Fornax55
Bluelighter
- Joined
- Jun 17, 2010
- Messages
- 466
Title pretty much speaks for itself. I've been talking to some members of my community who are far more involved in the drug distribution scene than I am as a simple recreational user. However, with a decade and a half of pharmacological self-study under my belt, even those who are pretty high up in the chain of command come to me for questions about pharmacodynamics and shit.
Currently I'm trying to figure out how we could produce some sort of dope that's strong enough to satisfy the addicted population and inherently incapable of producing a fatal overdose. My first thought was to include some sort of respiratory stimulant, akin to the way that nature tossed thebaine into the opium poppy to help prevent what I'm talking about. (Hold on, wait - maybe that's the answer that I need? If anyone could chime in on the plausibility of including thebaine in fentadope to prevent ODs, please do). Or to use some sort of opioid antagonist that's potent enough to bump off fentanyl and its analogs but with a binding affinity just strong enough to allow for a strong buzz.
Another suggestion given to me was to crystallize the substance present in an asthma inhaler and mix that in with the dope. I have no idea about that. Doesn't sound like a safe idea but I could be wrong.
There's also ongoing debate as to what "benzos" are actually included in what is commonly referred to on the street as "benzo dope." Knowing that most benzos aren't easily vaporized makes me a bit of an outsider when I try to tell people that their product doesn't contain what they're telling people it does, or at least asking them to specify what benzo is in it only to find out that they think "benzos" is actually the name of a drug. Smh.
The only thing I can think of that might match the feeling produced by "benzo dope" is etizolam, which can be sourced easily enough. We've entered a time when there's an entire generation of "heroin addicts" who have never actually tried heroin. Etizolam and enough of a potent mu agonist to fight off withdrawal would certainly satisfy their cravings. But then we have people overdosing on "benzos" all over the place with people shoving a dozen vials of narcan into their arms and wondering why they won't wake up.
Preventing overdoses is another matter entirely, though. Are there any opioid agonist/antagonists similar to buprenorphine that only exert antagonism after providing enough agonism to produce a strong buzz? Are there any rate-limiting opioids? Vape-able respiratory stimulants that wouldn't interfere with the quality of the buzz, but would keep someone breathing after they've passed out from an opioid and/or benzo overdose?
Any input would be much appreciated. I did learn a bit from this thread but was disappointed to see the lack of responses.
Currently I'm trying to figure out how we could produce some sort of dope that's strong enough to satisfy the addicted population and inherently incapable of producing a fatal overdose. My first thought was to include some sort of respiratory stimulant, akin to the way that nature tossed thebaine into the opium poppy to help prevent what I'm talking about. (Hold on, wait - maybe that's the answer that I need? If anyone could chime in on the plausibility of including thebaine in fentadope to prevent ODs, please do). Or to use some sort of opioid antagonist that's potent enough to bump off fentanyl and its analogs but with a binding affinity just strong enough to allow for a strong buzz.
Another suggestion given to me was to crystallize the substance present in an asthma inhaler and mix that in with the dope. I have no idea about that. Doesn't sound like a safe idea but I could be wrong.
There's also ongoing debate as to what "benzos" are actually included in what is commonly referred to on the street as "benzo dope." Knowing that most benzos aren't easily vaporized makes me a bit of an outsider when I try to tell people that their product doesn't contain what they're telling people it does, or at least asking them to specify what benzo is in it only to find out that they think "benzos" is actually the name of a drug. Smh.
The only thing I can think of that might match the feeling produced by "benzo dope" is etizolam, which can be sourced easily enough. We've entered a time when there's an entire generation of "heroin addicts" who have never actually tried heroin. Etizolam and enough of a potent mu agonist to fight off withdrawal would certainly satisfy their cravings. But then we have people overdosing on "benzos" all over the place with people shoving a dozen vials of narcan into their arms and wondering why they won't wake up.
Preventing overdoses is another matter entirely, though. Are there any opioid agonist/antagonists similar to buprenorphine that only exert antagonism after providing enough agonism to produce a strong buzz? Are there any rate-limiting opioids? Vape-able respiratory stimulants that wouldn't interfere with the quality of the buzz, but would keep someone breathing after they've passed out from an opioid and/or benzo overdose?
Any input would be much appreciated. I did learn a bit from this thread but was disappointed to see the lack of responses.