Flynnal
Bluelighter
- Joined
- Aug 14, 2012
- Messages
- 940
UPDATE: New molecule image. I was able to find another image of this molecule on my PC. It appears to be more correct than the one initially used in the post. I don't understand why there were two separate images, but I was able to obtain some more information about the substance.
Not so long ago I found this designer barbiturate molecule that turned up out of nowhere. But soon after it disappeared, I tried to find the link again, but never succeeded, so gave up.
BIN: Flynalbarbitone INN: Flynalbarbital...also named under Fluoromethylpentylal or Flynalbital
But I thought I'd copy a picture of the molecule and keep it for posterity. This looks like a halogenated barbiturate derivative, and looks like secobarbital/pentobarbital in that it has a pentyl group for the R2 chain. The 3rd position of the pyrimidine ring looks interesting. It is a fluorinated methyl group.
This was the old molecule image, which appears to be wrong, even though the R2 side chain is a pentyl type chain.
The molecule is supposed to look like this.
Again, these links are just my copies of these images, the original link had information about the barbiturate, including information about it's toxicity, half-life, effects, potency, and estimated MLD.
Half life: 60-100 hours
Toxicity: Extremely high, MLD is a mere 600mg (0.6g) for an average adult male (estimate only) - compare Nembutal/pentobarbital at 1000mg (proven).
Duration of action is anywhere from 10 to 30 hours, which means this is really a long-acting barbiturate, but it's sedative/depressant effect is said to be 2-3 times more potent than that of secobarbital in equivalent dosage (80mg secobarbital compared to 80mg flynalbarbital) - and this molecule reminds me of methohexital which is the most potent barbiturate to my knowledge, except clearly we're looking at a pentyl group here.
This active drug was called by the name of Flynnal Sodium and was to come in 10mg (pink), 20mg (green), 40mg (blue) and 80mg (white) tablets, with some umming and ahhing about the release of 80mg tablets due to the obvious suicide risks, and would come in small packets of 5 tablets and larger packets of 25 tablets. One group who tested the tablets for various things, including the taste, claimed that the tablets were laced with Bitrex (Denatonium). However, laboratory analysis were undertaken and the tablets contained no traces of denatonium. After that conclusion, they claimed this drug was significantly more bitter than the barbiturate Nembutal (3-4 times more bitter by memory), and assumed the bitterness was perhaps reflecting the alleged toxicity of the drug.
The effect was your classic barbiturate sedative-hypnotic effect, just much stronger than your typical barbiturate drug. After taking 80mg one subject claims he felt like his weight had gone from 100kg to 300kg and was so sedated he could barely move. He slept for 14 hours straight, according to the write up. One user took 40mg and claimed that after an hour he felt it had the same effect as 260mg of phenobarbital. Another user who took 120mg reported vertigo, effects on his "working" memory, and nausea ending with profuse vomiting. One female took 40mg and was "smashed after an hour", while another user took 40mg in total (20mg and another 20mg an hour later) and he felt it was similar to him being affected by alcohol. So, going by those texts, I would assume that the toxicity would at least be partially validated and that one of these users could have indeed died from ingesting 600mg.
Pentyl groups, at least it seems, tend to produce the most toxic of barbiturates, and because this drug appears to be fluorinated, thereby inhibiting it's metabolic mechanisms, its toxicity could increase, but a MLD of just 600mg seems a tad low for a barbiturate. Virtually all barbiturates start at ~1.5g for a MLD, with one notable exception - pentobarbital which is said to be ~1g.
Strangely enough, I used Flynnal as my pseudonym on this forum.
Tell me your thoughts. It looks like a very strange drug, and in this day and age, I'm beginning to wonder if barbiturates are being taken off the back burner and coming back on to the market. Flynnal would be the ideal anxiolytic in the context of panic attacks, and would, at least going by it's toxicity, make a damn fine implementation for physician assisted suicide, and would replace Nembutal if it were not for it's disgustingly bitter taste according to the texts - I would say that simply reducing the amount of the drug taken as a drink (a la Dignitas) with added strong sweeteners would make it more palatable for that application. We all know barbiturates are bitter, but I can't even imagine what something 3-4 times as bitter as pentobarbital would taste like, pentobarbital sodium tastes absolutely revolting! (going from memory of trying pentobarbital years ago, I emptied the capsule and took the powder for a laugh - the worst thing I'd ever tasted!)
Not so long ago I found this designer barbiturate molecule that turned up out of nowhere. But soon after it disappeared, I tried to find the link again, but never succeeded, so gave up.
BIN: Flynalbarbitone INN: Flynalbarbital...also named under Fluoromethylpentylal or Flynalbital
But I thought I'd copy a picture of the molecule and keep it for posterity. This looks like a halogenated barbiturate derivative, and looks like secobarbital/pentobarbital in that it has a pentyl group for the R2 chain. The 3rd position of the pyrimidine ring looks interesting. It is a fluorinated methyl group.
This was the old molecule image, which appears to be wrong, even though the R2 side chain is a pentyl type chain.
The molecule is supposed to look like this.
Again, these links are just my copies of these images, the original link had information about the barbiturate, including information about it's toxicity, half-life, effects, potency, and estimated MLD.
Half life: 60-100 hours
Toxicity: Extremely high, MLD is a mere 600mg (0.6g) for an average adult male (estimate only) - compare Nembutal/pentobarbital at 1000mg (proven).
Duration of action is anywhere from 10 to 30 hours, which means this is really a long-acting barbiturate, but it's sedative/depressant effect is said to be 2-3 times more potent than that of secobarbital in equivalent dosage (80mg secobarbital compared to 80mg flynalbarbital) - and this molecule reminds me of methohexital which is the most potent barbiturate to my knowledge, except clearly we're looking at a pentyl group here.
This active drug was called by the name of Flynnal Sodium and was to come in 10mg (pink), 20mg (green), 40mg (blue) and 80mg (white) tablets, with some umming and ahhing about the release of 80mg tablets due to the obvious suicide risks, and would come in small packets of 5 tablets and larger packets of 25 tablets. One group who tested the tablets for various things, including the taste, claimed that the tablets were laced with Bitrex (Denatonium). However, laboratory analysis were undertaken and the tablets contained no traces of denatonium. After that conclusion, they claimed this drug was significantly more bitter than the barbiturate Nembutal (3-4 times more bitter by memory), and assumed the bitterness was perhaps reflecting the alleged toxicity of the drug.
The effect was your classic barbiturate sedative-hypnotic effect, just much stronger than your typical barbiturate drug. After taking 80mg one subject claims he felt like his weight had gone from 100kg to 300kg and was so sedated he could barely move. He slept for 14 hours straight, according to the write up. One user took 40mg and claimed that after an hour he felt it had the same effect as 260mg of phenobarbital. Another user who took 120mg reported vertigo, effects on his "working" memory, and nausea ending with profuse vomiting. One female took 40mg and was "smashed after an hour", while another user took 40mg in total (20mg and another 20mg an hour later) and he felt it was similar to him being affected by alcohol. So, going by those texts, I would assume that the toxicity would at least be partially validated and that one of these users could have indeed died from ingesting 600mg.
Pentyl groups, at least it seems, tend to produce the most toxic of barbiturates, and because this drug appears to be fluorinated, thereby inhibiting it's metabolic mechanisms, its toxicity could increase, but a MLD of just 600mg seems a tad low for a barbiturate. Virtually all barbiturates start at ~1.5g for a MLD, with one notable exception - pentobarbital which is said to be ~1g.
Strangely enough, I used Flynnal as my pseudonym on this forum.
Tell me your thoughts. It looks like a very strange drug, and in this day and age, I'm beginning to wonder if barbiturates are being taken off the back burner and coming back on to the market. Flynnal would be the ideal anxiolytic in the context of panic attacks, and would, at least going by it's toxicity, make a damn fine implementation for physician assisted suicide, and would replace Nembutal if it were not for it's disgustingly bitter taste according to the texts - I would say that simply reducing the amount of the drug taken as a drink (a la Dignitas) with added strong sweeteners would make it more palatable for that application. We all know barbiturates are bitter, but I can't even imagine what something 3-4 times as bitter as pentobarbital would taste like, pentobarbital sodium tastes absolutely revolting! (going from memory of trying pentobarbital years ago, I emptied the capsule and took the powder for a laugh - the worst thing I'd ever tasted!)
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