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Feeling super sleepy on MDMA - Too much or too little?

You gave her 75mg? Or am I missing something?

I can't believe anyone is saying this is a "too much" reaction. 75mg is a pretty teensy dose. Stop skimping on your girlfriend.
 
Yeah i get sleepy as well, especially have a high dose initially. Hits you like a ton of bricks....like 500mg at once
 
I have exact same reaction! I can't usually fall asleep but feel so tired need to lay down. Most friends get really talkative/energy but I usually lay down, curl up and just close my eyes feeling very drained. Like feeling ok but drained. I don't do E anymore for like 5 years but it almost always made me tired, if it was pure mdma. (even had mdma powder before, same thing!!)

There's moments of happy thoughts but overall am tired, weak feeling and very cold! I feel like I want to be held too and just go under covers to rest. :?
 
yeah 75mg is low, i'd say go for 100-150mg dose next time when you giver her mandy, weigh it up on some scales so you know for sure.
 
This happens to me fairly constantly. Thats why I stopped dosing over 100 mg if i can help it (I have to eye my caps up). I get completely peaceful with the world but my legs feel like 10000 pounds and it would feel like a chore to move. I don't find this aspect of MDMA euphoric in the least, in fact it almost ruins raves for me when I over dose because I love to dance and if I can't dance I feel like I wasted my money. I have a very small window of perfection.
 
Too much is more likely to make you feel sleepy / floored / not wanting to stand up etc. Take a smaller dose and add some caffeine to the mix - it really works wonders.
 
Bearlove said:
Too much is more likely to make you feel sleepy / floored / not wanting to stand up etc. Take a smaller dose and add some caffeine to the mix - it really works wonders.
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Would previous dosing with a methamphetamine pill, say, 2-3 hours beforehand, work equally well? We use 5-htp and r-Alpha Lipoic Acid as supplements to our MDMA / MDA / MDEA / etc consumption.
 
My 2 speculative guesses:

1. Serotonin regulates (amongst other things) our sleep patterns and therefore it could make you feel tired, especially a large dose releasing all the serotonin.

2. Serotonin is linked with the neurochemical melatonin. Melatonin is responsible for making you feel tired and drowsey in order to sleep. While my knowledge is limited, the increased serotonin could raise the melatonin crossing the blood-brain barrier and make you feel tired.

Just some thoughts as to why we feel floored, stony and tired when MDMA is a stimulant. Its my personal opinion that large doses cause such a large influx of serotonin crossing the blood-brain barrier that melatonin is significantly raised making us feel euphoric, but chilled out and tired. The bit I don't get is that your s/o only took 75mg which is not a large dose in theory. I have a low tolerance to MDMA and have been slightly floored on 100MG. It's known that the dose-response ratio for MDMA is quite eratic. It doesn't simply show an even positive correlation between amount taken and intensity of experience. Erowid seems to suggest that the dose-response curve gets far steeper at 100MG+. Personally I think the threshold is more independent, in my case I would guess that the low-intensity threshold is breached at 90MG and after that the MDMA taken feels exponentially stronger. For your wife, the intensity threshold may be breached at an amount of MDMA recognised to be very low (60MG for example). Hypothetically speaking, the 15mg's of surplus MDMA could cause the over-stimulation of serotonin, increased melatonin and thus the feelings of tiredness.

On the other hand, the low dose taken might be causing an under-stimulation. Since it appears your setting is chilling at home on the sofa listening to music? A non-stimulating, relaxing setting where you would feel comfortable sober would impact the MDMA high and make it more chilled. Might be a dumb suggestion, but just try screaming as loud as you can. It worked for me once when I was floored and brought me back from the dreamy state I was previously in and then I felt far more energetic and euphoric.

The dose-response relationship really interests me and its inevitable that it's far more complex than any of the literature has covered. If only it wasn't illegal and researchers could actually research it more conclusively we could find out more about how it varies. There's no doubt in my mind that the dose can completely vary the neurochemicular balance in the brain and therefore completely change the experience.

I wouldn't question your product, i'd say it is infact more of an indicator of pure MDMA. Adulterants are typically reported to make it feel more speedy, trippy or weak for example. Rarely are adulterants reported of making MDMA feel more relaxing and induce tiredness, but it's not impossible I guess.

My recommendations would be to try experimenting with dose and set/setting. Go to a music event (or something more stimulating of your choice) you would enjoy sober and try giving her 75mg's and see it's still a lethargic experience. If it is, you could conclude that it's not the setting and it's the dose. Try more or less in a similar setting at a later date and just see how she reacts. Remember mindset can play a part in the experience, if she is expecting to be tired from the MDMA it could influence the tired feelings in a sort of placebo effect, try the screaming technique to see if it changes anything.

Hope some of this helped.
 
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I might be able to offer some info.

If she isn't on other medications and it's truly MDMA, then she could lack the ability to fully break it down. Whenever I take MDMA by itself I feel the high for about 30 minutes then it completely vanishes like someone turned a switch off, and all of the after effects begin. That includes fatigue.

I've had genetic testing done (for other reasons) and my CYP2D6 liver enzyme has a variant that does not allow me to fully process MDMA. Some people are just rapid metabolizers: they take it, and it runs its course quickly. But I have the actual side effects like the downer still, which means I am only a partial metabolizer.

You should ask your gf if anti-histamines or opiates like codeine work on her, because those are processed by CYP2D6 as well. When I take codeine my body doesn't convert it to opiate, I just get a bitter taste in the mouth and feel like shit.
 
even with a clean test, your test kit cant tell the difference between MDMA, MDEA, and MBDB. theres a small chance your pills might have some MDEA in them, it used to be very popular in the 90s. try mixing your rolls with a little bit of caffeine
 
Horrux said:
Would previous dosing with a methamphetamine pill, say, 2-3 hours beforehand, work equally well? We use 5-htp and r-Alpha Lipoic Acid as supplements to our MDMA / MDA / MDEA / etc consumption.
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I wouldn't (personally) use the term 'equally well' when talking about the effects of Meth vs caffeine :0 - Taking any stimulant before hand will usually stop you feeling that 'floored' feeling that MDMA can give. I would normally say caffeine does the job - if your stim of choice is meth then yes that will also prevent the floored feeling but obviously comes with its own risks / risks of combining drugs etc.

When I was raving I would very rarely take MDMA alone to club and often dosed with stims like amphetamine etc.
 
This is exactly why I don't really like pure mdma. It mostly just makes me feel tired and stupid. To me real ecstasy is a mix of mdma and/or mda and methamphetamine. mda and meth are both better for making me dance and talk all night, which is what i'm looking for in an e pill. mdma by its self is kinda boring, i'd take a couple of bumps of good meth over some mdma any day.
 
Thats happened with me before while doing around 100-200mg of pretty good powder. I've fallen asleep randomally, and blanked out until the next morning and my moms friend woke us up we both apparently sat there with our eyes rolling around in our heads, she thought we were high on H lol.
 
MDMA deffintly floors the hell out of me, I use meth or dexies to keep me awake it also makes for a different roll aswell, shitloads of energy still can get nice and munted rollign eyes etc but being floored is unheard of
 
Foreigner said:
I might be able to offer some info.

If she isn't on other medications and it's truly MDMA, then she could lack the ability to fully break it down. Whenever I take MDMA by itself I feel the high for about 30 minutes then it completely vanishes like someone turned a switch off, and all of the after effects begin. That includes fatigue.

I've had genetic testing done (for other reasons) and my CYP2D6 liver enzyme has a variant that does not allow me to fully process MDMA. Some people are just rapid metabolizers: they take it, and it runs its course quickly. But I have the actual side effects like the downer still, which means I am only a partial metabolizer.

You should ask your gf if anti-histamines or opiates like codeine work on her, because those are processed by CYP2D6 as well. When I take codeine my body doesn't convert it to opiate, I just get a bitter taste in the mouth and feel like shit.
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Thank you for the very enlightening reply.

Antihistamines and codeine both work splendidly on her, after repeated and thorough (and enjoyable, in the case of Codeine) testing.

I think we need to get her stimulated or get the dose right. I think next time we do Ecstasy (during the upcoming holidays), it will be after a good bout of speed.

I'm still a bit unsure how to time and dose the combo for her, but I think we'll try what makes the most sense and take it from there? I know not to take speed after E, given the higher toxicity of speed after the MDMA experience, even though we do use 5-htp and r-ALA, so we'll have to look into that I guess.
 
Some people just have this reaction to MDMA...the pure stuff anyway. My gf literally falls asleep after 30 minutes right in the middle of every roll (she does the same with good 4-FA). I don't fall asleep, but MDMA is definitely not the most "alert" drug I've encountered.

I've always heard amphetamines or caffeine are added to pills to offset the drowsiness some people get. You might try a very low dose of another stimulant w/ your MDMA next time.
 
Horrux said:
Thank you for the very enlightening reply.

Antihistamines and codeine both work splendidly on her, after repeated and thorough (and enjoyable, in the case of Codeine) testing.

I think we need to get her stimulated or get the dose right. I think next time we do Ecstasy (during the upcoming holidays), it will be after a good bout of speed.

I'm still a bit unsure how to time and dose the combo for her, but I think we'll try what makes the most sense and take it from there? I know not to take speed after E, given the higher toxicity of speed after the MDMA experience, even though we do use 5-htp and r-ALA, so we'll have to look into that I guess.
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If you do speed before MDMA then it will be harder to isolate MDMA's effect, but I can understand why getting high and just having something work is more important. I'm just suspicious of the liver enzymes because MDMA has the same effect on me as your gf - short term euphoria and then it ends - but MDA works perfectly on me. I find if I combine MDA with MDMA, I get the full MDMA effect. Somehow the MDA "carries" it.

I haven't tried MDMA + speed but maybe it would have a similar helpful effect to MDA + MDMA. Just keep in mind that if you do them together you should cut the doses of each in half because they potentiate each other.
 
^ actually, instead of cutting the dose of both in half I would take a slightly lesser dose of MDMA with around 15mg of speed. Nothing more, too much speed in a roll makes it really shitty and full of side effects.

Also, don't take the speed 2 hours before... you would want to take them at the same time. If you have speed pills, I'd take like 1/4 or even 1/8th of the pill. You don't need much at all, even 5mg of meth would be plenty to add some stimulation.
 
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