Opana is made with. It binds the active ingredient to plastic and makes for a hard, crush-resistant, plasticy pill. It seems like they binded it to some wrong plastic that is indigestible or something, because there's no side effects or anything. SWIM is having withdrawal-like symptoms. Even when taking a moderate dose. This is agony. Complete agony. Pain is still very real and here.

I wonder why they discontinued their first "new" Opana. And then quickly discontinued the first "new" Opana and came out with another "new" one. The only difference is they are bi-concave. They look like the candy Smarties. The older new one looked rounded. Idk.

SWIM had a small bowel resection: three feet of intestine removed. I wonder if that's why SWIM isn't getting relief from this new pill. It's time released so a lot of the release is in your bowels. I've had malnutrition and not being able to absorb pills because of Crohn's Disease and my resection. I wonder if this is why I'm not getting relief. It's a great possibility.

 

[ChronicHD]

Couldn't you plug them? Never done it myself, but couldn't that help your friends from getting sick?

 

[Tommyboy]

And yeah, TIMERx is the name of the abuse-resistant formula in the OP's and the new Opana is made with. It binds the active ingredient to plastic and makes for a hard, crush-resistant, plasticy pill. It seems like they binded it to some wrong plastic that is indigestible or something, because there's no side effects or anything. SWIM is having withdrawal-like symptoms. Even when taking a moderate dose. This is agony. Complete agony. Pain is still very real and here.

I wonder why they discontinued their first "new" Opana. And then quickly discontinued the first "new" Opana and came out with another "new" one. The only difference is they are bi-concave. They look like the candy Smarties. The older new one looked rounded. Idk.

The old formulation used the TimeRX formula. The new ones use INTAC technology formula which is not the same as the older ones with the TimeRX, nor is it the same as the formulation in the 'OP' OxyContin.

Couldn't you plug them? Never done it myself, but couldn't that help your friends from getting sick?

You can't make them into a solution, so you can't plug them. Even if you just jammed the whole pill up there it wouldn't break down, so it wouldn't work.

 

[cyniclove]

The old formulation used the TimeRX formula. The new ones use INTAC technology formula which is not the same as the older ones with the TimeRX, nor is it the same as the formulation in the 'OP' OxyContin.



You can't make them into a solution, so you can't plug them. Even if you just jammed the whole pill up there it wouldn't break down, so it wouldn't work.

Actually, it's called TIMERx-N.
http://www.opana.com/hcp/timerx-n-delivery.aspx

This is the page that tells you the plasma concentrations with each hour.

And I highly doubt plugging them would do anything. They are specifically made to work with your body (when taken orally, they respond to your stomach's pH and since it's supposed to last 12 hours, it travels down your digestive tract for quite some time). Putting it up your ass won't make it break down the way it's designed to, if it even breaks down at all.

 

[Tommyboy]

Actually, it's called TIMERx-N.
http://www.opana.com/hcp/timerx-n-delivery.aspx

This is the page that tells you the plasma concentrations with each hour.

And I highly doubt plugging them would do anything. They are specifically made to work with your body (when taken orally, they respond to your stomach's pH and since it's supposed to last 12 hours, it travels down your digestive tract for quite some time). Putting it up your ass won't make it break down the way it's designed to, if it even breaks down at all.

That's the old formulation though. It says the pills are octagons, so they are talking about the old ones since the new ones are round.

 

[cyniclove]

SWIM is performing a little experiment. Theory: This pill will dissolve into instant release form is you simulate the conditions of the human stomach.
SWIM put one of these in lemon juice (acid).
Observation:
About four hours later, the pill has expanded about 3-4 times its size and it looks like a little white wafer stuck in a pillow of transparent gel.
I'm assuming the outer gel is the immediate release part and the inner white layer is what's supposed to dissolve later.
gel,gel,gel.

Will update about eight hours later.

 

[cyniclove]

after 12 hours, the lemon juice basically ate away at the pill. Left with a lemon juice gunk with little pieces of gel.
Alas, pain relief. I think I defeated the "new" formulation. SWIM feels much, much better. SWIM is elated.
This might cause stomach upset for some. But do not eat any food. Oxymorphone in general (ER and IR) needs to be taken on an empty stomach.

 

[GourmetPez]

You used SWIM and referred to yourself in the same post lol. They don't do all that SWIM/Y stuff here, since it doesn't really protect you at all.
Anyways people have been putting the new opanas in citrus juices, Emergen-C, and Coca-Cola to simulate ph levels in the stomach, and it turns out exactly how you described it. It's a shame it's such a lengthy process for those who are actually in pain. No one wants to set up their doses a day in advance lol, at least I know I wouldn't.

 

[ophead2574]

So let me ask this if you soak it in the lemon juice could you them add in the old IPA methold to prep a shot?

 

[cyniclove]

Tommyboy, I do have to buy lemons and soak them overnight. Lame.
They SORT of help my pain. At least gets me through withdrawals.
Nothing like the IRs. Those helped me achieve the best quality of life. Ugh.

I think the inner white wafer encapsulated in the gel is the good stuff..

 

[80mg]

Why don't you guys just go onto roxicodone? Am i missing something? Why go to triple digit morphine and dialudid and shit when you can just do blues? Yes..its annoying to have 3x thep owder for about 80mg (ha..my name) but the way I see it not much else of a choice. If I was still using I'd just get some micron filters with them...and bang em. Or just snort them. Your choice. IVing has some advantages that snorting doesnt' In my humble opinion its easier to calculate a dose IVing. Like...you shove the plunger down a bit, wait, then if more needed, keep going or chill. Anywhot..just get some fucking roxys. Or get IR Opana (idk why you guys dont just do that)

 

[cyniclove]

Tommyboy, I do have to buy lemons and soak them overnight. Lame.
They SORT of help my pain. At least gets me through withdrawals.
Nothing like the IRs. Those helped me achieve the best quality of life. Ugh.

I think the inner white wafer encapsulated in the gel is the good stuff..

 

[newtoad99]

Hello all. I am new to the forums, well, and to opioids in general, so take it easy on me ok? Reading up on this topic, it seems as if the drug companies are all out to cover their own butts, notwithstanding what pressures, and astronomical effects it will potentiate concerning the people who take their medicines daily. And I don't mean those who "abuse" their wares illegally, I mean those who have a real medical need. Don't get me wrong, I take the word abuse lightly, for I believe whatever a person wants to do with and within their bodies - as long as it doesn't cause harm to anyone else - really should be that persons business.

I never really had a taste for opioids, and have never "abused" them. (in search of a better term) I have, however, been an alcoholic. I should say AM an alcoholic. I haven't drank a drop in over 4 years, but that doesn't make me more less of one. I "abused" the heck out of alcohol, after starting drinking at the age of 12. And yes, the old man knew about it - he was an alcoholic himself. However, it got to the point where I DID cause harm to others, so I had to stop.

Now, fast-forward a few years later. I got injured at work last September. I tore my rotator cuff, broke my wrist, and caused damage to my spine. I have a herniated disk, caused by the accident, at C5 that is impenging upon the nerves in my spinal cord, causing severe pain on my right side, especially in my neck and shoulder region. I also have a herniated disk, which may or may not have been caused by the accident (they can't determine from the MRI's), at T6. I was doing well, for a while, by just taking Lortab 7.5's. A couple of months back my specialist gave me a series of epidural cervical injections. They did not help, and in fact, it seems that the pain has gotten worse. As well, the tingling and numbness has increased. This makes it very hard for me to sleep at night. At the most, I get maybe 2-3 hours per night.

My specialist gave me a prescription for Opana ER. He said it would help with the pain at night so that I could get some rest. I take one 20mg tablet right before bed. Needless to say, I got the new reformulation spoken about, and it DOES NOT help. My tolerance of Narcotics is extremely LOW, so I would think that after only taking Lortab throughout my history of pain, the Oxymorphone should send me through the roof, literally! I can only imagine how it is for those of us who have a much higher tolerance than I to narcotics. I really feel extremely sorrowful for them and the heck that the gov't and the drug makers are putting them through. My heart goes out to you, and I hope that the drug makers will come to their senses.

My specialist said that if the Opana ER doesn't work that he will write me a script for Nucynta ER. I am new to narcotics, as I've said, so I am not very researched on all of the different ones. Is Nucynta ER a good alternative to Opana ER? Do they have it in a formulation such as the new Opana ER? If the Nucynta ER doesn't work, what other options are there? Thanks for your help.

Sorry for being so long-winded, and I hope it is legible. Thanks for creating a forum like this, it really help out those that do not know. Again, my heart goes out to those so devastated by this.

 

[helium-4]

I honestly don't have much sympathy for pain patients who decided to snort their oxymorphone scripts before the change in formulation. They from the start were abusing their medication and are going to have to pay the price of their choice. Obviously if they were taking their medication orally like perscribed then with the new formulation aren't getting as much pain relief they need to discuss this with their doctors, but when they decided they were going to snort their medication they, whether they want to take the responsibility or not, set themselves up for a lot of pain while they have to adjust to a lower quantity of opioids for pain relief.

 

[Jabberwocky]

You can delete it... hit the edit button, (located to the left of the reply button on your post), then the delete button, then it's pretty self explanatory (you can leave the "reason for deleting" box empty if you like, as it's not required you to fill out - although you do need to make sure you've selected the little delete bubble before you hit the final delete button). Haha, if I were you I'd be lost after reading that, but I have a feeling your figure it out. You could always ask a mod to do it if you really wanted to, but it's seriously not hard. And I imagine the mods have enough to do already.

I wonder though, you might share you info with others and maybe even help someone like you out there without worry of it coming back to bite you in the butt as you say.

I don't think anyone will slam you... I mean, you've done NOTHING wrong as far as I can tell (and I'm kinda anal ocd). I've been gone a short while and given the mods running the show I can't believe they'd let it go to all hell like that. At least not in such a short time

But yea, like I said, I bet you can find a way to edit your post and share info (without using SWIM acronyms either). Or you can delete it. It's all good.

I have a question for your though: regardless of how fine you grate (is that the right word?) the pill up, regardless of how small the lines you sniff are, don't you get clogged in the nose/sinuses after sniffing a bit of the new Opana formula? At the least I would expect some CRAZY buggers. Or are you using the old formula?

BTW, if what you describe is working for you so well, you might want to think about using that Opana powder your make rectally. I believe the rectal BA is significantly higher than the intranasal BA, but I'm too lazy to actually look it up atm (I told myself I'd go to be two hours ago and look where I am)...

I don't doubt you, but I don't understand how you're getting your opana to work so well for you though... that is, unless you're using/referring to the old formula...

 

[BeachBum4u]

You can delete it... hit the edit button, (located to the left of the reply button on your post), then the delete button, then it's pretty self explanatory (you can leave the "reason for deleting" box empty if you like, as it's not required you to fill out - although you do need to make sure you've selected the little delete bubble before you hit the final delete button). Haha, if I were you I'd be lost after reading that, but I have a feeling your figure it out. You could always ask a mod to do it if you really wanted to, but it's seriously not hard. And I imagine the mods have enough to do already.

I wonder though, you might share you info with others and maybe even help someone like you out there without worry of it coming back to bite you in the butt as you say.

I don't think anyone will slam you... I mean, you've done NOTHING wrong as far as I can tell (and I'm kinda anal ocd). I've been gone a short while and given the mods running the show I can't believe they'd let it go to all hell like that. At least not in such a short time

But yea, like I said, I bet you can find a way to edit your post and share info (without using SWIM acronyms either). Or you can delete it. It's all good.

I have a question for your though: regardless of how fine you grate (is that the right word?) the pill up, regardless of how small the lines you sniff are, don't you get clogged in the nose/sinuses after sniffing a bit of the new Opana formula? At the least I would expect some CRAZY buggers. Or are you using the old formula?

BTW, if what you describe is working for you so well, you might want to think about using that Opana powder your make rectally. I believe the rectal BA is significantly higher than the intranasal BA, but I'm too lazy to actually look it up atm (I told myself I'd go to be two hours ago and look where I am)...

I don't doubt you, but I don't understand how you're getting your opana to work so well for you though... that is, unless you're using/referring to the old formula...

Thanks for the info! No, it's not the old ones, they are the new ones. Yes, I do get some cloggers but I sniff it back pretty good and leave it for quite awhile so it can be absorbed. After a couple hours, I do the ole' one nostril blow and get that stuff out of there. Then I do more. I keep on a pretty level keel, like I said, unless I wish to crank it up a little. And to answer your suggestion of the plug bit, ah ah NO WAY! That hole is "exit only" and I'm not putting anything up there, even drugs. This is working for the time being, so I'm going to roll with it. But thanks for the reply.

 

[Lynx2525]

My guy in TJ sells the old ones . Pricey, but worth it! I can't stand any of the er's! Could a member with a degree in chemistry work on this problem? Please !!!!!