Opioids Extreme reaction to Espranor.

[Kurt Cobain]

I

Thank God I am not the only one that it is poison for.
These NHS Doctors know nothing Amigo they think we are all tonto & estúpido, well they are nothing put malditas putas to the Big Pharma people who sell this stuff to them.


I have had PAWS before, everything seems flat, you cannot get any joy from anything, life takes on a total Nihilist viewpoint & even suicide is too much, I am well versed in it sadly.
Yes all the junkies I hang out with have said I am "A lifer" & high chance I'll be a junkie for life but I accept it, heroin isn't even a "drug" anymore to me, it's a part of daily life such as eating food & drinking water is to everyone else, I need Heroin to just get out of bed. The odd thing is even on a high dose of heroin that would kill most people or even an "average" junkie I can go to work & function like a normal person, it's not till I have my unemployment payment from the state I go on a real binge for 3-5 days, I will nod/ gouge when I smoked several grams of Smack but upto that point I need it to function & people can't tell I am "high" as a general rule, I don't "nod out" in public etc like the unprofesional junkies do & those who CANNOT handle their heroin, I despise these types they have NO class about them.
Who the fuck gets loaded on Fent or some Nitazine & goes on the nod in public FFS? It's equal to being caught having sex in public in a toilet or behind a bush imho.

I had a look online a few days ago, back in 2012 the Police where I live pushed for legal Diamorphine scripts as where I live in very bad for heroin addiction, it didn't happen but I am going to press this issue now, what have I got to loose?

I know in places over by the Netherlands prescription heroin is fastly becoming the gold standard for maintence. The most destructive parts of addiction typically comes from not being able to get your drug, the money associated with getting said drug and then over here in the states you gotta worry about deadly nitazenes and fetty which is pretty much all we got now. You give the addict his drug of choice and watch how they can get their life somewhat back in order. I think it's a far better alternative to subs or methadone which is notorious for how hard it is to get off of it, at least with smach it's 4-7 days compared to subs and methadone which is months. Subs and methadone shouldn't be given to people who actually want to get clean at some point, it just makes it so much harder than the problem was to behind with. I don't think it's a grsat MAT drug either, so many people I know on subs or methadone still using their DOC ontop so what is it even doing for MAT purposes? It helps some no doubt but the number of people who regret it VS praise it is mostly one sided.

 

[Kurt Cobain]

they should be taken out & shot.

if you lost your script for any reason & had to do a sudden detox off that level with withdrawl would be brutal, YET AGAIN it shows to me doctors only know "book wisdom" which isn't equal to "lived experience"
I can read any text or book about how to drive a WRC car, it's a very different thing when I get into one on a gravel road, have 400 BHP at the pedal & I feed the clutch out for the first time.

Book wisdom is worth fuck all, it's equal to pissing into the Ocean.

These doctors are fully aware by now of subs downsides and it's low efficacy for actually getting people abstinent they just don't care. They're there to make money, big pharma found their new oxy and it's typically accepted so they're running with it and getting as many people hooked for as long as they can.

 

[Zopiclone bandit]

The most destructive parts of addiction typically comes from not being able to get your drug, the money associated with getting said drug and then over here in the states you gotta worry about deadly nitazenes and fetty which is pretty much all we got now. You give the addict his drug of choice and watch how they can get their life somewhat back in order.

Amen to that.
100% truth spoken there.

I have worked jobs such as Industrial removal, household removal, Manual Labour on farms etc with a smack habit, as long as I got some heroin I could do HARD manual labour with the best of them, if I had no smack I am in bed shaking, shitting, puking etc.......

 

[Zopiclone bandit]

These doctors are fully aware by now of subs downsides and it's low efficacy for actually getting people abstinent they just don't care. They're there to make money, big pharma found their new oxy and it's typically accepted so they're running with it and getting as many people hooked for as long as they can.

to take a quote from Kurt Cobain "You know your right" #smiles
Yes I am a HUGE Nirvana fan & sadly am old enough to remember them from the 1900's.

I have always wanted to ask an American this & I will take my chance now, you lot are upto the eyeballs in Mexican Fent & that stuff, I'm 99% sure you understand addiction here but have you ever tried anything apart from Mexican brown tar heroin or Fent?
The UK has had Afghan & what on the street is called "PK" gear (PK gear stands for "Paki" gear, it's to let the buyer it comes from the tribal hills of Pakistan since The Taliban took over, I use the term "Paki" in NO RACIST way, it's what the muslim / afghan / pakistan men who sell it call it from their own mouth. We have so much brown smoking heroin it's insane, every now & again Fent turns up but most of the UK supply comes in from the source places of Pakistan & Afghan Northern Alliance held areas.

My experience with Fent when it was given I.V., was "cold" a bit like morphine, it has NONE of the warm feeling that good Afghan heroin has, Fent to me is a no brainer, it's NOT Smack & anyone who's only ever used Fent has NO IDEA what good heroin feels like.

 

[4DQSAR]

I don't think that data is inherently bad. But from my very limited experience, it does seem as if my local HR agency has noted that buprenorphine isn't a good option - at least not the way it's beng prescribed.

I just checked and Reckitts supplied ARC in Lexington with buprenorphine as early as 1972 with the first protocol detailed in 1975. That protocol could not be more different than the way the drug is now being prescribed.

I just remembered that when Bentley undertook research on the class of compound that bears his name, research funding came from McFarlen-Smith and they wanted a cheaper alternative to codine! So even when the extreme potency of some examples was noted, that wasn't the aim of the work.

But it does seem odd that NOWHERE is there data on the safety profile of the huge doses of buprenorphine apparently being prescribed. It's a loophole as being an old drug, phase IV trials AKA pharmacovigilance does not apply. Any new medicine - the maker legally has to record severe outcomes.. But not with a 50+ year old medicine...

I knew someone prescribed buprenorphine and they were involved in a serious car accident... so no analgesia was avaiable. Seems that while not common, it's not even expleined to doctors that buprenorphine precludes the use of rescure analgeais as those opioids with the potency to overwhelm the MOR blockade are not found outside of hospitals.

 

[Zopiclone bandit]

I admit it's a guess but I always assumed the single large dose was chosen to allow for supervised consumption.

Hell no, well not on my blue script.
I was going up by 2mg till I got to 16mg & then I was meant to see a doctor to "have a talk about coming back down" well that "doctor" can go fuck herself, I highly question where her doctorate degree was given from, the local Aldi imho.

I try to be Stoic as possible in "junk sickness" BUT I wanna speak to anyone who has had a sudden loss of script when on 16mg of espranor & know what happened to them, I am betting they had days of a withdrawl from HELL.

Maybe the freeze drying of Bupe to make this poison known as "espranor" does something to the "structure" of the drug, my science wisdom is very bad, I got GCSE science & you are way above me in these things but I am sure the freeze drying of Bupe does something to it.

I can Promise you it's fucking poison!!!!!!!

 

[4DQSAR]

As I pointed out - EVERYONE is rapidly worked up to 16mg and then... at some point... they MAY consider reducing that dose.

But I can only assume the HR staff did not trust that concept as they were pretty open about using a pill cutter and suggesting client only take as much as needed.

I haven't named them so they can't get into trouble but it does seem they understood that buprenorphine was being abused by the makers, not the consumers.

 

[Zopiclone bandit]

But it does seem odd that NOWHERE is there data on the safety profile of the huge doses of buprenorphine apparently being prescribed. It's a loophole as being an old drug, phase IV trials AKA pharmacovigilance does not apply. Any new medicine - the maker legally has to record severe outcomes.. But not with a 50+ year old medicine...

So anyone who has a savage reaction to it has nowhere to report it? Make NO MISTAKE junkies I have known for 17 years looked at me when I was in w/d's with this stuff & said "Fuck me you look sick" he said I had turned 100% grey in the face, like all the blood had left me & I was actually grey, he told me a few days later he did think of dailing 999 as he had NEVER seen anyone that colour.

Someone needs to report this foul stuff, someone will die from this I promise you.

I knew someone prescribed buprenorphine and they were involved in a serious car accident... so no analgesia was avaiable. Seems that while not common, it's not even expleined to doctors that buprenorphine precludes the use of rescure analgeais as those opioids with the potency to overwhelm the MOR blockade are not found outside of hospitals.

put this in simple English please, I think I understand but i'm not 100% understanding it.

 

[Zopiclone bandit]

he said I had turned 100% grey in the face, like all the blood had left me & I was actually grey, he told me a few days later he did think of dailing 999 as he had NEVER seen anyone that colour.

A person who is "grey in the face" is likely experiencing a medical issue, as the symptom usually indicates a lack of blood flow or oxygenation, often caused by a sudden drop in blood pressure or shock [1]. This can be a sign of a medical emergency.
Potential causes include:

• Shock: A life-threatening condition where the body isn't getting enough blood flow [1].
• Fainting (Syncope): A temporary loss of consciousness, often due to a sudden drop in blood pressure [1].
• Heart Problems: Conditions like a heart attack or heart failure can impair circulation [1].
• Severe Pain or Emotional Distress: The body's response to intense pain or fear can cause a pale, grey appearance

 

[4DQSAR]

put this in simple English please, I think I understand but i'm not 100% understanding it.

Buprenorphine means an ambulance crew cannot give morphine in cases whet it would usually be indicated i.e. severe visceral pain.

In a hospital, ketamine or a high potency opioid can be prescribed by an appropriate clinician. That used to mean an anethnbetist although I expect a registrar could also write for them.

 

[Kurt Cobain]

to take a quote from Kurt Cobain "You know your right" #smiles
Yes I am a HUGE Nirvana fan & sadly am old enough to remember them from the 1900's.

I have always wanted to ask an American this & I will take my chance now, you lot are upto the eyeballs in Mexican Fent & that stuff, I'm 99% sure you understand addiction here but have you ever tried anything apart from Mexican brown tar heroin or Fent?
The UK has had Afghan & what on the street is called "PK" gear (PK gear stands for "Paki" gear, it's to let the buyer it comes from the tribal hills of Pakistan since The Taliban took over, I use the term "Paki" in NO RACIST way, it's what the muslim / afghan / pakistan men who sell it call it from their own mouth. We have so much brown smoking heroin it's insane, every now & again Fent turns up but most of the UK supply comes in from the source places of Pakistan & Afghan Northern Alliance held areas.

My experience with Fent when it was given I.V., was "cold" a bit like morphine, it has NONE of the warm feeling that good Afghan heroin has, Fent to me is a no brainer, it's NOT Smack & anyone who's only ever used Fent has NO IDEA what good heroin feels like.

I've never had tar, we get Afghan brown and China white. I can still get straight H but it's a lot harder to come by, not a fan of fent irs not euphoric to me. I like H bc it gives me energy fent just knocks me out. I'm not the nodder type, while I enjoy a good nod from time to time I prefer to be awake to enjoy my buzz and get shit done. I've done most drugs though aside from the few rare pharmaceuticals that are hard to come by like barbituates and ludes. I agree that the new wave of opiophiles have no clue what good opiates are and they never will, fent has ruined it for them all they want is that nod and their tolerance is too fucked for dope. My friend turned to fent, first fucking opiate she's ever done, tried to warn her but ya know. Anyways she was dope sick and I offered her some very good, very pure bags of brown and not even a bun did her in. We call a ten stamp package a bun over here if you didn't know so roughly a gram of dope although my dealer always hooks me up and my bags typically double the standard. I swear she could've done 50 bags and be unphased, mind you she's been doing opiates for less than six fucking months. She lost so much so fast sue to fetty it's insane, such a shitty drug to loose everything too.

 

[Kurt Cobain]

I've never had tar, we get Afghan brown and China white. I can still get straight H but it's a lot harder to come by, not a fan of fent irs not euphoric to me. I like H bc it gives me energy fent just knocks me out. I'm not the nodder type, while I enjoy a good nod from time to time I prefer to be awake to enjoy my buzz and get shit done. I've done most drugs though aside from the few rare pharmaceuticals that are hard to come by like barbituates and ludes. I agree that the new wave of opiophiles have no clue what good opiates are and they never will, fent has ruined it for them all they want is that nod and their tolerance is too fucked for dope. My friend turned to fent, first fucking opiate she's ever done, tried to warn her but ya know. Anyways she was dope sick and I offered her some very good, very pure bags of brown and not even a bun did her in. We call a ten stamp package a bun over here if you didn't know so roughly a gram of dope although my dealer always hooks me up and my bags typically double the standard. I swear she could've done 50 bags and be unphased, mind you she's been doing opiates for less than six fucking months. She lost so much so fast sue to fetty it's insane, such a shitty drug to loose everything too.

I have no clue how strong her fent was, she started with blues which I've done the same pills and they were meh but the blue powder she started getting was fucking STRONG. I felt cold, borderline disassociated and just ya it wasn't it for me. I don't see the appeal especially when you consider you're literally destroying yourself so fast and for what? Just to go to fucking sleep for a few hours?? Nah g I'll stick to My dope, kratom, 7oh and mgm15. The shit we got now could be anything though I'm in PA like 5 hours from new Ken, the necrosis center of the world so it really is fucking anything.

 

[Zopiclone bandit]

I like H bc it gives me energy fent just knocks me out. I'm not the nodder type, while I enjoy a good nod from time to time I prefer to be awake to enjoy my buzz and get shit done.

Usually I am suspect about others online who say they know Heroin, you don't fit that camp at all, I can relate 100% to this.

. I agree that the new wave of opiophiles have no clue what good opiates are and they never will, fent has ruined it for them all they want is that nod and their tolerance is too fucked for dope

When I had NHS Fent (NHS is our medical system) it felt cold & a bit Ketamine-esque or like the comedown off 4-MeO-PCP, I wasn't that impressed with it & it was 250mcg I.V. so I had a "nice dose" of it #smiles

Anyways she was dope sick and I offered her some very good, very pure bags of brown and not even a bun did her in. We call a ten stamp package a bun over here if you didn't know so roughly a gram of dope

that is insane, if I was sick a gram would fix me very well & also hold me well into the next day, to still be truly sick from a gram of #3 or #4 Heroin is insane.
Yet again I have more evidence Fent & it's type aren't Heroin or Opiate based as I know them to be & I have NO desire to get a habit on that stuff.

 

[Zopiclone bandit]

she started with blues which I've done the same pills and they were meh but the blue powder she started getting was fucking STRONG.

blues? I have no grasp of what this is.
We sure don't have this in the UK, what is it?

PA is Pennsylvania right?
East coast, where the people from Holland first set up in the USA?

 

[Zopiclone bandit]

I'm in PA like 5 hours from new Ken, the necrosis center of the world

Welcome to The West Midlands, UK.
We are costing the UK $1,853,740.00 alone in my area, how bad is PA where you are?

 

[Kurt Cobain]

Usually I am suspect about others online who say they know Heroin, you don't fit that camp at all, I can relate 100% to this.



When I had NHS Fent (NHS is our medical system) it felt cold & a bit Ketamine-esque or like the comedown off 4-MeO-PCP, I wasn't that impressed with it & it was 250mcg I.V. so I had a "nice dose" of it #smiles



that is insane, if I was sick a gram would fix me very well & also hold me well into the next day, to still be truly sick from a gram of #3 or #4 Heroin is insane.
Yet again I have more evidence Fent & it's type aren't Heroin or Opiate based as I know them to be & I have NO desire to get a habit on that stuff.

Ya lying about how bad your addiction was is stupid and something kids do to fit in with the old heads in the crowd. It's nothing to be proud of but it has taught me a lot andiI greatly appreciate the lessons it has taught me.

I agree on the fent tho, I've had pharma fent in patches and the street shit, street shit feels dirtier but pretty much the same so long as it's straight fent and I whole heartedly agree it's not euphoric and has very dissassociatige qualities which is why I don't like it, strong as fuck but I wouldn't call it a good time and waste my money on it. It's dirt fucking cheap though, gram of powder here 5-10 bucks with my people at least.

I was suprised too but she could go through 40 pills a day and I'm willing to bet over a gram of the powder. It was actually scary how fast she went up and then down, genuinely fucking terrified me how fast it was destroying people

 

[Kurt Cobain]

blues? I have no grasp of what this is.
We sure don't have this in the UK, what is it?

PA is Pennsylvania right?
East coast, where the people from Holland first set up in the USA?

Ya Pennsylvania and blues are how fent first started, Mexicans were pressing fake roxys, the blue 30s and nobody knew for awhile but those are slowly being phased out around me and people pretty much only get powder now and it's typically blue or purple sometimes white with a blue hue

 

[Kurt Cobain]

Welcome to The West Midlands, UK.
We are costing the UK $1,853,740.00 alone in my area, how bad is PA where you are?

PA is ground zero for the fent issues not where it started that's be in the west but I think we could all agree here that PA is fucked when it comes to fent. Watch a docu on NEW KENSINGTON PA it's right by Philly. You'll find thousands upon thousands of needles, people all down the sidewalks for miles doing the fent fold, necrotic limbs are so fucking common now bc of the xylazine In the dope it's genuinely fucking scary. You'll find tons of info about it it's definetly the worst offender for anything fent related or at least top 3.

 

[thurston]

Yes and @4DQSAR I'm in the camp of believers that if 4mg Buprenorphine isn't ultimately enough, other options should be considered instead of raising the dose. That's just how our society has prescribed it. It is most "effective" for our purposes when taken in doses lower than 2mg Buprenorphine.

Back when I was taking bupe daily I kept it at 1.5-2 mg/day.

 

[Dilbert 47]

Began on Tuesday with my first dose of Espranor, I was meant to be going upto 16mg by a few mg's per day & I google searched this last night & it said 16mg is the MAX dose & I am 100% glad I never got there.

Anyway Tuesday evening I waited till I began to feel cold, sneeze, feel my body hurt etc (the basic start of a Heroin withdrawl) & I took 4mg which kicked in really quick after putting it on the top of my tongue, it helped & I slept for a good 8-10 hours that night.

Woke up the next day (Wednesday 26th November AKA yesterday) & still felt ok, I decided to wait till I began to feel sick to take more & the chemist didn't close till 6pm so I sat back & waited. Around 12.30pm - 1.15pm I began to feel VERY COLD & began to get very pissed off, that typical Heroin withdrawl sulky face, shitty mood where you wanna burn the world down etc & I still didn't go to the chemist but was shocked how bad I felt so fast. Give it another 45 mins I am in pieces, I have used heroin for 24 years & am UK based so we still have Heroin, our supply isn't Fent or any of the stuff in the USA & the way this rattle was coming on I have NEVER FELT BEFORE.

I had none of the gut issues you get in withdrawl BUT the dry heaving, gagging, dry throat issue, spraying stomach acid out of my nose was insane & heroin addicts will know how sharp your smell becomes in withdrawl well this damn poison made it 1000 times more worse than the most savage heroin withdrawl I ever known.

I will NEVER as long as I live touch Espranor, imho this stuff is NOT fit for Humans to take, how the hell it got a licence as a medicine & is sold by doctors as being "better" than methadone & a "painless withdrawl" is for the birds, it is lies!!!!!!

Anyone else had really bad effects off this damn stuff?

Also the Doctor wanted me to work upto 16mg, I am 100% sure a sudden withdrawl from 16mg of this stuff could make someone NOT be able to stand it & end their life!!!!!

I don't understand why you didn't just take another does at 4mg instead of waiting to get so ill .
I've been on espranor for nearly 10 years and I've never had any issues like that.
I'm on 16mg now but even 2mg will hold me for a day if I've abused my weekly prescription.
The biggest problem I have is I'm addicted to taking them now for so little affect .
Hope it worked out in the end.