Gaz_hmmmm
Bluelighter
Does Fluorococaine convert into Cocaethylene or FluoroCocaethylene at all if you have alcohol whilst using it?
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N&PD Moderators: Skorpio
Fluorococaine & Cocaethylene
- Thread starter Gaz_hmmmm
- Start date
dread
Bluelighter
Fluorococaine yes, fluorotropacocaine no.
Twigs
Bluelighter
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http://www.ncbi.nlm.nih.gov/sites/e...D&[email protected]&Term=(("4'-fluorococaine"
So it should work like coke, but also effect serotonin uptake?
pofacedhoe
Bluelight Crew
indeed or maybe this might make it more euphoric although 100 x does sound sickening
Hammilton
Bluelighter
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- Sep 2, 2008
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- 3,435
No, it won't. 5HT reuptake inhibition offers fairly little in terms of mood brightening effects. 5HT release, on the other hand, is enjoyable, at least in conjunction with DA release.
I'm still too lazy to look up numbers, but if 5HT reuptake inhibition is that much stronger, I suspect it might be in the range of some marketed antidepressants.
5HT reuptake inhibition as is caused by common antidepressants like citalopram is very euphoric to me and to at least one other close friend of mine. 10mg citalopram without tolerance will make me extremly talkative, give me a lot of energy and make me feel general appreciation for like. It is also very empthogenic, similar to MDMA. That being said, the euphoria never reaches a level of Cocaine or MDMA, but I remember saying to myself "Wtf, this is what I always want to feel like" when I first tried them. Not everybody works the same way biochemically, nor do psychopharmacology books neccesarily give a good impression what substances feel like.
I'm still wondering about how strongly the 5HT reuptake would get inhibited and what transporters this molecule aims for. If it only inhibits SERT, some might get transported by the plasma membrane monoamine transporter which while not showing high Serotonine affinities, supposedly has a huge capacity compared to SERT. Now if the substance inhibits both there will surely be some extra serotonine floating around, but I couldn't say how strongly reuptake is inhibited by cocaine itself, "100x more potent" might still be really weak. Afaik cocaine does have some relevant effect on serotonin reuptake already though.
edit: whoops, thread was a bit old...I need to know a bit about this as well. i just finished with a small sample of 4-fluoro-cocaine.. the other night I did about 200 mg or so over a few hours.. then proceeded to do about a gram of 4-emc.. and after that finished up with about 3 beers.. not smart I know.. but everything was fine...
Today I finished the sample which was a bit less than what I used the other day maybe 100-150 mg? anyways... I drink 1 and a half beers and started feeling funny.. so I stopped drinking.. I think it was mostly in my head though.. after 7 hours I am going to have 1 beer and go to bed. I don't feel the effects of the 4-fluorococaine specifically anymore.. but I do still feel serotogernic vision brightness left over from using 4-mmc, 4mec, 4-emc, 4fa, and 4fc.. all in a 3 day binge..
sekio
Bluelight Crew
I see no reason transesterification would not happen.
I don't think that purported 4-FC on the market is f-fc, like vecktor said. Ecoginine (sp) (a key precursor) is controlled almost everywhere cocaine is.any idea on the supposed half life.. I've read through every scientific study I could find.. some about rhesus monkeys.. even some books on the synthesis of it but if they mentioned that detail it went over my head.. I have no way of knowing for sure if it was the Real 4-fc without a lab to test it.. but it came from the most respected and knowledgeable vendor I know and when I say knowledgeable I mean he has a degree in chemistry himself.. also he sourced it from another country.. it was even in a rocky form just like cocaine is and numbed my face.. the effects were similar to real coke but just much weaker and an extremely noticeable serotonin-like flood with it..
anyways.. I really wish I knew more info on this.. I went on a really stupid binge this week having taken 4-Fa yesterday and supposed 4-fc today.. after running through grams of 4-mec, 4-mmc, and 4-emc the previous three days. do you think this could result in a serotonin toxicity problem? and if the 4-fc does change to cocath.. how long would one have to wait before having a drink?.. good thing about the 4-fc is it had the weakest comedown of any of them.. with the exception maybe of the 4-fa.
ungelesene_bettlek
Bluelighter
why is this actually the case? why does serotonin reuptake inhibition only cause a subtle mood lift, while dopamine reuptake inhibition can cause strong stimulant effects? where does this difference come from?
That is a vast generalization. Serotonin reuptake nhibitors are still the most prescribed antidepressants we know and to many people they do offer "mood brightening effects", often after a single administration. Needless to say this isn't the kind of mood brightening that makes you want to IV the stuff, but I personally experience very profound effects on mood while under the influence of said substances that do go far past "not feeling depressed anymore" or being "flattened out":
@pofacedhoe
Our brain is extremely complex. There's many areas in the brain, each with multiple morphologically and functionally different types of neurons that have varying types and densities of receptors on their membranes. That being said, I really couldn't tell you much about how exactly a dat or sert inhibitor effects what we perceive as our mood, but these (serotonin/dopamine) systems dont stand independently from one another either. You'd have to get very deep into neurochemistry to really get a good understanding of what's happening up there. Hopefully I'll get there someday... Just don't believe anyone who wants to tell you that this or that specific neurotransmitter does this or that thing in your brain which will make you feel a certain way, they all cannot really function independently and oversimplification won't give you an understanding of what really happens in the brain.
