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Fencamfamine (or MDPV) + cocaine

haribo1

Ex-Bluelighter
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Nov 29, 2006
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Both of those uppers work by inhibiting dopamine reuptake as I understand it, so if you took some and then cocaine like 60 minutes later, would it not increase both the strength & duration of the cocaines effects (or, better from a legal POV, those p-F pseudotropine analogs?
 
Fencamfamine also causes dopamine efflux, although not on the same sort of scale as amphetamines.

Why would anyone want to sully a wonderful drug like fencamfamine with something like cocaine? (yes I'm on the verge of another fencamfamine rant! =D)
 
^Rant away young man, the stuff has a growing fascination for me as well. I'm thinking that ring substitution could be interesting. Didn't Shulgin make some that had massively long durations like 2-3 days. I'm also fascinated by the fact that it does interact with the opiate receptors since naloxone reversed some of the effects? Maybe making that nitrogen tertiary would make something MORE opiate-like?
 
Well, I've always been fascinated by lefetamine as well. Just how potent an opiate IS it? I would guess that with either compound a meta -OH on the phenyl ring would increase opiate potency. In the case of fencamfamine, swapping the NHCH2CH3 for N(CH3)2 would be nice. That bridge bends the molecule in a manner similar to tapentadol. Both would be legal (I assume) although I doubt that they are going to be particularly potent.
Have you tried lefetamine?
 
^Now, you HAVE let yourself down Mr F&B. I want, nay demand that you be a font of all knowledge on stimulants and psychedelics!
 
I always thought of fencamfamine as a dopamine reuptake inhibitor--like methylphenidate, prolintane or ethylcathinone, it is a bulky N-substituted amphetamine, right?

Anyway, to the original topic, combining dopamine reuptake inhibitors will just get you more uptake inhibition, with the added cardiac strain and arrhythmic potential of cocaine. Doesn't seem worth it and sounds possibly dangerous.

It's a damn shame they discontinued Reactivan and other fencamfamine products. While I've never tried said compound, it seems like a wonderful mild-ish, smooth-feeling general purpose psychostimulant--like a side effect free methylphenidate or a faster-acting, moire euphoric (and unfortunately, I suppose, reinforcing) modafinil. And with Reactivan, apparently they threw in some free B and C vitamins as well (which can't be a bad idea for stimulant users).
 
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^ Ever got a whiff of a bottle full of tablets that are a stimulant/vitamin mixture? Pretty rank - I used to get Apisate from a tame slimming clinic doctor when I was teaching (my excuse was that the school tuck shop was stored in my lab! Just too easy to drop a few coins in the draw & get a Mars bar), which was diethylpropion with added B vitamins - like a healthy Tenuate Dospan - but the smell was enough to put you off eating for a while, without the drug ever getting into your system.

Actually, prolintane (1-phenyl-2-(1-pyrrolidyl)pentane) isn't a bad stimulant at all. Not as good as fencamfamine, but still worth seeking out. Shame they added it to the MoDA at the same time they added fencamfamine.

If I could find some Reactivan anywhere, I'd be willing to put up with the twisted yeasty smell of the tablets. Of course what I'd really want though is 99 % + fencamfamine hydrochloride as I used to get from those friendly people at Aldrich (the first drug I ever administered IM was fencamfamine HCl and via that route, the euphoria associated with fencamfamine was every bit as good as the notorious stimulants of abuse like amphetamine derivatives and phenmetrazine, but without any peripheral effects - now that's why I go on about it so much); once they merged with the nazis at Sigma to become Sigma-Aldrich they wouldn't touch me with a 10 ft shitty pole. Truly a sad day all round...

I always thought of fencamfamine as a dopamine reuptake inhibitor--like methylphenidate, prolintane or ethylcathinone

It actually has about 20% of the dopamine releasing activity of dexamphetamine (if I remember correctly), which possibly did give it that little bit extra that the likes of methylphenidate etc lack
 
wow a living relic who remembers aldrich before they were sigma-aldrich...we should study you :)
 
Wouldn't prolintane be fairly longacting since it hasnt got any polarity or metabolic weaknesses.

A chemist of average intelligence can see how easily made this compound is. Although interesting, it doesn't really impress on me as being what I would call superior to pyrovalerone, just longer duration and perhaps lower dose.
 
You're talking about this compound...


fencamfamin%20(dl-n-ethyl-3-phenylbicyclo%5B2,2,1%5Dheptan-2-amine)43.png


(DL-N-Ethyl-3-phenylbicyclo[2,2,1]heptan-2-amine)....right?


What about the comming down of this stuff?

But your ^^*BIG GRINSing* tells my it was it worth anyhow... :)

I realy loved Methylphenidat because it boosts my brain much more than D-Amphetamine - excepted of the disgusting abturn of it. Some opioide "side"-effects are very welcome to me to...
 
^
If I could find some Reactivan anywhere, I'd be willing to put up with the twisted yeasty smell of the tablets. Of course what I'd really want though is 99 % + fencamfamine hydrochloride as I used to get from those friendly people at Aldrich (the first drug I ever administered IM was fencamfamine HCl and via that route, the euphoria associated with fencamfamine was every bit as good as the notorious stimulants of abuse like amphetamine derivatives and phenmetrazine, but without any peripheral effects - now that's why I go on about it so much); once they merged with the nazis at Sigma to become Sigma-Aldrich they wouldn't touch me with a 10 ft shitty pole. Truly a sad day all round...

FCF is sooo smooth. a complete gem IMHO.
thanks to the MoDA I will probaly never sample it again, but I do wonder about the 3,4-dichlorophenyl analogue and a few other more subtle variations that might keep the magic.
there is also the potential to use a monoterpene type structure in place of the norbornane.
 
FCF is sooo smooth. a complete gem IMHO.
thanks to the MoDA I will probaly never sample it again, but I do wonder about the 3,4-dichlorophenyl analogue and a few other more subtle variations that might keep the magic.
there is also the potential to use a monoterpene type structure in place of the norbornane.

Interesting, never tried any of these compounds. Lazy question but is femcamfamine sold on the market as a mixture of isomers?
 
Interesting, never tried any of these compounds. Lazy question but is femcamfamine sold on the market as a mixture of isomers?

I think reactivan was pure trans but the two possible optical isomers.

I don't think it is available any more, the last place I knew of was South Africa
 
It actually has about 20% of the dopamine releasing activity of dexamphetamine (if I remember correctly), which possibly did give it that little bit extra that the likes of methylphenidate etc lack

mmm...any other agents that achieve this (for many) 'happy medium' in mechanism of action?

the euphoria associated with fencamfamine was every bit as good as the notorious stimulants of abuse like amphetamine derivatives and phenmetrazine, but without any peripheral effects

mmm...In the absence of peripheral effects, does one still yield those nice bodily tingles? I'd imagine that in many users, euphoria links partially to perception and assessment of bodily effects (actual and centrally somato-sensory). . .

ebola
 
Yeah ebola, I actually quite like the peripheral effects of amphetamine. I often wonder how much of the high I get from 120mg pseudoephedrine is psychosomatic, because I associate the body rushes with happy memories of afternoons spent devouring whole textbooks on adderall.
 
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