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  • BDD Moderators: Keif’ Richards | negrogesic

Gabapentin please describe

I recently discovered low doses of pregabalin can be useful for neuropathic pain. So, it’s not such a useless drug for me after all. Unfortunately, even at low doses (50mg) I felt sedated and dumbed down, and was clumsier.
 
fairnymph said:
Baclofen is not like Flexeril at all. I despise Flexeril and I find it totally useless. It just knocks me out for like 16 hours, leaving me groggy for even longer, and has no pleasant effects or muscle relaxation. Baclofen is very weak - but then my muscle tension and spasticity is extremely severe - but it does have some effect unlike Flexeril, and no sedation. Even more effective is carisoprodol, but nothing I’ve tried - and I have tried everything that might possibly help - compares to diazepam for muscle tension.

Gabapentin does help for sleep by the way. Ativan is not sedating for me at all.

The only things that actually helped to relieve the cause of my back pain:
1. diazepam
2. carisoprodol
3. baclofen & clonazepam
4. gabapentin

But everything below one and two has such a minor effect it’s barely worth taking - only if I can’t get one or two. And as I said, diazepam is by far the most effective. But everyone is different so you may need to try many things to find what works best for you. I have never found weed remotely therapeutic and I don’t enjoy it recreationally either.
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Maybe your doses were conservative? I've been wondering about baclofen as an anxiolytic that might have synergy with other meds I take to cause inhibitory effects in the CNS. I have a permanent tolerance to gabapentin and pregablin due to regular abuse. I could take several thousand mgs of pregab with minor effects even after a long break.
 
Conky said:
Maybe your doses were conservative? I've been wondering about baclofen as an anxiolytic that might have synergy with other meds I take to cause inhibitory effects in the CNS. I have a permanent tolerance to gabapentin and pregablin due to regular abuse. I could take several thousand mgs of pregab with minor effects even after a long break.
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What is the dose of baclofen for anxiolytic effect and will it work if it's expired?
 
So weird that you needed that high of a dose for a first go but then once again just proofs that we all nit the same and that we need to be carefully and do proper research if you want to do a chemical foe recreation value and so on.

The very first time I had pregabalin I had 225mg. That had ne happy, laughing and styling around.
 
flipflopper said:
What is the dose of baclofen for anxiolytic effect and will it work if it's expired?
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I'm not sure as I haven't tried it yet and everyone responds differently. But I've researched it a lot and have concluded that standard dosing such as 10mg 3x daily won't be enough for me. I would ask my doctor to start with 50mg daily and increase based on response.

If you have expired baclofen, it might have lost some potency depending on how long it's been. I have some quetiapine leftover from 2023 and I swear those pills feel weaker than the current pills I'm getting.
 
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Conky said:
Maybe your doses were conservative? I've been wondering about baclofen as an anxiolytic that might have synergy with other meds I take to cause inhibitory effects in the CNS. I have a permanent tolerance to gabapentin and pregablin due to regular abuse. I could take several thousand mgs of pregab with minor effects even after a long break.
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I started at lower dose, but high doses were not any more helpful. I did not notice any anxiolytic effects. Flexeril & other supposed muscles relaxant do have an effect on me, just not remotely a muscle relaxing effect. They are extremely sedating; they knock me out for many hours and leave me groggy for more.
 
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I found on days that when I used gabapentin for recreational purposes then never really take my benzo and for a day or 2. It definitely for me holds anxiolytic properties.with no rebound in between swapps whether the time period of the switch.
 
Conky said:
I found the stats page on pubmed and it mentioned baclofen off label for helping with alcohol abstinence and alcohol related anxiety.

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I know that it helps with alcohol wds but nothing about anxiolytic properties nut if that state it does but not clearly om dosage wise or ways. It kinda stops there and that where self experimentation happen that either turning out good or bad for the user but I personally can't help anu further. Any reason you wanted to use baclofen specifically and are you heaving severe moment and durations or is it a new thing that's triggering it. Sorry sometimes some back story helps to solve or just recognize the problem.
 
Coffeeshroom said:
I know that it helps with alcohol wds but nothing about anxiolytic properties nut if that state it does but not clearly om dosage wise or ways. It kinda stops there and that where self experimentation happen that either turning out good or bad for the user but I personally can't help anu further. Any reason you wanted to use baclofen specifically and are you heaving severe moment and durations or is it a new thing that's triggering it. Sorry sometimes some back story helps to solve or just recognize the problem.
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I'm wondering about baclofen due to it's GABA B activity and the resulting modulation of excititory neurotransmitter release. My gaba b receptors are essentially untouched by exogenous substances/ligands unlike gaba a.

I am prescribed several medications including Sertraline, Loxapine, Lorazepam, Zopiclone, Lemborexant, Clonidine and PRN Quetiapine. Most of that is taken at bedtime and it doesn't keep me asleep unless I misuse the prn.

Everyday around 2pm I start getting into an edgy/anxious mood with what I assume to be rebound hypertension. It is explains the warm and flushed cheeks. And that happens after taking a 0.1 clonidine. I have to take it along with 5-10mg loxapine and 25mg quetiapine. Other wise the rest of my day will suck until the bedtime meds.

And I'm interested in any medications that might help me without messing with prolactin and or other hormones
 
fairnymph said:
Baclofen is not like Flexeril at all. I despise Flexeril and I find it totally useless. It just knocks me out for like 16 hours, leaving me groggy for even longer, and has no pleasant effects or muscle relaxation. Baclofen is very weak - but then my muscle tension and spasticity is extremely severe - but it does have some effect unlike Flexeril, and no sedation. Even more effective is carisoprodol
The only things that actually helped to relieve the cause of my back pain:
1. diazepam
2. carisoprodol
3. baclofen & clonazepam
4. gabapentin
Click to expand...
I used to take Flexeril with opioids and really didn't feel much different, it was just in my grandma's med cabinet (she didn't use them, I'm not that shitty). Is it common to pass out off it? I mean I might have nodded a bit more but it was a pretty heavy pill phase so I couldnt list everything if I tried, so there's not much to say on that.
fairnymph said:
But everything below one and two has such a minor effect it’s barely worth taking - only if I can’t get one or two. And as I said, diazepam is by far the most effective. But everyone is different so you may need to try many things to find what works best for you. I have never found weed remotely therapeutic and I don’t enjoy it recreationally either.
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I was gonna ask if the gabapentin was really helpful until I read this at the end. Kinda what I thought. How often can you personally take it? I feel like by the second day it does nothing.
 
daturetard said:
I used to take Flexeril with opioids and really didn't feel much different, it was just in my grandma's med cabinet (she didn't use them, I'm not that shitty). Is it common to pass out off it? I mean I might have nodded a bit more but it was a pretty heavy pill phase so I couldnt list everything if I tried, so there's not much to say on that.

I was gonna ask if the gabapentin was really helpful until I read this at the end. Kinda what I thought. How often can you personally take it? I feel like by the second day it does nothing.
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It’s common for so-called skeletal muscle relaxants to knock people out, but I do seem to be a little extra sensitive to this effect.

I don’t ever take gabapentin, unless I’m out of more effective muscle relaxants or going through opiate withdrawal, because all GABAergics have cross-tolerance and keeping my diazepam tolerance down is of paramount importance. So typically I only use diazepam 90% of the time. And I can’t get carisoprodol over here, or I’d probably alternate that and diazepam. But everything else is really not worth using because the muscle relaxant effect is so weak.
 
Gabapentin please describe: 400 mg, kind of a tan/sick orange color with the number 214 and a capsule 2 cm long and filled with a horrible tasting white powder.
 
Sertraline =ssri
Loxapine = atypical anti-psychotic
Lorazepam = benzo
Zopiclone = z drugs
Lemborexant = orexin receptor antagonists also for sleep
Clonidine = is an α2A-adrenergic receptor used to treat high blood pressure and helps with wds
PRN Quetiapine = atypical anti-psychotics

Those are the meds you describing taking and that's a handful and what are you actually in reality to achieve by taking all these meds.
 
Coffeeshroom said:
My 400mg capsules is also off tan orange with the nr 139 on it. Brand name epileptim
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Oh, you are all fancy with the brand name, mine are generic.☹️
Coffeeshroom said:
Sertraline =ssri
Loxapine = atypical anti-psychotic
Lorazepam = benzo
Zopiclone = z drugs
Lemborexant = orexin receptor antagonists also for sleep
Clonidine = is an α2A-adrenergic receptor used to treat high blood pressure and helps with wds
PRN Quetiapine = atypical anti-psychotics

Those are the meds you describing taking and that's a handful and what are you actually in reality to achieve by taking all these meds.
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Sorry apologies I should have quoted that the last one as it was meant for the op. As I was listing this as he was asking about anxiolytic effects of baclofen and with what he listed tak8ng there should be already enough anxiolytic relieve.

Are you talking to me.☠️🤬☠️ lol?
 
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I love gabapentin. Taken very sparingly it can create a great mood. (3 times a month, 1500 mgs staggered) And I am creative, at least with music. Took some tonight after a shit week and I feel great. That is why I am posting. I still get an afterglow the next day too. Very glad I decided to not take daily. I does help with my shoulder pain and I take much less ibuprofen.

Family and people around me that take it that are not part of BL never talk of effects or withdrawal. I always found that fascinating. But it still made me careful.

Gabapentinoids became a valid class of drugs. Years ago people would have laughed.
 
JackARoe said:
I love gabapentin. Taken very sparingly it can create a great mood. (3 times a month, 1500 mgs staggered) And I am creative, at least with music. Took some tonight after a shit week and I feel great. That is why I am posting. I still get an afterglow the next day too. Very glad I decided to not take daily. I does help with my shoulder pain and I take much less ibuprofen.

Family and people around me that take it that are not part of BL never talk of effects or withdrawal. I always found that fascinating. But it still made me careful.

Gabapentinoids became a valid class of drugs. Years ago people would have laughed.
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Interesting that you mentioned the afterglow the next day because I took it last week and I did notice that but thought maybe I was imagining it. I was cool as a cucumber for most of the day, like the way I would like to be all the time, like nothing phased me. It was an amazing experience.
 
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