Flynalbarbital (Fluoromethylpentylal)

[Hammilton]

I see 40 to 50mg/kg of pentobarbital, along with an opioid as being an effective dose for euthanasia. That's not terrible. That's what, 2.5 to 5 grams? That's hardly bad at all.

I don't see any reason why more potency is needed. I mean, if the bitter taste is too much a problem, there are other routes of administration.

Barbiturates may be effective drugs for euthanasia, but when it's time for me to go, I'll be choosing an opiate, a benzodiazepine and an antihistamine (the first two to ensure lethality and the antihistamine to relieve the unpleasant physical effects of the overdosed opiate).

 

[planckunit]

The drug is defintiely not explosive, in fact this was one of the things discussed in the white paper, and it was cleverly designed so it would never be dangerous in that regard, but I don't think the 3rd position of the ring was charged as appeared in the first image I provided. In the second image, it's just the raw barbiturate we are looking at, not it's sodium salt, but the first image appears to be wrong according to the white paper specs, and the newer image appears to be the correct one, but for an image of the sodium salt, you'd simply write Na+ and pick either the 1st or 3rd position and negatively charge it which in the case of F would be F- and in the case of HN would be N-. I am not entirely sure if it is the 1st or 3rd position that is negatively charged, but someone with a deeper understanding of barbiturate molecular structures could help point out any obvious inadequacies in my explanation.

I think this is a troll post on a compound that doesn't exist and if it would exist is probably not suitable for human use

 

[amanitadine]

. . .

Barbiturates may be effective drugs for euthanasia, but when it's time for me to go, I'll be choosing an opiate, a benzodiazepine and an antihistamine (the first two to ensure lethality and the antihistamine to relieve the unpleasant physical effects of the overdosed opiate).

Right with the there Ham, having experienced a non fatal overdose of this triumvirate years ago It would be a pretty pleasant way to go. Some states used to incorporate ketamine into the lethal injection cocktail, maybe still do, dunno, but this would be the icing on the cake. A good 250 mg IM followed 20-30 minutes later by the aforementioned cocktail, delivered slowly enough to dramatize the k hole of no return. Mmmm.

 

[Flynnal]

I think this is a troll post on a compound that doesn't exist and if it would exist is probably not suitable for human use

Troll post...nope...the compound indeed exists, under the name fluoromethopentylal obviously as it's sodium salt. Someone at one of the euthanasia blogs mentioned that they obtained 0.5g of the stuff and said that 100mg gave them a hangover that lasted 2 days. I'm not sure how they got their hands on it. I don't care much for 2-day hangovers, and, as someone else in this thread mentioned, being a methylated and halogenated amide it may not be good for your liver at all. Claims of it being twice as potent as Nembutal wouldn't be far off. For starters the methyl bond at position 3 of the ring will make the drug much more potent, provided that it's R2 side chain is complex enough, and pentyl chains have a reputation for producing powerful barbiturates ie Amytal, Nembutal, Seconal, all share a pentyl R2 chain. The fluorination would increase the drug's half-life and pharmacological effects.

 

[jambabomba]

Does someone know how would these compare to benzos? Ex. Diazepam. What would be equivalent dose?

 

[Flynnal]

50mg of this would compare to about 30-40mg of diazepam.

The problem with comparing barbs to benzos is that barbs produce a different type of body effect, so it's difficult to compare them. On the surface, 30-40mg diazepam would be about right.