CocaColbenzo
Greenlighter
- Joined
- Aug 26, 2017
- Messages
- 21
Well I'm currently taking 1000mg of Clarithromycin. A strong inhibitor of CYP450-3A4 Enzyme. I've also been taking 1mg Lorazepam a day for over 2 years. I tapered it down to 0.5mg for a few weeks but after starting the Clarithromycin, i haven't had any Lorazepam in 48 hours and I'm starting to feel fucked. Slight feelings of sinking through chairs when sat down, minor vertigo sometimes but i just feel incredibly weird and disorientated. My orthopedic specialist said today to take absolutely no Lorazepam until i speak to my doctor, because of the strong drug interaction. But my doctor wont speak to me yet so i figured i don't have many options but to ask Bluelight! Also as a side question, I have a diet high in some psychoactive herbs such as nutmeg and parsley. I don't take them recreational, but my diet is rich in them. This has never caused any problem but could this cause issues with the Clarithromycin? Just going off the basis of most drugs are around 3 times stronger with this medication. So if i was to consume 2-3g of nutmeg in a daily diet, that would be like 9g no? Or does the CYP450-3A4 enzyme not have any effect in the psychoactive compounds in these herbs?